Deep sequencing and analyses of miRNAs, isomiRs and miRNA induced silencing complex (miRISC)-associated miRNome in primary human chondrocytes

MicroRNA-99a regulates early chondrogenic differentiation of rat mesenchymal stem cells by targeting the BMPR2 gene

(2016) Xiaozhong Zhou et al.   CELL AND TISSUE RESEARCH

Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP

(2016) Ryan M. Spengler et al.   NUCLEIC ACIDS RESEARCH

High-resolution analysis of the human retina miRNome reveals isomiR variations and novel microRNAs

(2016) Marianthi Karali et al.   NUCLEIC ACIDS RESEARCH

Detecting new microRNAs in human osteoarthritic chondrocytes identifies miR-3085 as a human, chondrocyte-selective, microRNA

(2016) N. Crowe et al.   OSTEOARTHRITIS AND CARTILAGE

Identification of synovial fluid microRNA signature in knee osteoarthritis: differentiating early- and late-stage knee osteoarthritis

(2016) Y.-H. Li et al.   OSTEOARTHRITIS AND CARTILAGE

Identification of miRNomes associated with adult neurogenesis after stroke using Argonaute 2-based RNA sequencing

(2016) Xian Shuang Liu et al.   RNA Biology

Arm Selection Preference of MicroRNA-193a Varies in Breast Cancer

(2016) Kuo-Wang Tsai et al.   Scientific Reports

Expression of microRNAs and isomiRs in the porcine endometrium: implications for gene regulation at the maternal-conceptus interface

(2015) Kamil Krawczynski et al.   BMC GENOMICS

The Role of miRNAs in Cartilage Homeostasis

(2015) Yong Li et al.   CURRENT GENOMICS

Beyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity

(2015) Aristeidis G. Telonis et al.   NUCLEIC ACIDS RESEARCH

Identification of the miRNA targetome in hippocampal neurons using RIP-seq

(2015) Josephine Malmevik et al.   Scientific Reports

Bacterial Infection Drives the Expression Dynamics of microRNAs and Their isomiRs

(2015) Katherine J. Siddle et al.   PLoS Genetics

MicroRNA-9 Promotion of Interleukin-6 Expression by Inhibiting Monocyte Chemoattractant Protein-Induced Protein 1 Expression in Interleukin-1β-Stimulated Human Chondrocytes

(2015) Mohammad S. Makki et al.   Arthritis & Rheumatology

Genetic variants in microRNA genes: impact on microRNA expression, function, and disease

(2015) Sophia Cammaerts et al.   Frontiers in Genetics

Therapeutic targeting of microRNAs: current status and future challenges

(2014) Zhonghan Li et al.   NATURE REVIEWS DRUG DISCOVERY

5′ isomiR variation is of functional and evolutionary importance

(2014) Geok Chin Tan et al.   NUCLEIC ACIDS RESEARCH

Differential RISC association of endogenous human microRNAs predicts their inhibitory potential

(2014) Omar Flores et al.   NUCLEIC ACIDS RESEARCH

Nontemplated Nucleotide Additions Distinguish the Small RNA Composition in Cells from Exosomes

(2014) Danijela Koppers-Lalic et al.   Cell Reports

Review: The Role of MicroRNAs in Osteoarthritis and Chondrogenesis

(2013) Linh T. T. Le et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-92a Upholds Bmp Signaling by Targeting noggin3 during Pharyngeal Cartilage Formation

(2013) Guozhu Ning et al.   DEVELOPMENTAL CELL

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

miRNA arm selection and isomiR distribution in gastric cancer

(2012) Sung-Chou Li et al.   BMC GENOMICS

Macro view of microRNA function in osteoarthritis

(2012) Shigeru Miyaki et al.   Nature Reviews Rheumatology

IsomiRs – the overlooked repertoire in the dynamic microRNAome

(2012) Corine T. Neilsen et al.   TRENDS IN GENETICS

The role of the precursor structure in the biogenesis of microRNA

(2011) Julia Starega-Roslan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The 3′-to-5′ Exoribonuclease Nibbler Shapes the 3′ Ends of MicroRNAs Bound to Drosophila Argonaute1

(2011) Bo W. Han et al.   CURRENT BIOLOGY

MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis

(2011) Xin Li et al.   GENE

Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity

(2011) S. K. Wyman et al.   GENOME RESEARCH

Regulation of Human Chondrocyte Function through Direct Inhibition of Cartilage Master Regulator SOX9 by MicroRNA-145 (miRNA-145)

(2011) Aida Martinez-Sanchez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessment of the profiling MicroRNA expression of differentiated and dedifferentiated human adult articular chondrocytes

(2011) Lin Lin et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis

(2011) M. Kurowska-Stolarska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deep sequencing of microRNA precursors reveals extensive 3' end modification

(2011) M. A. Newman et al.   RNA

MicroRNAs and their isomiRs function cooperatively to target common biological pathways

(2011) Nicole Cloonan et al.   GENOME BIOLOGY

MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes

(2010) Nahid Akhtar et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-140 and the silencing of osteoarthritis

(2010) E. Araldi et al.   GENES & DEVELOPMENT

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

(2010) H. R. Chiang et al.   GENES & DEVELOPMENT

MicroRNA-140 plays dual roles in both cartilage development and homeostasis

(2010) S. Miyaki et al.   GENES & DEVELOPMENT

A comprehensive survey of 3' animal miRNA modification events and a possible role for 3' adenylation in modulating miRNA targeting effectiveness

(2010) A. M. Burroughs et al.   GENOME RESEARCH

Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence

(2010) E. Berezikov et al.   GENOME RESEARCH

A myriad of miRNA variants in control and Huntington’s disease brain regions detected by massively parallel sequencing

(2010) Eulàlia Martí et al.   NUCLEIC ACIDS RESEARCH

Pomegranate extract inhibits the interleukin-1β-induced activation of MKK-3, p38α-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes

(2010) Zafar Rasheed et al.   ARTHRITIS RESEARCH & THERAPY

Meta-analysis of small RNA-sequencing errors reveals ubiquitous post-transcriptional RNA modifications

(2009) H. Alexander Ebhardt et al.   NUCLEIC ACIDS RESEARCH

Alternative Processing of Primary microRNA Transcripts by Drosha Generates 5′ End Variation of Mature microRNA

(2009) Haoquan Wu et al.   PLoS One

Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies

(2008) Yan Zeng et al.   BIOCHEMICAL JOURNAL

Integrative MicroRNA and Proteomic Approaches Identify Novel Osteoarthritis Genes and Their Collaborative Metabolic and Inflammatory Networks

(2008) Dimitrios Iliopoulos et al.   PLoS One