Potentials of Endothelial Colony-Forming Cells: Applications in Hemostasis and Thrombosis Disorders, from Unveiling Disease Pathophysiology to Cell Therapy

Von Willebrand factor propeptide and pathophysiological mechanisms in European and Iranian patients with type 3 von Willebrand disease enrolled in the 3WINTERS‐IPS study

(2022) Maria Teresa Pagliari et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Post-COVID-19 patients show an increased endothelial progenitor cell production

(2022) Paula Poyatos et al.   Translational Research

Prevalence of Acute Pulmonary Embolism at Autopsy in Patients With COVID-19

(2022) Marco Zuin et al.   AMERICAN JOURNAL OF CARDIOLOGY

A Homozygous Deep Intronic Variant Causes Von Willebrand Factor Deficiency and Lack of Endothelial-Specific Secretory Organelles, Weibel–Palade Bodies

(2022) Hamideh Yadegari et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

VWF‐Gly2752Ser, a novel non‐cysteine substitution variant in the CK domain, exhibits severe secretory impairment by hampering C‐terminal dimer formation

(2022) Shuichi Okamoto et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

von Willebrand factor propeptide variants lead to impaired storage and ER retention in patient‐derived endothelial colony‐forming cells

(2022) Mackenzie Bowman et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A transcriptome analysis of basal and stimulated VWF release from endothelial cells derived from type 1 VWD patients

(2022) Robbie Kloosterman et al.   Blood Advances

Ex Vivo Modeling of the PC (Protein C) Pathway Using Endothelial Cells and Plasma: A Personalized Approach

(2022) Nadine Schwarz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Investigating Optimal Autologous Cellular Platforms for Prenatal or Perinatal Factor VIII Delivery to Treat Hemophilia A

(2021) Christopher Stem et al.   Frontiers in Cell and Developmental Biology

Morphological and functional alterations in endothelial colony-forming cells from recovered COVID-19 patients

(2021) José Antonio Alvarado-Moreno et al.   THROMBOSIS RESEARCH

Multifaceted pathomolecular mechanism of a VWF large deletion involved in the pathogenesis of severe VWD

(2021) Hamideh Yadegari et al.   Blood Advances

Angiogenesis‐Related Genes in Endothelial Progenitor Cells May Be Involved in Sickle Cell Stroke

(2020) Mirta T. Ito et al.   Journal of the American Heart Association

Human Peripheral Blood-Derived Endothelial Colony-Forming Cells Are Highly Similar to Mature Vascular Endothelial Cells yet Demonstrate a Transitional Transcriptomic Signature

(2020) Anton G. Kutikhin et al.   Cells

Endothelial characteristics in healthy endothelial colony forming cells; generating a robust and valid ex vivo model for vascular disease

(2020) Suzan de Boer et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Venous thromboembolism in critically ill COVID-19 patients receiving prophylactic or therapeutic anticoagulation: a systematic review and meta-analysis

(2020) Syed Shahzad Hasan et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

COVID-19 and Venous Thromboembolism: A Meta-analysis of Literature Studies

(2020) Alessandro Di Minno et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Ex vivo Improvement of a von Willebrand Disease Type 2A Phenotype Using an Allele-Specific Small-Interfering RNA

(2020) Annika de Jong et al.   THROMBOSIS AND HAEMOSTASIS

Interleukin-8 release by endothelial colony-forming cells isolated from idiopathic pulmonary fibrosis patients might contribute to their pathogenicity

(2019) Adeline Blandinières et al.   ANGIOGENESIS

Potential long-term treatment of hemophilia A by neonatal co-transplantation of cord blood-derived endothelial colony-forming cells and placental mesenchymal stromal cells

(2019) Kewa Gao et al.   Stem Cell Research & Therapy

Standardization of methods to quantify and culture endothelial colony‐forming cells derived from peripheral blood

(2019) David M. Smadja et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Endothelial Progenitor Cells Do Not Originate From the Bone Marrow

(2019) Takeshi Fujisawa et al.   CIRCULATION

Patients with aortic stenosis have von Willebrand factor abnormalities and increased proliferation of endothelial colony forming cells

(2019) Soundarya N. Selvam et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The role of fibrinolysis inhibition in engineered vascular networks derived from endothelial cells and adipose-derived stem cells

(2018) Severin Mühleder et al.   Stem Cell Research & Therapy

Prevention of in-stent restenosis with endothelial progenitor cell (EPC) capture stent placement combined with regional EPC transplantation: An atherosclerotic rabbit model

(2018) You-Hua Huang et al.   Cardiology Journal

Exocytosis of Weibel–Palade bodies: how to unpack a vascular emergency kit

(2018) M. Schillemans et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Predictors of stent thrombosis and their implications for clinical practice

(2018) Tommaso Gori et al.   Nature Reviews Cardiology

Blood endothelial cells: utility from ambiguity

(2017) Robert P. Hebbel   JOURNAL OF CLINICAL INVESTIGATION

Discrepant platelet and plasma von Willebrand factor in von Willebrand disease patients with p.Pro2808Leufs*24

(2017) M. L. Bowman et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Initial clonogenic potential of human endothelial progenitor cells is predictive of their further properties and establishes a functional hierarchy related to immaturity

(2017) Ségolène Ferratge et al.   Stem Cell Research

Endothelial Microparticles are Associated to Pathogenesis of Idiopathic Pulmonary Fibrosis

(2017) Nour C. Bacha et al.   Stem Cell Reviews and Reports

Endothelial Progenitors: A Consensus Statement on Nomenclature

(2017) Reinhold J. Medina et al.   Stem Cells Translational Medicine

Endothelial Microparticles are Associated to Pathogenesis of Idiopathic Pulmonary Fibrosis

(2017) Nour C. Bacha et al.   Stem Cell Reviews and Reports

Endothelial progenitor dysfunction associates with a type I interferon signature in primary antiphospholipid syndrome

(2016) Robert C Grenn et al.   ANNALS OF THE RHEUMATIC DISEASES

Characterization of aberrant splicing of von Willebrand factor in von Willebrand disease: an underrecognized mechanism

(2016) L. Hawke et al.   BLOOD

Intron retention resulting from a silent mutation in the VWF gene that structurally influences the 5' splice site

(2016) H. Yadegari et al.   BLOOD

Von Willebrand’s Disease

(2016) Frank W.G. Leebeek et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endothelial colony-forming cells: Biological and functional abnormalities in patients with recurrent, unprovoked venous thromboembolic disease

(2016) Jose Antonio Alvarado-Moreno et al.   THROMBOSIS RESEARCH

Therapeutic Potential of Human-Derived Endothelial Colony-Forming Cells in Animal Models

(2016) Dimitar Tasev et al.   TISSUE ENGINEERING PART B-REVIEWS

Angiogenic characteristics of blood outgrowth endothelial cells from patients with von Willebrand disease

(2015) D. J. Groeneveld et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Microfluidic Capture of Endothelial Colony-Forming Cells from Human Adult Peripheral Blood: Phenotypic and Functional ValidationIn Vivo

(2015) Ruei-Zeng Lin et al.   TISSUE ENGINEERING PART C-METHODS

Brief Report: Endothelial Progenitor Cell Phenotype and Function Are Impaired in Childhood-Onset Systemic Lupus Erythematosus

(2015) Smriti Mohan et al.   Arthritis & Rheumatology

Segregation of late outgrowth endothelial cells into functional endothelial CD34− and progenitor-like CD34+ cell populations

(2014) Cristina Ferreras et al.   ANGIOGENESIS

Omental implantation of BOECs in hemophilia dogs results in circulating FVIII antigen and a complex immune response

(2014) M. C. Ozelo et al.   BLOOD

Changes of Number and Function of Late Endothelial Progenitor Cells in Peripheral Blood of COPD Patients Combined with Pulmonary Hypertension

(2014) Pei Liu et al.   THORACIC AND CARDIOVASCULAR SURGEON

Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease

(2013) J.-W. Wang et al.   BLOOD

Increased adhesive and inflammatory properties in blood outgrowth endothelial cells from sickle cell anemia patients

(2013) Tatiana Mary Sakamoto et al.   MICROVASCULAR RESEARCH

Cellular and molecular basis of Von Willebrand disease: Studies on blood outgrowth endothelial cells

(2012) R.D. Starke et al.   ATHEROSCLEROSIS

Adipose-derived stem cells induce vascular tube formation of outgrowth endothelial cells in a fibrin matrix

(2012) Wolfgang Holnthoner et al.   Journal of Tissue Engineering and Regenerative Medicine

Establishment of outgrowth endothelial cells from peripheral blood

(2012) Javier Martin-Ramirez et al.   Nature Protocols

Late Outgrowth Endothelial Cells Resemble Mature Endothelial Cells and Are Not Derived from Bone Marrow

(2012) Olga Tura et al.   STEM CELLS

Stent Coated With Antibody Against Vascular Endothelial-Cadherin Captures Endothelial Progenitor Cells, Accelerates Re-Endothelialization, and Reduces Neointimal Formation

(2011) Woo-Hyun Lim et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular Incorporation of Endothelial Colony-Forming Cells Is Essential for Functional Recovery of Murine Ischemic Tissue Following Cell Therapy

(2011) Theresa M. Schwarz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial progenitor cell-dependent angiogenesis requires localization of the full-length form of uPAR in caveolae

(2011) F. Margheri et al.   BLOOD

Inflammasome Activation of IL-18 Results in Endothelial Progenitor Cell Dysfunction in Systemic Lupus Erythematosus

(2011) J. M. Kahlenberg et al.   JOURNAL OF IMMUNOLOGY

von Willebrand factor: the complex molecular genetics of a multidomain and multifunctional protein

(2011) R. SCHNEPPENHEIM et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Human endothelial progenitor cells isolated from COPD patients are dysfunctional

(2011) Xiaoran Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Endothelial von Willebrand factor regulates angiogenesis

(2010) R. D. Starke et al.   BLOOD

Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities

(2010) Reinhold J Medina et al.   BMC Medical Genomics

Blood outgrowth endothelial cell-based systemic delivery of antiangiogenic gene therapy for solid tumors

(2010) V Bodempudi et al.   CANCER GENE THERAPY

The Detrimental Effects of IFN-  on Vasculogenesis in Lupus Are Mediated by Repression of IL-1 Pathways: Potential Role in Atherogenesis and Renal Vascular Rarefaction

(2010) S. G. Thacker et al.   JOURNAL OF IMMUNOLOGY

High Frequency of Endothelial Colony Forming Cells Marks a Non-Active Myeloproliferative Neoplasm with High Risk of Splanchnic Vein Thrombosis

(2010) Vittorio Rosti et al.   PLoS One

Transplanted Late Outgrowth Endothelial Progenitor Cells as Cell Therapy Product for Stroke

(2010) Chahrazad Moubarik et al.   Stem Cell Reviews and Reports

Premature vascular damage in systemic lupus erythematosus

(2009) Mariana J. Kaplan   AUTOIMMUNITY

Genous™ endothelial progenitor cell-capturing stent system: a novel stent technology

(2009) Margo Klomp et al.   Expert Review of Medical Devices

Hypercoagulability and thrombotic complications in hemolytic anemias

(2009) K. I. Ataga   HAEMATOLOGICA

An assessment of the pathogenic significance of the R924Q von Willebrand factor substitution

(2009) E. BERBER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Endothelial progenitor cell dysfunction in rheumatic disease

(2009) Peter E. Westerweel et al.   Nature Reviews Rheumatology

Contribution of outgrowth endothelial cells from human peripheral blood on in vivo vascularization of bone tissue engineered constructs based on starch polycaprolactone scaffolds

(2008) Sabine Fuchs et al.   BIOMATERIALS

Thrombin bound to a fibrin clot confers angiogenic and haemostatic properties on endothelial progenitor cells

(2008) David M. Smadja et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Endothelial progenitor cells and colony-forming units in rheumatoid arthritis: association with clinical characteristics

(2008) C. G. Egan et al.   RHEUMATOLOGY

Patients with primary antiphospholipid antibody syndrome and without associated vascular risk factors present a normal endothelial function

(2008) P. Gresele et al.   THROMBOSIS RESEARCH

Use of endothelial progenitor cell capture stent (Genous Bio-Engineered R Stent) during primary percutaneous coronary intervention in acute myocardial infarction: Intermediate- to long-term clinical follow-up

(2007) Melissa Co et al.   AMERICAN HEART JOURNAL

Genetic endothelial systems biology of sickle stroke risk

(2007) L. Chang Milbauer et al.   BLOOD