Novel phenanthrene imidazoles as telomeric G-quadruplex ligands trigger potent immunogenic cell death in triple-negative breast cancer
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Title
Novel phenanthrene imidazoles as telomeric G-quadruplex ligands trigger potent immunogenic cell death in triple-negative breast cancer
Authors
Keywords
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Journal
International Journal of Biological Macromolecules
Volume 249, Issue -, Pages 126068
Publisher
Elsevier BV
Online
2023-07-29
DOI
10.1016/j.ijbiomac.2023.126068
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Note: Only part of the references are listed.- Immunogenic cell stress and death
- (2022) Guido Kroemer et al. NATURE IMMUNOLOGY
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- (2021) Ming-Hao Hu et al. JOURNAL OF MEDICINAL CHEMISTRY
- G-quadruplex binders as cytostatic modulators of innate immune genes in cancer cells
- (2021) Giulia Miglietta et al. NUCLEIC ACIDS RESEARCH
- Enzyme-instructed and mitochondria-targeting peptide self-assembly to efficiently induce immunogenic cell death
- (2021) Debin Zheng et al. Acta Pharmaceutica Sinica B
- PT-112 induces immunogenic cell death and synergizes with immune checkpoint blockers in mouse tumor models
- (2020) Takahiro Yamazaki et al. OncoImmunology
- Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress
- (2020) Juliette Humeau et al. EMBO Molecular Medicine
- A drug-like imidazole-benzothiazole conjugate inhibits malignant melanoma by stabilizing the c-MYC G-quadruplex
- (2020) Tian-Ying Wu et al. BIOORGANIC CHEMISTRY
- R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation
- (2020) Chun-Ying Lee et al. Nature Communications
- DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives
- (2020) Lukas Perkhofer et al. GUT
- An ER‐Targeting Iridium(III) Complex That Induces Immunogenic Cell Death in Non‐Small‐Cell Lung Cancer
- (2020) Lili Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Enhancing anti-tumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors
- (2019) K M Heinhuis et al. ANNALS OF ONCOLOGY
- Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G-Quadruplex and Downregulate MYC
- (2019) Kai-Bo Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Crizotinib-induced immunogenic cell death in non-small cell lung cancer
- (2019) Peng Liu et al. Nature Communications
- G-Quadruplex Binders Induce Immunogenic Cell Death Markers in Aggressive Breast Cancer Cells
- (2019) Sarah Di Somma et al. Cancers
- Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c-MYC Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex
- (2018) Ming-Hao Hu et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Multifaceted Role of Chromosomal Instability in Cancer and Its Microenvironment
- (2018) Samuel F. Bakhoum et al. CELL
- DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells
- (2018) Alessio De Magis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation
- (2017) Giulia Miglietta et al. JOURNAL OF MEDICINAL CHEMISTRY
- Combining DNA Vaccine and AIDA-1 in Attenuated Salmonella Activates Tumor-Specific CD4 + and CD8 + T-cell Responses
- (2017) Yu Mei et al. Cancer Immunology Research
- T-cell immunometabolism against cancer
- (2016) Shuai Jiang et al. CANCER LETTERS
- Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
- (2016) Christina Pfirschke et al. IMMUNITY
- Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole
- (2016) Ming-Hao Hu et al. NUCLEIC ACIDS RESEARCH
- Endoplasmic Reticulum Stress in Immunity
- (2015) Sarah E. Bettigole et al. Annual Review of Immunology
- Telomere G-Quadruplex as a Potential Target to Accelerate Telomere Shortening by Expanding the Incomplete End-Replication of Telomere DNA
- (2015) Zheng Tan et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Ligand-Induced Conformational Changes with Cation Ejection upon Binding to Human Telomeric DNA G-Quadruplexes
- (2015) Adrien Marchand et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Live to die another way: modes of programmed cell death and the signals emanating from dying cells
- (2015) Yaron Fuchs et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA double strand break responses and chromatin alterations within the aging cell
- (2014) Karolin Klement et al. EXPERIMENTAL CELL RESEARCH
- Consensus guidelines for the detection of immunogenic cell death
- (2014) Oliver Kepp et al. OncoImmunology
- Higher Frequencies of GARP+CTLA-4+Foxp3+ T Regulatory Cells and Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Are Associated with Impaired T-Cell Functionality
- (2013) S. Kalathil et al. CANCER RESEARCH
- Quantitative visualization of DNA G-quadruplex structures in human cells
- (2013) Giulia Biffi et al. Nature Chemistry
- Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response
- (2011) J. Fucikova et al. CANCER RESEARCH
- DAMPs and PDT-mediated photo-oxidative stress: exploring the unknown
- (2011) Abhishek D. Garg et al. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
- Calreticulin exposure on malignant blasts predicts a cellular anticancer immune response in patients with acute myeloid leukemia
- (2010) M Wemeau et al. Cell Death & Disease
- Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway
- (2009) Angela Rizzo et al. NUCLEIC ACIDS RESEARCH
- Immunogenic death of colon cancer cells treated with oxaliplatin
- (2009) A Tesniere et al. ONCOGENE
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