From Cannabis sativa to Cannabidiol: Promising Therapeutic Candidate for the Treatment of Neurodegenerative Diseases
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Title
From Cannabis sativa to Cannabidiol: Promising Therapeutic Candidate for the Treatment of Neurodegenerative Diseases
Authors
Keywords
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Journal
Frontiers in Pharmacology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-03-07
DOI
10.3389/fphar.2020.00124
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Note: Only part of the references are listed.- Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-TH1A and TRPV1 receptor mechanisms
- (2019) Ewa Galaj et al. NEUROPHARMACOLOGY
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- (2018) Vanessa Kappel da Silva et al. BRAIN RESEARCH BULLETIN
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- (2018) Agnese Gugliandolo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2018) Anna Maria Giudetti et al. Oxidative Medicine and Cellular Longevity
- Palmitoylethanolamide Dampens Reactive Astrogliosis and Improves Neuronal Trophic Support in a Triple Transgenic Model of Alzheimer’s Disease: In Vitro and In Vivo Evidence
- (2018) Maria Rosanna Bronzuoli et al. Oxidative Medicine and Cellular Longevity
- Ultramicronized palmitoylethanolamide rescues learning and memory impairments in a triple transgenic mouse model of Alzheimer’s disease by exerting anti-inflammatory and neuroprotective effects
- (2018) Caterina Scuderi et al. Translational Psychiatry
- Altered Expression of the CB1 Cannabinoid Receptor in the Triple Transgenic Mouse Model of Alzheimer's Disease
- (2018) Gaurav Bedse et al. JOURNAL OF ALZHEIMERS DISEASE
- Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer
- (2018) Federica Pellati et al. Biomed Research International
- Linking lipid peroxidation and neuropsychiatric disorders: focus on 4-hydroxy-2-nonenal
- (2017) Adele Romano et al. FREE RADICAL BIOLOGY AND MEDICINE
- GPR55: A therapeutic target for Parkinson's disease?
- (2017) Marta Celorrio et al. NEUROPHARMACOLOGY
- Cannabinoid Receptor 2 Signaling in Neurodegenerative Disorders: From Pathogenesis to a Promising Therapeutic Target
- (2017) Tommaso Cassano et al. Frontiers in Neuroscience
- An update on PPAR activation by cannabinoids
- (2016) Saoirse Elizabeth O'Sullivan BRITISH JOURNAL OF PHARMACOLOGY
- Cannabidiol protects an in vitro model of the blood-brain barrier from oxygen-glucose deprivation via PPARγ and 5-HT1A receptors
- (2016) William H Hind et al. BRITISH JOURNAL OF PHARMACOLOGY
- Glutamate and Mitochondria: Two Prominent Players in the Oxidative Stress-Induced Neurodegeneration
- (2016) Tommaso Cassano et al. Current Alzheimer Research
- Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial
- (2016) Orrin Devinsky et al. LANCET NEUROLOGY
- Cannabidiol, neuroprotection and neuropsychiatric disorders
- (2016) Alline C. Campos et al. PHARMACOLOGICAL RESEARCH
- Unknown
- (2015) Enkui Hao et al. MOLECULAR MEDICINE
- Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats
- (2015) A.A. Martinez et al. NEUROBIOLOGY OF DISEASE
- 5-S-cysteinyldopamine neurotoxicity: Influence on the expression of α-synuclein and ERp57 in cellular and animal models of Parkinson's disease
- (2013) Cristina Aureli et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?
- (2012) Javier Fernández-Ruiz et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- GPR18 in microglia: implications for the CNS and endocannabinoid system signalling
- (2012) D McHugh BRITISH JOURNAL OF PHARMACOLOGY
- Endocannabinoid tone versus constitutive activity of cannabinoid receptors
- (2011) Allyn C. Howlett et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabinoids: Occurrence and Medicinal Chemistry
- (2011) G. Appendino et al. CURRENT MEDICINAL CHEMISTRY
- Principles and Therapeutic Relevance for Targeting Mitochondria in Aging and Neurodegenerative Diseases
- (2011) Gaetano Serviddio et al. CURRENT PHARMACEUTICAL DESIGN
- Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress
- (2011) George W. Booz FREE RADICAL BIOLOGY AND MEDICINE
- Cannabidiol and Other Cannabinoids Reduce Microglial Activation In Vitro and In Vivo: Relevance to Alzheimer's Disease
- (2011) A. M. Martin-Moreno et al. MOLECULAR PHARMACOLOGY
- Glutamatergic alterations and mitochondrial impairment in a murine model of Alzheimer disease
- (2011) Tommaso Cassano et al. NEUROBIOLOGY OF AGING
- Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement
- (2011) Giuseppe Esposito et al. PLoS One
- N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor
- (2010) Douglas McHugh et al. BMC NEUROSCIENCE
- Current Treatment and Recent Clinical Research in Alzheimer's Disease
- (2010) Judith Neugroschl et al. MOUNT SINAI JOURNAL OF MEDICINE
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Drug development for Alzheimer's disease: Where are we now and where are we headed?
- (2009) Marwan N. Sabbagh American Journal Geriatric Pharmacotherapy
- Striatal 6-OHDA lesion in mice: Investigating early neurochemical changes underlying Parkinson's disease
- (2009) Igor Branchi et al. BEHAVIOURAL BRAIN RESEARCH
- 5-HT1Areceptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats
- (2009) Leonardo B.M. Resstel et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabidiol: A Promising Drug for Neurodegenerative Disorders?
- (2009) Teresa Iuvone et al. CNS Neuroscience & Therapeutics
- Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options
- (2009) Bayani Uttara et al. Current Neuropharmacology
- Time-dependent vascular actions of cannabidiol in the rat aorta
- (2009) Saoirse E. O'Sullivan et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Mechanisms of brain iron transport: insight into neurodegeneration and CNS disorders
- (2009) Eric Mills et al. Future Medicinal Chemistry
- Cannabinoid activation of peroxisome proliferator-activated receptors: Potential for modulation of inflammatory disease
- (2009) S.E. O'Sullivan et al. IMMUNOBIOLOGY
- Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation
- (2009) Iddo Magen et al. JOURNAL OF HEPATOLOGY
- Δ9-Tetrahydrocannabinol and cannabidiol modulate mitogen-induced tryptophan degradation and neopterin formation in peripheral blood mononuclear cells in vitro
- (2009) Marcel Jenny et al. JOURNAL OF NEUROIMMUNOLOGY
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- (2009) D. Ryan et al. JOURNAL OF NEUROSCIENCE
- Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb
- (2009) Angelo A. Izzo et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Effects of Δ9-tetrahydrocannabivarin on [35S]GTPγS binding in mouse brain cerebellum and piriform cortex membranes
- (2008) I Dennis et al. BRITISH JOURNAL OF PHARMACOLOGY
- The phytocannabinoid Δ9-tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum
- (2008) Y-L Ma et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabidiolic Acid as a Selective Cyclooxygenase-2 Inhibitory Component in Cannabis
- (2008) S. Takeda et al. DRUG METABOLISM AND DISPOSITION
- Plant-Derived Cannabinoids Modulate the Activity of Transient Receptor Potential Channels of Ankyrin Type-1 and Melastatin Type-8
- (2008) L. De Petrocellis et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Targeting the endocannabinoid system: to enhance or reduce?
- (2008) Vincenzo Di Marzo NATURE REVIEWS DRUG DISCOVERY
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- Should peripheral CB1 cannabinoid receptors be selectively targeted for therapeutic gain?
- (2008) George Kunos et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin
- (2007) R G Pertwee BRITISH JOURNAL OF PHARMACOLOGY
- Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors
- (2007) S E O'Sullivan BRITISH JOURNAL OF PHARMACOLOGY
- Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression
- (2007) G Esposito et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro
- (2007) A Thomas et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabinoid pharmacology: the first 66 years
- (2006) Roger G Pertwee BRITISH JOURNAL OF PHARMACOLOGY
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