Interrogating the Role of miR-125b and Its 3′isomiRs in Protection against Hypoxia

Hairpin sequence and structure is associated with features of isomiR biogenesis

(2021) Anton Zhiyanov et al.   RNA Biology

The MicroRNA Family Gets Wider: The IsomiRs Classification and Role

(2021) Luisa Tomasello et al.   Frontiers in Cell and Developmental Biology

MiR-125 Family in Cardiovascular and Cerebrovascular Diseases

(2021) Yang Wang et al.   Frontiers in Cell and Developmental Biology

3′ Uridylation Confers miRNAs with Non-canonical Target Repertoires

(2019) Acong Yang et al.   MOLECULAR CELL

Global analyses of the dynamics of mammalian microRNA metabolism

(2019) Elena Kingston et al.   GENOME RESEARCH

MicroRNA-221 Is Cardioprotective and Anti-fibrotic in a Rat Model of Myocardial Infarction

(2019) Yue Zhou et al.   Molecular Therapy-Nucleic Acids

MicroRNA-411 and Its 5′-IsomiR Have Distinct Targets and Functions and Are Differentially Regulated in the Vasculature under Ischemia

(2019) Reginald V.C.T. van der Kwast et al.   MOLECULAR THERAPY

A Comprehensive Approach to Sequence-oriented IsomiR annotation (CASMIR): demonstration with IsomiR profiling in colorectal neoplasia

(2018) Chung Wah Wu et al.   BMC GENOMICS

A carvedilol-responsive microRNA, miR-125b-5p protects the heart from acute myocardial infarction by repressing pro-apoptotic bak1 and klf13 in cardiomyocytes

(2018) Ahmed S. Bayoumi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Knowledge about the presence or absence of miRNA isoforms (isomiRs) can successfully discriminate amongst 32 TCGA cancer types

(2017) Aristeidis G. Telonis et al.   NUCLEIC ACIDS RESEARCH

Naturally existing isoforms of miR-222 have distinct functions

(2017) Feng Yu et al.   NUCLEIC ACIDS RESEARCH

3′ Uridylation controls mature microRNA turnover during CD4 T-cell activation

(2017) Cristina Gutiérrez-Vázquez et al.   RNA

Characterization and Standardization of Cultured Cardiac Fibroblasts for Ex Vivo Models of Heart Fibrosis and Heart Ischemia

(2017) Yue Zhou et al.   TISSUE ENGINEERING PART C-METHODS

Identification of novel microRNAs in the sheep heart and their regulation in heart failure

(2017) Lee Lee Wong et al.   Scientific Reports

Deep sequencing and analyses of miRNAs, isomiRs and miRNA induced silencing complex (miRISC)-associated miRNome in primary human chondrocytes

(2017) Abdul Haseeb et al.   Scientific Reports

The transcardiac gradient of cardio-microRNAs in the failing heart

(2016) Francine Z. Marques et al.   EUROPEAN JOURNAL OF HEART FAILURE

MicroRNAs in Cardiovascular Disease

(2016) Temo Barwari et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Sequence Features of Drosha and Dicer Cleavage Sites Affect the Complexity of IsomiRs

(2015) Julia Starega-Roslan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Beyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity

(2015) Aristeidis G. Telonis et al.   NUCLEIC ACIDS RESEARCH

IsomiR expression profiles in human lymphoblastoid cell lines exhibit population and gender dependencies

(2015) Phillipe Loher et al.   Oncotarget

MicroRNA-125b protects against myocardial ischaemia/reperfusion injury via targeting p53-mediated apoptotic signalling and TRAF6

(2014) Xiaohui Wang et al.   CARDIOVASCULAR RESEARCH

5′ isomiR variation is of functional and evolutionary importance

(2014) Geok Chin Tan et al.   NUCLEIC ACIDS RESEARCH

mTORC2 Phosphorylation of Akt1: A Possible Mechanism for Hydrogen Sulfide-Induced Cardioprotection

(2014) Yue Zhou et al.   PLoS One

PAPD5-mediated 3' adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease

(2014) J. Boele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles

(2012) Eva van Rooij et al.   NATURE REVIEWS DRUG DISCOVERY

IsomiRs – the overlooked repertoire in the dynamic microRNAome

(2012) Corine T. Neilsen et al.   TRENDS IN GENETICS

MiR-125b promotes proliferation and migration of type II endometrial carcinoma cells through targeting TP53INP1 tumor suppressor in vitro and in vivo

(2011) Feizhou Jiang et al.   BMC CANCER

Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity

(2011) S. K. Wyman et al.   GENOME RESEARCH

MicroRNAs and their isomiRs function cooperatively to target common biological pathways

(2011) Nicole Cloonan et al.   GENOME BIOLOGY

A myriad of miRNA variants in control and Huntington’s disease brain regions detected by massively parallel sequencing

(2010) Eulàlia Martí et al.   NUCLEIC ACIDS RESEARCH

Zcchc11-dependent uridylation of microRNA directs cytokine expression

(2009) Matthew R. Jones et al.   NATURE CELL BIOLOGY