Inhibiting autophagy to boost antitumor immunity with tetramethylpyrazine-loaded and PD-L1-targeting liposomal nanoparticles

Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles

(2022) Ya-jing Li et al.   ACTA PHARMACOLOGICA SINICA

Turning cold tumors hot: from molecular mechanisms to clinical applications

(2022) Jiahui Zhang et al.   TRENDS IN IMMUNOLOGY

Intratumoral Therapy to Make a “Cold” Tumor “Hot”: The Jury Is Still Out

(2022) Salman R. Punekar et al.   CLINICAL CANCER RESEARCH

Cancer-associated fibroblasts in non-small cell lung cancer: Recent advances and future perspectives

(2021) Hongfang Zhang et al.   CANCER LETTERS

Chloroquine and hydroxychloroquine in antitumor therapies based on autophagy-related mechanisms

(2021) Paulo Michel Pinheiro Ferreira et al.   PHARMACOLOGICAL RESEARCH

Exercise and the immune system: taking steps to improve responses to cancer immunotherapy

(2021) Michael P Gustafson et al.   Journal for ImmunoTherapy of Cancer

Tetramethylpyrazine alleviates diabetes-induced high platelet response and endothelial adhesion via inhibiting NLRP3 inflammasome activation

(2021) Haowen Zhang et al.   PHYTOMEDICINE

Icaritin Exacerbates Mitophagy and Synergizes with Doxorubicin to Induce Immunogenic Cell Death in Hepatocellular Carcinoma

(2020) Zhuo Yu et al.   ACS Nano

Tetramethylpyrazine ameliorates hepatic fibrosis through autophagy-mediated inflammation

(2020) Zhigao Hu et al.   Biochemistry and Cell Biology

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

(2020) Keisuke Yamamoto et al.   NATURE

Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti–PD-1/PD-L1 immunotherapy

(2020) Muhammad Zaeem Noman et al.   Science Advances

Comparison of the therapeutic effects of lobaplatin and carboplatin on retinoblastoma in vitro and in vivo

(2020) Zijun Zhou et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34

(2020) Bassam Janji et al.   Autophagy

Nano-Enhanced Cancer Immunotherapy: Immunology Encounters Nanotechnology

(2020) Ernesto Bockamp et al.   Cells

Molecular Insights into the Multifunctional Role of Natural Compounds: Autophagy Modulation and Cancer Prevention

(2020) Md. Ataur Rahman et al.   Biomedicines

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

(2019) Jérôme Galon et al.   NATURE REVIEWS DRUG DISCOVERY

Delivery technologies for cancer immunotherapy

(2019) Rachel S. Riley et al.   NATURE REVIEWS DRUG DISCOVERY

Liposome and immune system interplay: Challenges and potentials

(2019) Fahimeh Zahednezhad et al.   JOURNAL OF CONTROLLED RELEASE

Targeting autophagy in cancer

(2018) Angelique V. Onorati et al.   CANCER

Molecular targeted therapy: treating cancer with specificity

(2018) Yeuan Ting Lee et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner

(2017) Takouhie Mgrditchian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells

(2017) Thaiz Rivera Vargas et al.   Nature Communications

Inhibition of autophagy enhances the anticancer activity of silver nanoparticles

(2014) Jun Lin et al.   Autophagy

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS