Early steps in the biogenesis of mitochondrially encoded oxidative phosphorylation subunits

Human mitochondria require mtRF1 for translation termination at non-canonical stop codons

(2023) Annika Krüger et al.   Nature Communications

Types and Functions of Mitoribosome-Specific Ribosomal Proteins across Eukaryotes

(2022) Vassilis Scaltsoyiannes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The ER membrane complex (EMC) can functionally replace the Oxa1 insertase in mitochondria

(2022) Büsra Güngör et al.   PLOS BIOLOGY

Cryo-EM insights into tail-anchored membrane protein biogenesis in eukaryotes

(2022) Irmgard Sinning et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

MTCH2 is a mitochondrial outer membrane protein insertase

(2022) Alina Guna et al.   SCIENCE

The function of prohibitins in mitochondria and the clinical potentials

(2022) Linda Oyang et al.   Cancer Cell International

AAA+ proteases: the first line of defense against mitochondrial damage

(2022) Gautam Pareek   PeerJ

Mechanisms and regulation of protein synthesis in mitochondria

(2021) Eva Kummer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural and molecular mechanisms for membrane protein biogenesis by the Oxa1 superfamily

(2021) Melanie A. McDowell et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanism of membrane-tethered mitochondrial protein synthesis

(2021) Yuzuru Itoh et al.   SCIENCE

A stalled-ribosome rescue factor Pth3 is required for mitochondrial translation against antibiotics in Saccharomyces cerevisiae

(2021) Soichiro Hoshino et al.   Communications Biology

Structural basis of translation termination, rescue, and recycling in mammalian mitochondria

(2021) Eva Kummer et al.   MOLECULAR CELL

Mitochondrial Protein Translation: Emerging Roles and Clinical Significance in Disease

(2021) Fei Wang et al.   Frontiers in Cell and Developmental Biology

Functional Diversity of Mitochondrial Peptidyl-tRNA Hydrolase ICT1 in Human Cells

(2021) I.V. Chicherin et al.   Frontiers in Molecular Biosciences

Maintaining mitochondrial ribosome function: The role of ribosome rescue and recycling factors

(2021) Franziska Nadler et al.   RNA Biology

Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors

(2021) Sven Dennerlein et al.   eLife

Role of Prohibitins in Aging and Therapeutic Potential Against Age-Related Diseases

(2021) Misa Belser et al.   Frontiers in Genetics

Mitochondrial Proteases: Multifaceted Regulators of Mitochondrial Plasticity

(2020) Soni Deshwal et al.   Annual Review of Biochemistry

Structural basis for membrane insertion by the human ER membrane protein complex

(2020) Tino Pleiner et al.   SCIENCE

Molecular Connectivity of Mitochondrial Gene Expression and OXPHOS Biogenesis

(2020) Abeer Prakash Singh et al.   MOLECULAR CELL

An ER translocon for multi-pass membrane protein biogenesis

(2020) Philip T McGilvray et al.   eLife

Elongational stalling activates mitoribosome-associated quality control

(2020) Nirupa Desai et al.   SCIENCE

Prohibitins: A Critical Role in Mitochondrial Functions and Implication in Diseases

(2019) Anna Signorile et al.   Cells

Membrane Protein Integration and Topogenesis at the ER

(2019) Martin Spiess et al.   PROTEIN JOURNAL

Guiding tail-anchored membrane proteins to the endoplasmic reticulum in a chaperone cascade

(2019) Shu-ou Shan   JOURNAL OF BIOLOGICAL CHEMISTRY

MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition

(2019) Jakob D. Busch et al.   Cell Reports

Molecular Wiring of a Mitochondrial Translational Feedback Loop

(2019) Roger Salvatori et al.   MOLECULAR CELL

High-resolution structures of mitochondrial ribosomes and their functional implications

(2018) Philipp Bieri et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Assembly of mammalian oxidative phosphorylation complexes I–V and supercomplexes

(2018) Alba Signes et al.   Essays in Biochemistry

Biogenesis of the bc 1 Complex of the Mitochondrial Respiratory Chain

(2018) Mama Ndi et al.   JOURNAL OF MOLECULAR BIOLOGY

High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane

(2018) Anurag P. Srivastava et al.   SCIENCE

Mitochondrial cytochrome c oxidase biogenesis: Recent developments

(2018) Alba Timón-Gómez et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins

(2018) Matthew J Shurtleff et al.   eLife

The Multiple Levels of Mitonuclear Coregulation

(2018) R. Stefan Isaac et al.   Annual Review of Genetics

The ribosome receptors Mrx15 and Mba1 jointly organize cotranslational insertion and protein biogenesis in mitochondria

(2018) Braulio Vargas Möller-Hergt et al.   MOLECULAR BIOLOGY OF THE CELL

EMC Is Required to Initiate Accurate Membrane Protein Topogenesis

(2018) Patrick J. Chitwood et al.   CELL

Regulation of Mitochondrial Electron Transport Chain Assembly

(2018) Sara Cogliati et al.   JOURNAL OF MOLECULAR BIOLOGY

Cryo-EM structure of the yeast respiratory supercomplex

(2018) Sorbhi Rathore et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular insights into them-AAA protease–mediated dislocation of transmembrane helices in the mitochondrial inner membrane

(2017) Seoeun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of the human mitochondrial ribosome in native states of assembly

(2017) Alan Brown et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The structure of the yeast mitochondrial ribosome

(2017) Nirupa Desai et al.   SCIENCE

Structures of the human mitochondrial ribosome in native states of assembly

(2017) Alan Brown et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

(2017) Marcel Morgenstern et al.   Cell Reports

Identification of Oxa1 Homologs Operating in the Eukaryotic Endoplasmic Reticulum

(2017) S. Andrei Anghel et al.   Cell Reports

Structure and Function of the Mitochondrial Ribosome

(2016) Basil J. Greber et al.   Annual Review of Biochemistry

Maintenance and Expression of Mammalian Mitochondrial DNA

(2016) Claes M. Gustafsson et al.   Annual Review of Biochemistry

Organization and Regulation of Mitochondrial Protein Synthesis

(2016) Martin Ott et al.   Annual Review of Biochemistry

Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein

(2016) Ricarda Richter-Dennerlein et al.   CELL

Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria

(2016) Heather A. Feaga et al.   PLoS Genetics

Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation

(2016) Ryuta Ishimura et al.   eLife

YidC/Alb3/Oxa1 Family of Insertases

(2015) Seth W. Hennon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness

(2015) Uwe Richter et al.   JOURNAL OF CELL BIOLOGY

Integrating mitochondrial translation into the cellular context

(2015) Ricarda Richter-Dennerlein et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The complete structure of the 55S mammalian mitochondrial ribosome

(2015) B. J. Greber et al.   SCIENCE

Organization of the mitochondrial translation machinery studied in situ by cryoelectron tomography

(2015) Stefan Pfeffer et al.   Nature Communications

Organization of Mitochondrial Gene Expression in Two Distinct Ribosome-Containing Assemblies

(2015) Kirsten Kehrein et al.   Cell Reports

Making Proteins in the Powerhouse

(2014) B. Martin Hällberg et al.   Cell Metabolism

Delineation of C12orf65-related phenotypes: a genotype–phenotype relationship

(2014) Ronen Spiegel et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Assembly factors monitor sequential hemylation of cytochromebto regulate mitochondrial translation

(2014) Markus Hildenbeutel et al.   JOURNAL OF CELL BIOLOGY

Structural basis of Sec-independent membrane protein insertion by YidC

(2014) Kaoru Kumazaki et al.   NATURE

The Pet309 pentatricopeptide repeat motifs mediate efficient binding to the mitochondrialCOX1transcript in yeast

(2014) Angélica Zamudio-Ochoa et al.   RNA Biology

Structure of the Yeast Mitochondrial Large Ribosomal Subunit

(2014) A. Amunts et al.   SCIENCE

Structure of the large ribosomal subunit from human mitochondria

(2014) A. Brown et al.   SCIENCE

Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria

(2014) Shiori Akabane et al.   PLoS Genetics

A structural model of the active ribosome-bound membrane protein insertase YidC

(2014) Stephan Wickles et al.   eLife

Optic Atrophy and a Leigh-Like Syndrome Due to Mutations in the C12orf65 Gene

(2013) Gena Heidary et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

The Heme a Synthase Cox15 Associates with Cytochrome c Oxidase Assembly Intermediates during Cox1 Maturation

(2013) B. Bareth et al.   MOLECULAR AND CELLULAR BIOLOGY

The post-transcriptional life of mammalian mitochondrial RNA

(2012) Joanna Rorbach et al.   BIOCHEMICAL JOURNAL

Heme A biosynthesis

(2012) Lars Hederstedt   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A Heme-Sensing Mechanism in the Translational Regulation of Mitochondrial Cytochrome c Oxidase Biogenesis

(2012) Iliana C. Soto et al.   Cell Metabolism

Mitochondrial Protein Synthesis, Import, and Assembly

(2012) Thomas D. Fox   GENETICS

Mitochondrial AAA proteases — Towards a molecular understanding of membrane-bound proteolytic machines

(2011) Florian Gerdes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

TIM23-mediated insertion of transmembrane α-helices into the mitochondrial inner membrane

(2011) Salomé Calado Botelho et al.   EMBO JOURNAL

Cbp3–Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochromebsynthesis and assembly

(2011) Steffi Gruschke et al.   JOURNAL OF CELL BIOLOGY

Mutations in C12orf65 in Patients with Encephalomyopathy and a Mitochondrial Translation Defect

(2010) Hana Antonicka et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

(2010) Ricarda Richter et al.   EMBO JOURNAL

Identification of Novel Oxidized Protein Substrates and Physiological Partners of the Mitochondrial ATP-dependent Lon-like Protease Pim1

(2010) Aurélien Bayot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coa3 and Cox14 are essential for negative feedback regulation ofCOX1translation in mitochondria

(2010) David U. Mick et al.   JOURNAL OF CELL BIOLOGY

Surf1, Associated with Leigh Syndrome in Humans, Is a Heme-binding Protein in Bacterial Oxidase Biogenesis

(2009) Freya A. Bundschuh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Formation of the Redox Cofactor Centers during Cox1 Maturation in Yeast Cytochrome Oxidase

(2009) O. Khalimonchuk et al.   MOLECULAR AND CELLULAR BIOLOGY

Mss51 and Ssc1 Facilitate Translational Regulation of Cytochrome c Oxidase Biogenesis

(2009) F. Fontanesi et al.   MOLECULAR AND CELLULAR BIOLOGY

Prohibitin and mitochondrial biology

(2009) Marta Artal-Sanz et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

HMRF1L is a human mitochondrial translation release factor involved in the decoding of the termination codons UAA and UAG

(2008) Yusuke Nozaki et al.   GENES TO CELLS

A structure for the yeast prohibitin complex: Structure prediction and evidence from chemical crosslinking and mass spectrometry

(2002) Jaap W. Back et al.   PROTEIN SCIENCE