An In Silico Study for Expanding the Utility of Cannabidiol in Alzheimer’s Disease Therapeutic Development

Cannabinoids in neuroinflammatory disorders: Focusing on multiple sclerosis, Parkinsons, and Alzheimers diseases

(2023) Bahareh Abd‐Nikfarjam et al.   BIOFACTORS

CIRCE: Web-Based Platform for the Prediction of Cannabinoid Receptor Ligands Using Explainable Machine Learning

(2023) Nicola Gambacorta et al.   Journal of Chemical Information and Modeling

A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

(2022) Jiangling Peng et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Recent Advances on Type-2 Cannabinoid (CB2) Receptor Agonists and Their Therapeutic Potential

(2022) Valeria Gasperi et al.   CURRENT MEDICINAL CHEMISTRY

New cannabidiol (CBD) derivatives: Synthesis, anti-inflammatory activity, and molecular docking

(2022) Cheng-Ting Zi et al.   Phytochemistry Letters

Cannabidiol as a Therapeutic Target: Evidence of its Neuroprotective and Neuromodulatory Function in Parkinson’s Disease

(2021) Felipe Patricio et al.   Frontiers in Pharmacology

De novo design of new chemical entities for SARS-CoV-2 using artificial intelligence

(2021) Navneet Bung et al.   Future Medicinal Chemistry

Roles of Cannabidiol in the treatment and prevention of Alzheimer’s disease by multi-target actions

(2021) Xiao- Bei Zhang et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Investigation of the Multi-Target Mechanism of Guanxin-Shutong Capsule in Cerebrovascular Diseases: A Systems Pharmacology and Experimental Assessment

(2021) Juanli Zhang et al.   Frontiers in Pharmacology

Computational insights into binding mechanism of drugs as potential inhibitors against SARS-CoV-2 targets

(2021) Mahreen Arooj et al.   CHEMICAL PAPERS

Understanding the Modulatory Effects of Cannabidiol on Alzheimer’s Disease

(2021) Yinyi Xiong et al.   Brain Sciences

Molecular Simulation Study on the Interaction between Tyrosinase and Flavonoids from Sea Buckthorn

(2021) Xiaofang Li et al.   ACS Omega

Virtual screening using docking and molecular dynamics of cannabinoid analogs against CB1 and CB2 receptors

(2021) Antistio Aviz-Amador et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Activation of GPR55 attenuates cognitive impairment and neurotoxicity in a mouse model of Alzheimer's disease induced by Aβ1–42 through inhibiting RhoA/ROCK2 pathway

(2021) XiaoTong Xiang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

From Cannabis sativa to Cannabidiol: Promising Therapeutic Candidate for the Treatment of Neurodegenerative Diseases

(2020) Tommaso Cassano et al.   Frontiers in Pharmacology

Overview of cannabidiol (CBD) and its analogues: Structures, biological activities, and neuroprotective mechanisms in epilepsy and Alzheimer’s disease

(2020) Han Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions

(2020) Mengyu Liu et al.   Scientific Reports

Emerging potential of cannabidiol in reversing proteinopathies

(2020) Raju Dash et al.   AGEING RESEARCH REVIEWS

DeepPurpose: a deep learning library for drug–target interaction prediction

(2020) Kexin Huang et al.   BIOINFORMATICS

Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders

(2020) María S. García-Gutiérrez et al.   Biomolecules

Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer

(2019) Andrew M. Petros et al.   JOURNAL OF MEDICINAL CHEMISTRY

PrankWeb: a web server for ligand binding site prediction and visualization

(2019) Lukas Jendele et al.   NUCLEIC ACIDS RESEARCH

GPR3, GPR6, and GPR12 as novel molecular targets: their biological functions and interaction with cannabidiol

(2018) Alyssa S. Laun et al.   ACTA PHARMACOLOGICA SINICA

Anti-Amyloid-β Monoclonal Antibodies for Alzheimer’s Disease: Pitfalls and Promise

(2018) Christopher H. van Dyck   BIOLOGICAL PSYCHIATRY

Allosteric and orthosteric pharmacology of cannabidiol and cannabidiol-dimethylheptyl at the type 1 and type 2 cannabinoid receptors

(2018) Mylyne Tham et al.   BRITISH JOURNAL OF PHARMACOLOGY

Population-based De Novo Molecule Generation, Using Grammatical Evolution

(2018) Naruki Yoshikawa et al.   CHEMISTRY LETTERS

In Silico Identification of Novel Apolipoprotein E4 Inhibitor for Alzheimer’s Disease Therapy

(2018) Saddia Bano et al.   Current Computer-Aided Drug Design

UniProt: a worldwide hub of protein knowledge

(2018)   NUCLEIC ACIDS RESEARCH

OUP accepted manuscript

(2017)   NUCLEIC ACIDS RESEARCH

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Analysis of natural product regulation of cannabinoid receptors in the treatment of human disease

(2017) S. Badal et al.   PHARMACOLOGY & THERAPEUTICS

Protein-Ligand Blind Docking Using QuickVina-W With Inter-Process Spatio-Temporal Integration

(2017) Nafisa M. Hassan et al.   Scientific Reports

In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease

(2017) Georgia Watt et al.   Frontiers in Pharmacology

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

Cannabidiol (CBD) and its analogs: a review of their effects on inflammation

(2015) Sumner Burstein   BIOORGANIC & MEDICINAL CHEMISTRY

Cannabinoids for Medical Use

(2015) Penny F. Whiting et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Isolation and Pharmacological Evaluation of Minor Cannabinoids from High-Potency Cannabis sativa

(2015) Mohamed M. Radwan et al.   JOURNAL OF NATURAL PRODUCTS

A unified lead-oriented synthesis of over fifty molecular scaffolds

(2015) Richard G. Doveston et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Inhibition of myeloperoxidase activity by the alkaloids of Peganum harmala L. (Zygophyllaceae)

(2014) Sihem Bensalem et al.   JOURNAL OF ETHNOPHARMACOLOGY

OMIM.org: Online Mendelian Inheritance in Man (OMIM®), an online catalog of human genes and genetic disorders

(2014) Joanna S. Amberger et al.   NUCLEIC ACIDS RESEARCH

Oxidative stress in Alzheimer’s disease

(2014) Zhichun Chen et al.   Neuroscience Bulletin

Quantifying the chemical beauty of drugs

(2012) G. Richard Bickerton et al.   Nature Chemistry

Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death

(2011) Partha Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

(2010) Jonathan B. Baell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Optimized Hydrophobic Interactions and Hydrogen Bonding at the Target-Ligand Interface Leads the Pathways of Drug-Designing

(2010) Rohan Patil et al.   PLoS One

Engineering a Ubiquitin Ligase Reveals Conformational Flexibility Required for Ubiquitin Transfer

(2009) Shu-Bing Qian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estimation of synthetic accessibility score of drug-like molecules based on molecular complexity and fragment contributions

(2009) Peter Ertl et al.   Journal of Cheminformatics

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro

(2007) A Thomas et al.   BRITISH JOURNAL OF PHARMACOLOGY