Two into one does go: Formulation development of a multipurpose combination vaginal ring releasing dapivirine and metronidazole for prevention of HIV infection and treatment of bacterial vaginosis
出版年份 2023 全文链接
标题
Two into one does go: Formulation development of a multipurpose combination vaginal ring releasing dapivirine and metronidazole for prevention of HIV infection and treatment of bacterial vaginosis
作者
关键词
-
出版物
International Journal of Pharmaceutics
Volume -, Issue -, Pages 123572
出版商
Elsevier BV
发表日期
2023-11-04
DOI
10.1016/j.ijpharm.2023.123572
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Expanding the pipeline for multipurpose prevention technologies: compounds with potential activity to prevent or treat HIV and other STIs
- (2023) Bethany Young Holt et al. SEXUALLY TRANSMITTED INFECTIONS
- Physicochemical considerations in the formulation development of silicone elastomer vaginal rings releasing 5-nitroimidazole drugs for the treatment of bacterial vaginosis
- (2023) Xinyu Zhao et al. International Journal of Pharmaceutics
- A review of liquid silicone rubber injection molding: Process variables and process modeling
- (2021) Matthew Bont et al. POLYMER ENGINEERING AND SCIENCE
- Safety, adherence, and HIV-1 seroconversion among women using the dapivirine vaginal ring (DREAM): an open-label, extension study
- (2021) Annalene Nel et al. Lancet HIV
- Phase 1 pharmacokinetics and safety study of extended duration dapivirine vaginal rings in the United States
- (2021) Albert Y Liu et al. Journal of the International AIDS Society
- Impact of Dapivirine and Placebo Vaginal Rings on the Microbiota of Adolescent, Lactating, and Postmenopausal Females
- (2021) Michele N Austin et al. JOURNAL OF INFECTIOUS DISEASES
- Sink conditions do not guarantee the absence of saturation effects
- (2020) J. Siepmann et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The ins and outs of drug-releasing vaginal rings: a literature review of expulsions and removals
- (2020) Peter Boyd et al. Expert Opinion on Drug Delivery
- Mechanical testing methods for drug-releasing vaginal rings
- (2019) Clare F. McCoy et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- High Global Burden and Costs of Bacterial Vaginosis
- (2019) Kathryn Peebles et al. SEXUALLY TRANSMITTED DISEASES
- Antimicrobial and inflammatory properties of South African clinical Lactobacillus isolates and vaginal probiotics
- (2019) Emily Chetwin et al. Scientific Reports
- Vaginal rings with exposed cores for sustained delivery of the HIV CCR5 inhibitor 5P12-RANTES
- (2019) John W. McBride et al. JOURNAL OF CONTROLLED RELEASE
- The development of a silicone vaginal ring with a prostaglandin analogue for potential use in the treatment of canine reproductive disorders
- (2019) Veronika Nováková Tkadlečková et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Post-use ring weight and residual drug content as potential objective measures of user adherence to a contraceptive progesterone vaginal ring
- (2019) Diarmaid J. Murphy et al. CONTRACEPTION
- Drug stability and product performance characteristics of a dapivirine-releasing vaginal ring under simulated real-world conditions
- (2019) Diarmaid J. Murphy et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Towards a dapivirine and levonorgestrel multipurpose vaginal ring: Investigations into the reaction between levonorgestrel and addition-cure silicone elastomers
- (2019) Yahya H. Dallal Bashi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- How tenofovir disoproxil fumarate can impact on solubility and dissolution rate of efavirenz?
- (2019) Giovana Carolina Bazzo et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Vaginal microbiota and susceptibility to HIV
- (2018) McKenna C. Eastment et al. AIDS
- Solid state 13 C NMR spectroscopy provides direct evidence for reaction between ethinyl estradiol and a silicone elastomer vaginal ring drug delivery system
- (2018) Clare F. McCoy et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The Tablets, Ring, Injections as Options (TRIO) study: what young African women chose and used for future HIV and pregnancy prevention
- (2018) Ariane van der Straten et al. Journal of the International AIDS Society
- Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid
- (2018) David Tyssen et al. mSphere
- OUP accepted manuscript
- (2018) CLINICAL INFECTIOUS DISEASES
- Lactobacillus -Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women
- (2017) Christina Gosmann et al. IMMUNITY
- Experts explore the state of bacterial vaginosis and the unmet needs facing women and providers
- (2017) Steven E. Chavoustie et al. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
- Enhancement of dissolution rate through eutectic mixture and solid solution of posaconazole and benznidazole
- (2017) Camila Bezerra Melo Figueirêdo et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Packing Polymorphism of Dapivirine and Its Impact on the Performance of a Dapivirine-Releasing Silicone Elastomer Vaginal Ring
- (2017) Clare F. McCoy et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition
- (2017) A C Hearps et al. Mucosal Immunology
- Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women
- (2017) Nichole R. Klatt et al. SCIENCE
- Microbicide vaginal rings: Technological challenges and clinical development
- (2016) R. Karl Malcolm et al. ADVANCED DRUG DELIVERY REVIEWS
- Bacterial vaginosis: a critical analysis of current knowledge
- (2016) D Nasioudis et al. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
- Microbiome alterations in HIV infection a review
- (2016) Brett Williams et al. CELLULAR MICROBIOLOGY
- Parameterising User Uptake in Economic Evaluations: The role of discrete choice experiments
- (2016) Fern Terris-Prestholt et al. HEALTH ECONOMICS
- Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel
- (2016) Peter Boyd et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Controlling levonorgestrel binding and release in a multi-purpose prevention technology vaginal ring device
- (2016) Diarmaid J. Murphy et al. JOURNAL OF CONTROLLED RELEASE
- Post-use assay of vaginal rings (VRs) as a potential measure of clinical trial adherence
- (2016) Patrick Spence et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Safety and Efficacy of a Dapivirine Vaginal Ring for HIV Prevention in Women
- (2016) Annalene Nel et al. NEW ENGLAND JOURNAL OF MEDICINE
- Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women
- (2016) Jared M. Baeten et al. OBSTETRICAL & GYNECOLOGICAL SURVEY
- Genital Inflammation and the Risk of HIV Acquisition in Women
- (2015) Lindi Masson et al. CLINICAL INFECTIOUS DISEASES
- Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins and an influx of HIV-susceptible target cells
- (2015) Kelly B Arnold et al. Mucosal Immunology
- A safety and pharmacokinetic trial assessing delivery of dapivirine from a vaginal ring in healthy women
- (2014) Annalene Nel et al. AIDS
- Beyond HIV microbicides: multipurpose prevention technology products
- (2014) RK Malcolm et al. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
- Advanced topical drug delivery system for the management of vaginal candidiasis
- (2014) Himmat Singh Johal et al. DRUG DELIVERY
- Pre-clinical development of a combination microbicide vaginal ring containing dapivirine and darunavir
- (2014) Diarmaid J. Murphy et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- DSC study and calculation of metronidazole and clarithromycin thermodynamic melting parameters for individual substances and for eutectic mixture
- (2014) Evgeniia V. Agafonova et al. THERMOCHIMICA ACTA
- Development of dapivirine vaginal ring for HIV prevention
- (2013) Bríd Devlin et al. ANTIVIRAL RESEARCH
- Vaginal concentrations of lactic acid potently inactivate HIV
- (2013) Muriel Aldunate et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Sustained Release of the CCR5 Inhibitors CMPD167 and Maraviroc from Vaginal Rings in Rhesus Macaques
- (2012) R. Karl Malcolm et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of action
- (2012) Susan M. Fetherston et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- An Intravaginal Ring for the Simultaneous Delivery of Multiple Drugs
- (2012) Marc M. Baum et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Higuchi equation: Derivation, applications, use and misuse
- (2011) Juergen Siepmann et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Effect of the incorporation of hydroxy-terminated liquid silicones on the cure characteristics, morphology, and release of a model protein from silicone elastomer-covered rods
- (2011) Christopher McConville et al. JOURNAL OF APPLIED POLYMER SCIENCE
- Rheological evaluation of the isothermal cure characteristics of medical grade silicone elastomers
- (2010) Christopher McConville et al. JOURNAL OF APPLIED POLYMER SCIENCE
- Safety and Availability of Dapivirine (TMC120) Delivered from an Intravaginal Ring
- (2009) J. Romano et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Safety and Pharmacokinetics of Dapivirine Delivery From Matrix and Reservoir Intravaginal Rings to HIV-Negative Women
- (2009) Annalene Nel et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Disruption of Tight Junctions by Cellulose Sulfate Facilitates HIV Infection: Model of Microbicide Safety
- (2009) Pedro M. M. Mesquita et al. JOURNAL OF INFECTIOUS DISEASES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started