Two into one does go: Formulation development of a multipurpose combination vaginal ring releasing dapivirine and metronidazole for prevention of HIV infection and treatment of bacterial vaginosis
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Title
Two into one does go: Formulation development of a multipurpose combination vaginal ring releasing dapivirine and metronidazole for prevention of HIV infection and treatment of bacterial vaginosis
Authors
Keywords
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Journal
International Journal of Pharmaceutics
Volume -, Issue -, Pages 123572
Publisher
Elsevier BV
Online
2023-11-04
DOI
10.1016/j.ijpharm.2023.123572
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Note: Only part of the references are listed.- Expanding the pipeline for multipurpose prevention technologies: compounds with potential activity to prevent or treat HIV and other STIs
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- (2021) Michele N Austin et al. JOURNAL OF INFECTIOUS DISEASES
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- The ins and outs of drug-releasing vaginal rings: a literature review of expulsions and removals
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- (2019) Kathryn Peebles et al. SEXUALLY TRANSMITTED DISEASES
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- (2019) John W. McBride et al. JOURNAL OF CONTROLLED RELEASE
- The development of a silicone vaginal ring with a prostaglandin analogue for potential use in the treatment of canine reproductive disorders
- (2019) Veronika Nováková Tkadlečková et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Post-use ring weight and residual drug content as potential objective measures of user adherence to a contraceptive progesterone vaginal ring
- (2019) Diarmaid J. Murphy et al. CONTRACEPTION
- Drug stability and product performance characteristics of a dapivirine-releasing vaginal ring under simulated real-world conditions
- (2019) Diarmaid J. Murphy et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Towards a dapivirine and levonorgestrel multipurpose vaginal ring: Investigations into the reaction between levonorgestrel and addition-cure silicone elastomers
- (2019) Yahya H. Dallal Bashi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
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- (2018) McKenna C. Eastment et al. AIDS
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- (2018) Clare F. McCoy et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The Tablets, Ring, Injections as Options (TRIO) study: what young African women chose and used for future HIV and pregnancy prevention
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- (2018) CLINICAL INFECTIOUS DISEASES
- Lactobacillus -Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women
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- Experts explore the state of bacterial vaginosis and the unmet needs facing women and providers
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- Enhancement of dissolution rate through eutectic mixture and solid solution of posaconazole and benznidazole
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- Packing Polymorphism of Dapivirine and Its Impact on the Performance of a Dapivirine-Releasing Silicone Elastomer Vaginal Ring
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- Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition
- (2017) A C Hearps et al. Mucosal Immunology
- Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women
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- (2016) R. Karl Malcolm et al. ADVANCED DRUG DELIVERY REVIEWS
- Bacterial vaginosis: a critical analysis of current knowledge
- (2016) D Nasioudis et al. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
- Microbiome alterations in HIV infection a review
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- (2016) Jared M. Baeten et al. OBSTETRICAL & GYNECOLOGICAL SURVEY
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- (2015) Lindi Masson et al. CLINICAL INFECTIOUS DISEASES
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- A safety and pharmacokinetic trial assessing delivery of dapivirine from a vaginal ring in healthy women
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- Beyond HIV microbicides: multipurpose prevention technology products
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- (2009) J. Romano et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Safety and Pharmacokinetics of Dapivirine Delivery From Matrix and Reservoir Intravaginal Rings to HIV-Negative Women
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- Disruption of Tight Junctions by Cellulose Sulfate Facilitates HIV Infection: Model of Microbicide Safety
- (2009) Pedro M. M. Mesquita et al. JOURNAL OF INFECTIOUS DISEASES
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