Innate activation of human neutrophils and neutrophil-like cells by the pro-inflammatory bacterial metabolite ADP-heptose and Helicobacter pylori

Innate immune activation and modulatory factors of Helicobacter pylori towards phagocytic and nonphagocytic cells

(2023) Larissa Faass et al.   CURRENT OPINION IN IMMUNOLOGY

Helicobacter pylori Modulates Heptose Metabolite Biosynthesis and Heptose-Dependent Innate Immune Host Cell Activation by Multiple Mechanisms

(2023) Martina Hauke et al.   Microbiology Spectrum

A20 undermines alternative NF-κB activity and expression of anti-apoptotic genes in Helicobacter pylori infection

(2022) Michelle C. C. Lim et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The central inflammasome adaptor protein ASC activates the inflammasome after transition from a soluble to an insoluble state

(2022) Evan R. Prather et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

USP48 and A20 synergistically promote cell survival in Helicobacter pylori infection

(2022) Phatcharida Jantaree et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC

(2022) Tom Snelling et al.   BIOCHEMICAL JOURNAL

Helicobacter pylori-infected human neutrophils exhibit impaired chemotaxis and a uropod retraction defect

(2022) Allan Prichard et al.   Frontiers in Immunology

Tumor-associated myeloid cells: diversity and therapeutic targeting

(2021) Alberto Mantovani et al.   Cellular & Molecular Immunology

Chemotaxis and swarming in differentiated HL-60 neutrophil-like cells

(2021) Kehinde Adebayo Babatunde et al.   Scientific Reports

Contribution of Heptose Metabolites and the cag Pathogenicity Island to the Activation of Monocytes/Macrophages by Helicobacter pylori

(2021) Larissa Faass et al.   Frontiers in Immunology

TIFA has dual functions in Helicobacter pylori ‐induced classical and alternative NF‐κB pathways

(2021) Gunter Maubach et al.   EMBO REPORTS

ADP‐heptose enables Helicobacter pylori to exploit macrophages as a survival niche by suppressing antigen‐presenting HLA‐II expression

(2021) Sara Coletta et al.   FEBS LETTERS

The Neutrophil

(2021) Garth Lawrence Burn et al.   IMMUNITY

Indoleamine 2,3-Dioxygenase Cannot Inhibit Chlamydia trachomatis Growth in HL-60 Human Neutrophil Granulocytes

(2021) Dezső P. Virok et al.   Frontiers in Immunology

ADP-heptose: a bacterial PAMP detected by the host sensor ALPK1

(2020) Diego García-Weber et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress

(2020) Michael Bauer et al.   Nature Communications

ADP heptose, a novel pathogen-associated molecular pattern identified in Helicobacter pylori

(2019) Lennart Pfannkuch et al.   FASEB JOURNAL

Neutrophil Diversity in Health and Disease

(2019) Carlos Silvestre-Roig et al.   TRENDS IN IMMUNOLOGY

Neutrophil: A Cell with Many Roles in Inflammation or Several Cell Types?

(2018) Carlos Rosales   Frontiers in Physiology

A map of gene expression in neutrophil-like cell lines

(2018) Esther Rincón et al.   BMC GENOMICS

d-Glycero-β-d-Manno-Heptose 1-Phosphate and d-Glycero-β-d-Manno-Heptose 1,7-Biphosphate Are Both Innate Immune Agonists

(2018) Itunuoluwa A. Adekoya et al.   JOURNAL OF IMMUNOLOGY

Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose

(2018) Ping Zhou et al.   NATURE

The core genome m5C methyltransferase JHP1050 (M.Hpy99III) plays an important role in orchestrating gene expression in Helicobacter pylori

(2018) Iratxe Estibariz et al.   NUCLEIC ACIDS RESEARCH

The intra- and extracellular functions of ASC specks

(2017) Bernardo S Franklin et al.   IMMUNOLOGICAL REVIEWS

Cutting Edge:Helicobacter pyloriInduces Nuclear Hypersegmentation and Subtype Differentiation of Human Neutrophils In Vitro

(2017) Laura C. Whitmore et al.   JOURNAL OF IMMUNOLOGY

ALPK1- and TIFA-Dependent Innate Immune Response Triggered by the Helicobacter pylori Type IV Secretion System

(2017) Stephanie Zimmermann et al.   Cell Reports

ALPK1 controls TIFA/TRAF6-dependent innate immunity against heptose-1,7-bisphosphate of gram-negative bacteria

(2017) Milica Milivojevic et al.   PLoS Pathogens

Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis

(2017) Saskia C. Stein et al.   PLoS Pathogens

Transcriptomes reflect the phenotypes of undifferentiated, granulocyte and macrophage forms of HL-60/S4 cells

(2017) David B. Mark Welch et al.   Nucleus

Transcriptomes reflect the phenotypes of undifferentiated, granulocyte and macrophage forms of HL-60/S4 cells

(2017) David B. Mark Welch et al.   Nucleus

Current Understanding in Neutrophil Differentiation and Heterogeneity

(2017) Chang-Won Hong   Immune Network

Pathogenic Helicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system

(2016) M G Varga et al.   ONCOGENE

Aging: A Temporal Dimension for Neutrophils

(2016) José M. Adrover et al.   TRENDS IN IMMUNOLOGY

Different gastric microbiota compositions in two human populations with high and low gastric cancer risk in Colombia

(2016) Ines Yang et al.   Scientific Reports

Activation of NLRP3 inflammasome in human neutrophils by Helicobacter pylori infection

(2015) Erandi Pérez-Figueroa et al.   Innate Immunity

Cytosolic detection of the bacterial metabolite HBP activates TIFA-dependent innate immunity

(2015) R. G. Gaudet et al.   SCIENCE

TLR9 and NF-κB Are Partially Involved in Activation of Human Neutrophils by Helicobacter pylori and Its Purified DNA

(2014) Lourdes Alvarez-Arellano et al.   PLoS One

The Multifaceted Functions of Neutrophils

(2013) Tanya N. Mayadas et al.   Annual Review of Pathology-Mechanisms of Disease

Infection-Induced Changes in Hematopoiesis

(2013) A. G. Zaretsky et al.   JOURNAL OF IMMUNOLOGY

A Global Overview of the Genetic and Functional Diversity in the Helicobacter pylori cag Pathogenicity Island

(2010) Patrick Olbermann et al.   PLoS Genetics

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

(2009) Zvi G. Fridlender et al.   CANCER CELL

Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil differentiation of human leukaemia HL-60 cells

(2008) Faustino Mollinedo et al.   GENE

STRING 8--a global view on proteins and their functional interactions in 630 organisms

(2008) L. J. Jensen et al.   NUCLEIC ACIDS RESEARCH