Inhibition of GPR30 sensitized gefitinib to NSCLC cells via regulation of epithelial-mesenchymal transition

MiR-25 enhances autophagy and promotes sorafenib resistance of hepatocellular carcinoma via targeting FBXW7

(2022) Xiaoning Feng et al.   International Journal of Medical Sciences

FAM198B promotes colorectal cancer progression by regulating the polarization of tumor-associated macrophages via the SMAD2 signaling pathway

(2022) Xiaoxiao Zheng et al.   Bioengineered

HOTAIR/miR-1277-5p/ZEB1 axis mediates hypoxia-induced oxaliplatin resistance via regulating epithelial-mesenchymal transition in colorectal cancer

(2022) Xingyue Weng et al.   Cell Death Discovery

A novel combination treatment of antiADAM17 antibody and erlotinib to overcome acquired drug resistance in non-small cell lung cancer through the FOXO3a/FOXM1 axis

(2022) Junnan Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nanotechnology-based approaches overcome lung cancer drug resistance through diagnosis and treatment

(2022) Junnan Li et al.   DRUG RESISTANCE UPDATES

Cancer Statistics, 2021

(2021) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

EMT‐associated microRNAs and their roles in cancer stemness and drug resistance

(2021) Guangtao Pan et al.   Cancer Communications

Targeting STAT3 signaling overcomes gefitinib resistance in non-small cell lung cancer

(2021) Zhe Liu et al.   Cell Death & Disease

Cisplatin resistance in gastric cancer cells is involved with GPR30‐mediated epithelial‐mesenchymal transition

(2020) Xiaofeng Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Tepotinib plus gefitinib in patients with EGFR-mutant non-small-cell lung cancer with MET overexpression or MET amplification and acquired resistance to previous EGFR inhibitor (INSIGHT study): an open-label, phase 1b/2, multicentre, randomised trial

(2020) Yi-Long Wu et al.   Lancet Respiratory Medicine

GPER as a Receptor for Endocrine-Disrupting Chemicals (EDCs)

(2020) Séverine Périan et al.   Frontiers in Endocrinology

Role of GPER-Mediated Signaling in Testicular Functions and Tumorigenesis

(2020) Adele Chimento et al.   Cells

Recent Advances on the Role of EGFR Tyrosine Kinase Inhibitors in the Management of NSCLC With Uncommon, Non Exon 20 Insertions, EGFR Mutations

(2020) Antonio Passaro et al.   Journal of Thoracic Oncology

Interactions Between lncRNA TUG1 and miR-9-5p Modulate the Resistance of Breast Cancer Cells to Doxorubicin by Regulating eIF5A2

(2020) Shuqian Wang et al.   OncoTargets and Therapy

Activation of GPR30 with G1 attenuates neuronal apoptosis via src/EGFR/stat3 signaling pathway after subarachnoid hemorrhage in male rats

(2019) Jun Peng et al.   EXPERIMENTAL NEUROLOGY

The G protein-coupled estrogen receptor (GPER/GPR30) may serve as a prognostic marker in early-stage cervical cancer

(2017) Klaus Friese et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

G-Protein-Coupled Estrogen Receptor Antagonist G15 Decreases Estrogen-Induced Development of Non-Small Cell Lung Cancer

(2017) Changyu Liu et al.   ONCOLOGY RESEARCH

Estradiol promotes epithelial-to-mesenchymal transition in human benign prostatic epithelial cells

(2017) Xiaoyu Shi et al.   PROSTATE

TopBP1 contributes to the chemoresistance in non-small cell lung cancer through upregulation of p53

(2016) Yinxiang Lv et al.   Drug Design Development and Therapy

Estrogen and pure antiestrogen fulvestrant (ICI 182 780) augment cell–matrigel adhesion of MCF-7 breast cancer cells through a novel G protein coupled estrogen receptor (GPR30)-to-calpain signaling axis

(2014) Yan Chen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

G15, a GPR30 antagonist, induces apoptosis and autophagy in human oral squamous carcinoma cells

(2013) Li-Yuan Bai et al.   CHEMICO-BIOLOGICAL INTERACTIONS

A Multiplex qPCR Gene Dosage Assay for Rapid Genotyping and Large-Scale Population Screening for Deletional α-Thalassemia

(2013) Wanjun Zhou et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF

(2009) Deo Prakash Pandey et al.   EMBO JOURNAL

GPR30 predicts poor survival for ovarian cancer

(2009) Harriet O. Smith et al.   GYNECOLOGIC ONCOLOGY

Estrogen Signaling through the Transmembrane G Protein–Coupled Receptor GPR30

(2008) Eric R. Prossnitz et al.   Annual Review of Physiology