Hypoxia and CD44 receptors dual-targeted nano-micelles with AGT-inhibitory activity for the targeting delivery of carmustine

Triggered azobenzene-based prodrugs and drug delivery systems

(2022) Jundong Zhu et al.   JOURNAL OF CONTROLLED RELEASE

Novel Lysosome-Targeting Fluorescence Off-On Photosensitizer for Near-Infrared Hypoxia Imaging and Photodynamic Therapy In Vitro and In Vivo

(2022) Shangli Ding et al.   MOLECULES

Development and biological evaluation of AzoBGNU: A novel hypoxia-activated DNA crosslinking prodrug with AGT-inhibitory activity

(2021) Qi Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Using solvent-free approach for preparing innovative biopolymer nanocomposites based on PGS/gelatin

(2020) Mohammad Hossein Aghajan et al.   EUROPEAN POLYMER JOURNAL

Design and characterization of poly(glycerol-sebacate)-co-poly(caprolactone) (PGS-co-PCL) and its nanocomposites as novel biomaterials: The promising candidate for soft tissue engineering

(2020) Mostafa Rostamian et al.   EUROPEAN POLYMER JOURNAL

Three-Dimensional Spheroids as In Vitro Preclinical Models for Cancer Research

(2020) Bárbara Pinto et al.   Pharmaceutics

Electrospun electroactive nanofibers of gelatin-oligoaniline/Poly (vinyl alcohol) templates for architecting of cardiac tissue with on-demand drug release

(2019) Shahrokh Shojaie et al.   POLYMERS FOR ADVANCED TECHNOLOGIES

Challenge between sequence presences of conductive additives on flexibility, dielectric and supercapacitance behaviors of nanofibrillated template of bacterial cellulose aerogels

(2019) Hadi Hosseini et al.   EUROPEAN POLYMER JOURNAL

The specific role of O6-methylguanine-DNA methyltransferase inhibitors in cancer chemotherapy

(2018) Guohui Sun et al.   Future Medicinal Chemistry

Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems

(2018) M. Danaei et al.   Pharmaceutics

Azo-based small molecular hypoxia responsive theranostic for tumor-specific imaging and therapy

(2018) Ying Zhou et al.   JOURNAL OF CONTROLLED RELEASE

Modeling and closed-loop control of particle size and initial burst of PLGA biodegradable nanoparticles for targeted drug delivery

(2017) Bahareh Baghaei et al.   JOURNAL OF APPLIED POLYMER SCIENCE

A new prospect in magnetic nanoparticle-based cancer therapy: Taking credit from mathematical tissue-mimicking phantom brain models

(2017) Mostafa Saeedi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Synthesis and Antitumor Activity Evaluation of a Novel Combi-nitrosourea Prodrug: BGCNU

(2017) Yameng Wang et al.   ACS Medicinal Chemistry Letters

T7 Peptide-Functionalized PEG-PLGA Micelles Loaded with Carmustine for Targeting Therapy of Glioma

(2016) Yunke Bi et al.   ACS Applied Materials & Interfaces

Hypoxia Responsive, Tumor Penetrating Lipid Nanoparticles for Delivery of Chemotherapeutics to Pancreatic Cancer Cell Spheroids

(2016) Prajakta Kulkarni et al.   BIOCONJUGATE CHEMISTRY

Mitochondria and nuclei dual-targeted heterogeneous hydroxyapatite nanoparticles for enhancing therapeutic efficacy of doxorubicin

(2016) Hui Xiong et al.   BIOMATERIALS

Synthesis and antitumor activity evaluation of a novel combi-nitrosourea prodrug: Designed to release a DNA cross-linking agent and an inhibitor of O6-alkylguanine-DNA alkyltransferase

(2016) Guohui Sun et al.   BIOORGANIC & MEDICINAL CHEMISTRY

3D tumor spheroids: an overview on the tools and techniques used for their analysis

(2016) Elisabete C. Costa et al.   BIOTECHNOLOGY ADVANCES

Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients

(2016) Christine Jungk et al.   BMC CANCER

Measurement of O 6 -alkylguanine-DNA alkyltransferase activity in tumour cells using stable isotope dilution HPLC-ESI⿿MS/MS

(2016) Guohui Sun et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Coordination-Induced Assembly of Intelligent Polysaccharide-Based Phototherapeutic Nanoparticles for Cancer Treatment

(2016) Ye Tian et al.   Advanced Healthcare Materials

Co-delivery of paclitaxel and gemcitabine via CD44-targeting nanocarriers as a prodrug with synergistic antitumor activity against human biliary cancer

(2015) Ilkoo Noh et al.   BIOMATERIALS

Planarians: an In Vivo Model for Regenerative Medicine

(2015) Ali Karami et al.   International Journal of Stem Cells

Highly Discriminating Photorelease of Anticancer Drugs Based on Hypoxia Activatable Phototrigger Conjugated Chitosan Nanoparticles

(2013) Qiuning Lin et al.   ADVANCED MATERIALS

Porous chitosan-hyaluronic acid scaffolds as a mimic of glioblastoma microenvironment ECM

(2013) Stephen J. Florczyk et al.   BIOMATERIALS

Advances in the development of hybrid anticancer drugs

(2013) Sébastien Fortin et al.   Expert Opinion on Drug Discovery

Hypoxia-Selective O6-Alkylguanine-DNA Alkyltransferase Inhibitors: Design, Synthesis, and Evaluation of 6-(Benzyloxy)-2-(aryldiazenyl)-9H-purines as Prodrugs of O6-Benzylguanine

(2013) Rui Zhu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of a cancer stem cell-like side population in the HeLa human cervical carcinoma cell line

(2013) KEFANG WANG et al.   Oncology Letters

Chloroethylnitrosourea-induced cell death and genotoxicity: Cell cycle dependence and the role of DNA double-strand breaks, HR and NHEJ

(2012) Teodora Nikolova et al.   CELL CYCLE

Multifaceted Roles of Alkyltransferase and Related Proteins in DNA Repair, DNA Damage, Resistance to Chemotherapy, and Research Tools

(2011) Anthony E. Pegg   CHEMICAL RESEARCH IN TOXICOLOGY

Silencing of CD44 by siRNA suppressed invasion, migration and adhesion to matrix, but not secretion of MMPs, of cholangiocarcinoma cells

(2011) Pongsanat Pongcharoen et al.   CLINICAL & EXPERIMENTAL METASTASIS

A phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain Tumor Consortium study

(2011) Katherine E. Warren et al.   JOURNAL OF NEURO-ONCOLOGY

Nanostructured hyaluronic acid-based materials for active delivery to cancer

(2010) Dmitri A Ossipov   Expert Opinion on Drug Delivery

Blood-Brain Barrier Disruption with Focused Ultrasound Enhances Delivery of Chemotherapeutic Drugs for Glioblastoma Treatment

(2010) Hao-Li Liu et al.   RADIOLOGY

DNA alkylation products formed by 1-(2-chloroethyl)-1-nitrosourea as molecular dosimeters of therapeutic response

(2008) William J. Bodell   JOURNAL OF NEURO-ONCOLOGY