Loss of SARM1 ameliorates secondary thalamic neurodegeneration after cerebral infarction

Targeting NLRP3 inflammasome modulates gut microbiota, attenuates corticospinal tract injury and ameliorates neurobehavioral deficits after intracerebral hemorrhage in mice

(2022) Linglong Xiao et al.   BIOMEDICINE & PHARMACOTHERAPY

Targeting autophagy using small-molecule compounds to improve potential therapy of Parkinson’s disease

(2021) Kai Zhang et al.   Acta Pharmaceutica Sinica B

Pharmacological SARM1 inhibition protects axon structure and function in paclitaxel-induced peripheral neuropathy

(2021) Todd Bosanac et al.   BRAIN

Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration

(2021) Henry Querfurth et al.   Molecular Neurodegeneration

Calcium Signaling Regulates Autophagy and Apoptosis

(2021) Pramod Sukumaran et al.   Cells

Programmed axon degeneration: from mouse to mechanism to medicine

(2020) Michael P. Coleman et al.   NATURE REVIEWS NEUROSCIENCE

Phosphorylation at S548 as a Functional Switch of Sterile Alpha and TIR Motif-Containing 1 in Cerebral Ischemia/Reperfusion Injury in Rats

(2020) Tao Xue et al.   MOLECULAR NEUROBIOLOGY

The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative Sarm1

(2020) Yuefeng Jiang et al.   NATURE

Pro-cathepsin D, Prosaposin, and Progranulin: Lysosomal Networks in Parkinsonism

(2020) Nahid Tayebi et al.   TRENDS IN MOLECULAR MEDICINE

Hypothalamic BMP9 suppresses glucose production by central PI3K/Akt /mTOR pathway

(2020) Yirui He et al.   JOURNAL OF ENDOCRINOLOGY

Injury-Induced Inhibition of Bystander Neurons Requires dSarm and Signaling from Glia

(2020) Jiun-Min Hsu et al.   NEURON

Do Clinicians Overestimate the Severity of Intracerebral Hemorrhage?

(2019) Elliot J. Tilling et al.   STROKE

Mechanisms of injury-induced axon degeneration

(2019) Chen Ding et al.   CURRENT OPINION IN NEUROBIOLOGY

Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss

(2019) Matthew A. White et al.   Acta Neuropathologica Communications

p62/ SQSTM 1: ‘Jack of all trades’ in health and cancer

(2018) Pablo Sánchez‐Martín et al.   FEBS Journal

2-Cl-MGV-1 Ameliorates Apoptosis in the Thalamus and Hippocampus and Cognitive Deficits After Cortical Infarct in Rats

(2017) Yicong Chen et al.   STROKE

MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2

(2017) Lauren J Walker et al.   eLife

Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lackingSarm1

(2016) Nils Henninger et al.   BRAIN

Unfolded protein response is activated in the ipsilateral thalamus following focal cerebral infarction in hypertensive rats

(2016) Jian Zhang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Chronic stress exposure following photothrombotic stroke is associated with increased levels of Amyloid beta accumulation and altered oligomerisation at sites of thalamic secondary neurodegeneration in mice

(2016) Lin Kooi Ong et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

(2016) Ángel Chamorro et al.   LANCET NEUROLOGY

Dynamic secondary degeneration in the spinal cord and ventral root after a focal cerebral infarction among hypertensive rats

(2016) Ge Dang et al.   Scientific Reports

SARM1 activation triggers axon degeneration locally via NAD+ destruction

(2015) J. Gerdts et al.   SCIENCE

Absence of SARM1 Rescues Development and Survival of NMNAT2-Deficient Axons

(2015) Jonathan Gilley et al.   Cell Reports

NOX4 regulates autophagy during energy deprivation

(2014) Sebastiano Sciarretta et al.   Autophagy

A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration

(2014) M Di Stefano et al.   CELL DEATH AND DIFFERENTIATION

Autophagy and cathepsin L are involved in the antinociceptive effect of DMBC in a mouse acetic acid-writhing model

(2013) Wei-wei Gu et al.   ACTA PHARMACOLOGICA SINICA

Characterization of long-term functional outcome in a murine model of mild brain ischemia

(2013) Mustafa Balkaya et al.   JOURNAL OF NEUROSCIENCE METHODS

Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction

(2012) Shihui Xing et al.   Autophagy

NAD+ administration decreases ischemic brain damage partially by blocking autophagy in a mouse model of brain ischemia

(2012) Chaobo Zheng et al.   NEUROSCIENCE LETTERS

dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway

(2012) J. M. Osterloh et al.   SCIENCE

Secondary Neurodegeneration in Remote Regions After Focal Cerebral Infarction

(2012) Jian Zhang et al.   STROKE

Autophagosomes accumulation is associated with β-amyloid deposits and secondary damage in the thalamus after focal cortical infarction in hypertensive rats

(2011) Jian Zhang et al.   JOURNAL OF NEUROCHEMISTRY