Targeting NLRP3 inflammasome modulates gut microbiota, attenuates corticospinal tract injury and ameliorates neurobehavioral deficits after intracerebral hemorrhage in mice

Gut Microbiota Dysbiosis Induced by Intracerebral Hemorrhage Aggravates Neuroinflammation in Mice

(2021) Xiaobo Yu et al.   Frontiers in Microbiology

Inhibition of P2X4R attenuates white matter injury in mice after intracerebral hemorrhage by regulating microglial phenotypes

(2021) Xiongjie Fu et al.   Journal of Neuroinflammation

Restoring Cellular Energetics Promotes Axonal Regeneration and Functional Recovery after Spinal Cord Injury

(2020) Qi Han et al.   Cell Metabolism

Alzheimer’s disease and gastrointestinal microbiota; impact of Helicobacter pylori infection involvement

(2020) Michael Doulberis et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Microbiota-gut-brain axis in health and disease: Is NLRP3 inflammasome at the crossroads of microbiota-gut-brain communications?

(2020) Carolina Pellegrini et al.   PROGRESS IN NEUROBIOLOGY

A practical guide to amplicon and metagenomic analysis of microbiome data

(2020) Yong-Xin Liu et al.   Protein & Cell

MitoQ attenuates brain damage by polarizing microglia towards the M2 phenotype through inhibition of the NLRP3 inflammasome after ICH

(2020) Weixiang Chen et al.   PHARMACOLOGICAL RESEARCH

New mechanism of neuroinflammation in Alzheimer's disease: The activation of NLRP3 inflammasome mediated by gut microbiota

(2020) Heping Shen et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Protracted Morphological Changes in the Corticospinal Tract Within the Cervical Spinal Cord After Intracerebral Hemorrhage in the Right Striatum of Mice

(2020) Anson Cho Kiu Ng et al.   Frontiers in Neuroscience

Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis

(2019) Eric M. Brown et al.   Cell Host & Microbe

Potential roles of gut microbiome and metabolites in modulating ALS in mice

(2019) Eran Blacher et al.   NATURE

Gut microbiota from NLRP3-deficient mice ameliorates depressive-like behaviors by regulating astrocyte dysfunction via circHIPK2

(2019) Yuan Zhang et al.   Microbiome

White matter repair and treatment strategy after intracerebral hemorrhage

(2019) Yi‐Bin Jiang et al.   CNS Neuroscience & Therapeutics

The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins

(2019) Vandana Deora et al.   GLIA

Inflammasome signalling in brain function and neurodegenerative disease

(2018) Michael T. Heneka et al.   NATURE REVIEWS NEUROSCIENCE

Targeting NLRP3 Inflammasome in the Treatment of CNS Diseases

(2018) Bo-Zong Shao et al.   Frontiers in Molecular Neuroscience

NLRP3 inflammasome in the pathophysiology of hemorrhagic stroke: A Review

(2018) Yujie Luo et al.   Current Neuropharmacology

Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway

(2017) Jun Zeng et al.   Journal of Neuroinflammation

Cordycepin confers neuroprotection in mice models of intracerebral hemorrhage via suppressing NLRP3 inflammasome activation

(2017) Yijun Cheng et al.   METABOLIC BRAIN DISEASE

Erythropoietin attenuates axonal injury after middle cerebral artery occlusion in mice

(2017) Rongliang Wang et al.   NEUROLOGICAL RESEARCH

Selective NLRP3 (Pyrin Domain–Containing Protein 3) Inflammasome Inhibitor Reduces Brain Injury After Intracerebral Hemorrhage

(2017) Honglei Ren et al.   STROKE

Gut microbiota dysbiosis contributes to the development of hypertension

(2017) Jing Li et al.   Microbiome

Psychobiotics and the Manipulation of Bacteria–Gut–Brain Signals

(2016) Amar Sarkar et al.   TRENDS IN NEUROSCIENCES

VSEARCH: a versatile open source tool for metagenomics

(2016) Torbjørn Rognes et al.   PeerJ

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

Peroxynitrite decomposition catalyst prevents matrix metalloproteinase-9 activation and neurovascular injury after hemoglobin injection into the caudate nucleus of rats

(2015) R. Ding et al.   NEUROSCIENCE

Receptor for Advanced Glycation End-Product Antagonist Reduces Blood-Brain Barrier Damage After Intracerebral Hemorrhage

(2015) F. Yang et al.   STROKE

Blood–brain barrier disruption induced by hemoglobin in vivo: Involvement of up-regulation of nitric oxide synthase and peroxynitrite formation

(2014) Rui Ding et al.   BRAIN RESEARCH

Quantitative gait analysis of long-term locomotion deficits in classical unilateral striatal intracerebral hemorrhage rat model

(2013) Yao Liu et al.   BEHAVIOURAL BRAIN RESEARCH

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

Ribosomal Database Project: data and tools for high throughput rRNA analysis

(2013) James R. Cole et al.   NUCLEIC ACIDS RESEARCH

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS