Interactions Between lncRNA TUG1 and miR-9-5p Modulate the Resistance of Breast Cancer Cells to Doxorubicin by Regulating eIF5A2

Recessive Rare Variants in Deoxyhypusine Synthase, an Enzyme Involved in the Synthesis of Hypusine, Are Associated with a Neurodevelopmental Disorder

(2019) Mythily Ganapathi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Chemotherapy-induced extracellular vesicle miRNAs promote breast cancer stemness by targeting ONECUT2

(2019) Meng Shen et al.   CANCER RESEARCH

Polydatin inhibits proliferation and promotes apoptosis of doxorubicin-resistant osteosarcoma through LncRNA TUG1 mediated suppression of Akt signaling

(2019) Tongzhou Hu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

An integrative bioinformatics analysis identified miR-375 as a candidate key regulator of malignant breast cancer

(2019) Jiaxuan Liu et al.   JOURNAL OF APPLIED GENETICS

lncRNA TUG1 Promotes Cisplatin Resistance by Regulating CCND2 via Epigenetically Silencing miR-194-5p in Bladder Cancer

(2019) Gan Yu et al.   Molecular Therapy-Nucleic Acids

LncRNA TUG1 promotes cells proliferation and inhibits cells apoptosis through regulating AURKA in epithelial ovarian cancer cells

(2018) Tonghuai Li et al.   MEDICINE

TUG1 confers Adriamycin resistance in acute myeloid leukemia by epigenetically suppressing miR-34a expression via EZH2

(2018) Qun Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Identification of dysregulated miRNAs in triple negative breast cancer: A meta-analysis approach

(2018) Leimarembi Devi Naorem et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2

(2017) Yuchun Niu et al.   Molecular Cancer

Stepwise analysis of MIR9 loci identifies miR-9-5p to be involved in Oestrogen regulated pathways in breast cancer patients

(2017) Raffaela Barbano et al.   Scientific Reports

Mg(II)-Catechin nanoparticles delivering siRNA targeting EIF5A2 inhibit bladder cancer cell growth in vitro and in vivo

(2016) Zhenhua Chen et al.   BIOMATERIALS

Eukaryotic translation initiation factor 5A2 promotes metabolic reprogramming in hepatocellular carcinoma cells

(2016) Ting-Ting Cao et al.   CARCINOGENESIS

Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment

(2016) Keisuke Katsushima et al.   Nature Communications

The translation factor eIF5A and human cancer

(2015) Michael B. Mathews et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

N1-Guanyl-1,7-Diaminoheptane Sensitizes Estrogen Receptor Negative Breast Cancer Cells to Doxorubicin by Preventing Epithelial-Mesenchymal Transition through Inhibition of Eukaryotic Translation Initiation Factor 5A2 Activation

(2015) Yu Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

Upregulation of long non-coding RNA TUG1 correlates with poor prognosis and disease status in osteosarcoma

(2015) Bing Ma et al.   TUMOR BIOLOGY

EphA6 promotes angiogenesis and prostate cancer metastasis and is associated with human prostate cancer progression

(2015) Shibao Li et al.   Oncotarget

Development, Maintenance, and Reversal of Multiple Drug Resistance: At the Crossroads of TFPI1, ABC Transporters, and HIF1

(2015) Terra Arnason et al.   Cancers

Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer

(2015) Ehsan Malek et al.   Oncotarget

Increased Expression of EIF5A2, Via Hypoxia or Gene Amplification, Contributes to Metastasis and Angiogenesis of Esophageal Squamous Cell Carcinoma

(2014) Yan Li et al.   GASTROENTEROLOGY

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

EIF5A2 is a novel chemoresistance gene in breast cancer

(2014) Yu Liu et al.   Breast Cancer

P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression

(2014) E-b Zhang et al.   Cell Death & Disease

lincRNAs: Genomics, Evolution, and Mechanisms

(2013) Igor Ulitsky et al.   CELL

Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder

(2012) Yonghua Han et al.   JOURNAL OF SURGICAL ONCOLOGY

ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs

(2011) Liuqing Yang et al.   CELL

Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce epithelial–mesenchymaltransition

(2011) Wei Zhu et al.   GUT

Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma

(2009) Dong-Jiang Tang et al.   HEPATOLOGY

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Oncogenomics-Based In Vivo RNAi Screen Identifies Tumor Suppressors in Liver Cancer

(2008) Lars Zender et al.   CELL

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS