Tetramethylpyrazine alleviates diabetes-induced high platelet response and endothelial adhesion via inhibiting NLRP3 inflammasome activation

Antithrombotic therapy in diabetes: which, when, and for how long?

(2021) Ramzi A Ajjan et al.   EUROPEAN HEART JOURNAL

Salvianolic Acid A Ameliorates Early-Stage Atherosclerosis Development by Inhibiting NLRP3 Inflammasome Activation in Zucker Diabetic Fatty Rats

(2020) Quanxin Ma et al.   MOLECULES

Understanding Inflammatory Responses in the Manifestation of Prothrombotic Phenotypes

(2020) Shankar Chanchal et al.   Frontiers in Cell and Developmental Biology

High glucose mediates NLRP3 inflammasome activation via upregulation of ELF3 expression

(2020) Jing Wang et al.   Cell Death & Disease

Effects of a dammarane-type saponin, ginsenoside Rd, in nicotine-induced vascular endothelial injury

(2020) Baobao Zhang et al.   PHYTOMEDICINE

Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging

(2019) Hanzhi Luo et al.   Cell Reports

Tetramethylpyrazine ameliorates depression by inhibiting TLR4-NLRP3 inflammasome signal pathway in mice

(2019) Songnian Fu et al.   PSYCHOPHARMACOLOGY

NLRP3 inflammasome as a potential treatment in ischemic stroke concomitant with diabetes

(2019) Pu Hong et al.   Journal of Neuroinflammation

Downregulation of hsa_circ_0068087 ameliorates TLR4/NF-κB/NLRP3 inflammasome-mediated inflammation and endothelial cell dysfunction in high glucose conditioned by sponging miR-197

(2019) Jie Cheng et al.   GENE

NLRP3 inflammasome promotes diabetes-induced endothelial inflammation and atherosclerosis

(2019) Zhaofei Wan et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Tetramethylpyrazine alleviates diabetic nephropathy through the activation of Akt signalling pathway in rats

(2019) Uddipak Rai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effects and potential mechanism of salvianolic acid B on sodium laurate-induced thromboangiitis obliterans in rats

(2019) Ziru Zhang et al.   PHYTOMEDICINE

Modulatory Mechanisms of the NLRP3 Inflammasomes in Diabetes

(2019) Sujuan Ding et al.   Biomolecules

ERK5/KLF2 activation is involved in the reducing effects of puerarin on monocyte adhesion to endothelial cells and atherosclerotic lesion in apolipoprotein E-deficient mice

(2018) Yan Deng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

TLR4-dependent upregulation of the platelet NLRP3 inflammasome promotes platelet aggregation in a murine model of hindlimb ischemia

(2018) Sebastian Vogel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Salicylic acid retention impairs aspirin reactivity in type 2 diabetes

(2017) Haowen Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease

(2017) Mattia Cocco et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of an automated light transmission aggregometry

(2017) Li-qin Ling et al.   PLATELETS

Hemostasis, endothelial stress, inflammation, and the metabolic syndrome

(2017) Gerald Grandl et al.   Seminars in Immunopathology

Ligustrazine disrupts lipopolysaccharide-activated NLRP3 inflammasome pathway associated with inhibition of Toll-like receptor 4 in hepatocytes

(2016) Feng Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Exogenous Hydrogen Sulfide Attenuates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation by Suppressing TLR4/NF-κB Pathway in H9c2 Cells

(2016) Zena Huang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effect of traditional Uyghur medicine abnormal Savda Munziq extract on rabbit platelet aggregation in vitro and rat arteriovenous shunt thrombosis in vivo

(2015) Anwar Umar et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin

(2013) Latt S Mansor et al.   Cardiovascular Diabetology

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I

(2013) Francesco Paneni et al.   EUROPEAN HEART JOURNAL

Nlrp3 Inflammasome Activation in Type 2 Diabetes: Is It Clinically Relevant?

(2012) Vishwa Deep Dixit   DIABETES

The influence of aspirin dose and glycemic control on platelet inhibition in patients with type 2 diabetes mellitus

(2012) B. A. LEMKES et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Elevated procoagulant microparticles expressing endothelial and platelet markers in essential thrombocythemia

(2009) M. C. Trappenburg et al.   HAEMATOLOGICA

Tetramethylpyrazine suppresses interleukin-8 expression in LPS-stimulated human umbilical vein endothelial cell by blocking ERK, p38 and nulear factor-κB signaling pathways

(2009) Xiu-Ying Li et al.   JOURNAL OF ETHNOPHARMACOLOGY