Drug repositioning for ATTR amyloidosis by interactome network corrected by Graph Neural Networks and transcriptome analysis

A reference map of the human binary protein interactome

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Tafamidis: A Review in Transthyretin Amyloidosis with Polyneuropathy

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(2019) Mónica Inês et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Inhibition of the Amyloidogenesis of Transthyretin by Natural Products and Synthetic Compounds

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Drug repurposing: progress, challenges and recommendations

(2018) Sudeep Pushpakom et al.   NATURE REVIEWS DRUG DISCOVERY

Differential expression of Cathepsin E in transthyretin amyloidosis: from neuropathology to the immune system

(2017) Nádia Pereira Gonçalves et al.   Journal of Neuroinflammation

Resveratrol Administration Increases Transthyretin Protein Levels, Ameliorating AD Features: The Importance of Transthyretin Tetrameric Stability

(2016) Luís Miguel Santos et al.   MOLECULAR MEDICINE

Can you teach old drugs new tricks?

(2016) Nicola Nosengo   NATURE

DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants

(2016) Janet Piñero et al.   NUCLEIC ACIDS RESEARCH

Network-based in silico drug efficacy screening

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A survey of current trends in computational drug repositioning

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DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes

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A Proteome-Scale Map of the Human Interactome Network

(2014) Thomas Rolland et al.   CELL

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(2014) Y. Sekijima   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

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Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis

(2013) Teresa Coelho et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oxidative Stress and the Pathogenesis of Alzheimer's Disease

(2013) Yan Zhao et al.   Oxidative Medicine and Cellular Longevity

Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade

(2012) C. E. Bulawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PINA v2.0: mining interactome modules

(2011) Mark J. Cowley et al.   NUCLEIC ACIDS RESEARCH

Suppression of choroid plexus transthyretin levels by antisense oligonucleotide treatment

(2010) Merrill D. Benson et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS