Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy

HIF-1α Alleviates High-Glucose-Induced Renal Tubular Cell Injury by Promoting Parkin/PINK1-Mediated Mitophagy

(2022) Lu Yu et al.   Frontiers in Medicine

Defective mitophagy in aged macrophages promotes mitochondrial DNA cytosolic leakage to activate STING signaling during liver sterile inflammation

(2022) Weizhe Zhong et al.   AGING CELL

Mitochondria bridge HIF signaling and ferroptosis blockage in acute kidney injury

(2022) Wenju Li et al.   Cell Death & Disease

XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury

(2022) Zheng Liu et al.   Redox Biology

Oxidative Stress and Ischemia/Reperfusion Injury in Kidney Transplantation: Focus on Ferroptosis, Mitophagy and New Antioxidants

(2022) Simona Granata et al.   Antioxidants

Mitochondrial Ferritin Deficiency Promotes Osteoblastic Ferroptosis Via Mitophagy in Type 2 Diabetic Osteoporosis

(2021) XinDong Wang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Characterization of ferroptosis in kidney tubular cell death under diabetic conditions

(2021) Seonghun Kim et al.   Cell Death & Disease

MiR-142-3p ameliorates high glucose-induced renal tubular epithelial cell injury by targeting BOD1

(2021) Ningmin Zhao et al.   Clinical and Experimental Nephrology

STING1 Promotes Ferroptosis Through MFN1/2-Dependent Mitochondrial Fusion

(2021) Changfeng Li et al.   Frontiers in Cell and Developmental Biology

A novel identified circular RNA, mmu_mmu_circRNA_0000309 involves in Germacrone-mediated the improvement of diabetic nephropathy through regulating ferroptosis by targeting miR-188-3p/GPX4 signaling axis

(2021) Juan Jin et al.   ANTIOXIDANTS & REDOX SIGNALING

miR-188-3p abolishes germacrone-mediated podocyte protection in a mouse model of diabetic nephropathy in type I diabetes through triggering mitochondrial injury

(2021) Yunguang Wang et al.   Bioengineered

Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death

(2020) Changfeng Li et al.   Autophagy

PINK1/Parkin mediated mitophagy ameliorates palmitic acid-induced apoptosis through reducing mitochondrial ROS production in podocytes

(2020) Xu-shun Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Garciesculenxanthone B induces PINK1-Parkin-mediated mitophagy and prevents ischemia-reperfusion brain injury in mice

(2020) Man Wu et al.   ACTA PHARMACOLOGICA SINICA

Ferroptosis involves in renal tubular cell death in diabetic nephropathy

(2020) Yue Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Melatonin Suppresses Ferroptosis Induced by High Glucose via Activation of the Nrf2/HO-1 Signaling Pathway in Type 2 Diabetic Osteoporosis

(2020) Hongdong Ma et al.   Oxidative Medicine and Cellular Longevity

PGRN acts as a novel regulator of mitochondrial homeostasis by facilitating mitophagy and mitochondrial biogenesis to prevent podocyte injury in diabetic nephropathy

(2019) Di Zhou et al.   Cell Death & Disease

Mitochondrial dysfunction in diabetic kidney disease

(2019) Pascal Zhongping Wei et al.   CLINICA CHIMICA ACTA

WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2019) Pouya Saeedi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation

(2019) Qisheng Lin et al.   Redox Biology

Germacrone alleviates collagen-induced arthritis via regulating Th1/Th2 balance and NF-κB activation

(2019) Zongru Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury

(2019) Hiroshi Maekawa et al.   Cell Reports

NLRP3 deficiency ameliorates renal inflammation and fibrosis in diabetic mice

(2018) Ming Wu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Iron Homeostasis in Healthy Kidney and its Role in Acute Kidney Injury

(2018) Yogesh Scindia et al.   SEMINARS IN NEPHROLOGY

Research Progress on Mechanism of Podocyte Depletion in Diabetic Nephropathy

(2017) Haoran Dai et al.   Journal of Diabetes Research

The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1

(2017) Li Xiao et al.   Redox Biology

Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

(2016) Diego Martin-Sanchez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

End-stage renal disease and survival in people with diabetes: a national database linkage study

(2014) S. Bell et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Diabetic nephropathy: diagnosis and treatment

(2013) Daniel Fineberg et al.   Nature Reviews Endocrinology

Anti-tumor potential of ethanol extract of Curcuma phaeocaulis Valeton against breast cancer cells

(2011) Xiuping Chen et al.   PHYTOMEDICINE

The role of tubular injury in diabetic nephropathy

(2009) Caroline Jane Magri et al.   European Journal of Internal Medicine