Synthesis and antitumor activity evaluation of a novel combi-nitrosourea prodrug: Designed to release a DNA cross-linking agent and an inhibitor of O6-alkylguanine-DNA alkyltransferase

Published 2016 View Full Article

Authors

Keywords

Combi-nitrosourea, O, -alkylguanine-DNA alkyltransferase, dG–dC cross-links, Drug resistance, Cytotoxicity

Journal

BIOORGANIC & MEDICINAL CHEMISTRY

Volume 24, Issue 9, Pages 2097-2107

Publisher

Elsevier BV

Online

2016-03-26

DOI

10.1016/j.bmc.2016.03.041

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