‘Speed‐ageing’ of human skin in serum‐free organ culture ex vivo: An instructive novel assay for preclinical human skin ageing research demonstrates senolytic effects of caffeine and 2,5‐dimethylpyrazine

Biomarkers of Tretinoin Precursors and Tretinoin Efficacy in Patients With Moderate to Severe Facial Photodamage

(2022) Anna L. Chien et al.   JAMA Dermatology

Human organ rejuvenation by VEGF-A: Lessons from the skin

(2022) Aviad Keren et al.   Science Advances

Aging in the sebaceous gland

(2022) Xiaoxiao Hou et al.   Frontiers in Cell and Developmental Biology

Senescence and cancer — role and therapeutic opportunities

(2022) Clemens A. Schmitt et al.   Nature Reviews Clinical Oncology

Skin ageing: Clinical aspects and in vivo microscopic patterns observed with reflectance confocal microscopy and optical coherence tomography

(2022) Claudia Pezzini et al.   EXPERIMENTAL DERMATOLOGY

Inflammaging and the Skin

(2021) Suzanne M. Pilkington et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TGFβ Signaling in Photoaging and UV-Induced Skin Cancer

(2021) Yao Ke et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Environmentally-Induced (Extrinsic) Skin Aging: Exposomal Factors and Underlying Mechanisms

(2021) Jean Krutmann et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Connective Tissue and Fibroblast Senescence in Skin Aging

(2021) Meinhard Wlaschek et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hair Follicle Chemosensation: TRPM5 Signaling Is Required for Anagen Maintenance

(2021) Andrei Mardaryev et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Sirtuin 1 and Skin: Implications in Intrinsic and Extrinsic Aging—A Systematic Review

(2021) Angelika Bielach-Bazyluk et al.   Cells

PPARγ signaling protects hair follicle stem cells from chemotherapy‐induced apoptosis and epithelial‐mesenchymal transition

(2021) I. Piccini et al.   BRITISH JOURNAL OF DERMATOLOGY

The regional distribution of melanosomes in the epidermis affords a localized intensive photoprotection for basal keratinocyte stem cells

(2021) Shan Jiang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Sensory Reinnervation of Human Skin by Human Neural Stem Cell‒Derived Peripheral Neurons Ex Vivo

(2021) Jérémy Chéret et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A role for estrogen in skin ageing and dermal biomechanics

(2021) Holly N. Wilkinson et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Long-Term Caffeine Intake Exerts Protective Effects on Intestinal Aging by Regulating Vitellogenesis and Mitochondrial Function in an Aged Caenorhabditis Elegans Model

(2021) Hyemin Min et al.   Nutrients

Higher Coffee Consumption Is Associated With Slower Cognitive Decline and Less Cerebral Aβ-Amyloid Accumulation Over 126 Months: Data From the Australian Imaging, Biomarkers, and Lifestyle Study

(2021) Samantha L. Gardener et al.   Frontiers in Aging Neuroscience

A 2A adenosine receptor antagonists: From caffeine to selective non‐xanthines

(2020) Kenneth A. Jacobson et al.   BRITISH JOURNAL OF PHARMACOLOGY

Getting under the skin of hair aging: the impact of the hair follicle environment

(2020) Rachael Williams et al.   EXPERIMENTAL DERMATOLOGY

The quest to slow ageing through drug discovery

(2020) Linda Partridge et al.   NATURE REVIEWS DRUG DISCOVERY

The biology of human hair greying

(2020) James D. B. O'Sullivan et al.   BIOLOGICAL REVIEWS

SASP‐induced macrophage dysfunction may contribute to accelerated senescent fibroblast accumulation in the dermis

(2020) Yuichiro Ogata et al.   EXPERIMENTAL DERMATOLOGY

Cellular Senescence and the Senescence-Associated Secretory Phenotype as Drivers of Skin Photoaging

(2020) Eleni Fitsiou et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Clock Regulation of Skin Regeneration in Stem Cell Aging

(2020) Patrick-Simon Welz   JOURNAL OF INVESTIGATIVE DERMATOLOGY

UV radiation on scalp skin surface induces scalp hair follicle damage ex vivo and is alleviated by the topical treatment with caffeine

(2019) Jennifer Gherardini et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE

Thyroxine (T4) may promote re-epithelialisation and angiogenesis in wounded human skin ex vivo

(2019) Guo-You Zhang et al.   PLoS One

Molecular Mechanisms of Dermal Aging and Antiaging Approaches

(2019) Jung-Won Shin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia

(2019) Talveen S Purba et al.   EMBO Molecular Medicine

Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction

(2019) Stella Victorelli et al.   EMBO JOURNAL

Melatonin: A Cutaneous Perspective on its Production, Metabolism, and Functions

(2018) Andrzej T. Slominski et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The renaissance of human skin organ culture: A critical reappraisal

(2018) Lijuan Zhou et al.   DIFFERENTIATION

What is the role of mitochondrial dysfunction in skin photoaging?

(2017) Khimara Naidoo et al.   EXPERIMENTAL DERMATOLOGY

Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin

(2017) Michael Kemp et al.   MOLECULES

Type XVII collagen coordinates proliferation in the interfollicular epidermis

(2017) Mika Watanabe et al.   eLife

Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses

(2016) Servet Özcan et al.   Aging-US

Markers of cellular senescence. Telomere shortening as a marker of cellular senescence

(2016) Alexandra Bernadotte et al.   Aging-US

Thyroid Hormones Enhance Mitochondrial Function in Human Epidermis

(2016) Silvia Vidali et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The impact of intrinsic ageing on the protein composition of the dermal-epidermal junction

(2016) Abigail K. Langton et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis

(2016) H. Matsumura et al.   SCIENCE

Novel approaches to characterize age-related remodelling of the dermal-epidermal junction in 2D, 3D andin vivo

(2016) V. L. Newton et al.   SKIN RESEARCH AND TECHNOLOGY

Mitochondrial Function in Murine Skin Epithelium Is Crucial for Hair Follicle Morphogenesis and Epithelial–Mesenchymal Interactions

(2015) Jennifer E. Kloepper et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Temporally distinct roles of ATM and ROS in genotoxic-stress-dependent induction and maintenance of cellular senescence

(2014) R. R. Nair et al.   JOURNAL OF CELL SCIENCE

Quantitative analysis of intrinsic skin aging in dermal papillae by in vivo harmonic generation microscopy

(2014) Yi-Hua Liao et al.   Biomedical Optics Express

Thyrotropin-Releasing Hormone (TRH) Promotes Wound Re-Epithelialisation in Frog and Human Skin

(2013) Natalia T. Meier et al.   PLoS One

Development of a short-term human full-thickness skin organ culture model in vitro under serum-free conditions

(2012) Konrad Kleszczyński et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number

(2012) Christopher T. Campbell et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Changes in glycosaminoglycans and related proteoglycans in intrinsically aged human skin in vivo

(2011) Jang-Hee Oh et al.   EXPERIMENTAL DERMATOLOGY

Triphenylphosphine Oxide Is a Potent and Selective Inhibitor of the Transient Receptor Potential Melastatin-5 Ion Channel

(2010) R. Kyle Palmer et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Thyroid-Stimulating Hormone, a Novel, Locally Produced Modulator of Human Epidermal Functions, Is Regulated by Thyrotropin-Releasing Hormone and Thyroid Hormones

(2010) Enikő Bodó et al.   ENDOCRINOLOGY