Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity

A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis

(2022) Anne Loft et al.   Cell Metabolism

Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities

(2022) Nicola Cosgrove et al.   Nature Communications

The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer

(2021) Theresa E. Hickey et al.   NATURE MEDICINE

Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites

(2021) Marina Kulik et al.   NUCLEIC ACIDS RESEARCH

Ki67 and progesterone receptor status predicts sensitivity to palbociclib: a real-world study

(2021) Xiying Shao et al.   Annals of Translational Medicine

Duality of glucocorticoid action in cancer: tumor-suppressor or oncogene?

(2021) Isabel Mayayo-Peralta et al.   ENDOCRINE-RELATED CANCER

Glucocorticoid Signaling and Epigenetic Alterations in Stress-Related Disorders

(2021) Niki Mourtzi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Web-Based Survival Analysis Tool Tailored for Medical Research (KMplot): Development and Implementation

(2021) András Lánczky et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

A single-cell and spatially resolved atlas of human breast cancers

(2021) Sunny Z. Wu et al.   NATURE GENETICS

Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer

(2021) Stefan Prekovic et al.   Nature Communications

Estrogen Receptor on the move: Cistromic plasticity and its implications in breast cancer

(2020) Isabel Mayayo-Peralta et al.   MOLECULAR ASPECTS OF MEDICINE

Glucocorticoids promote breast cancer metastasis

(2019) Milan M. S. Obradović et al.   NATURE

Cyclin E1 Expression and Palbociclib Efficacy in Previously Treated Hormone Receptor–Positive Metastatic Breast Cancer

(2019) Nicholas C. Turner et al.   JOURNAL OF CLINICAL ONCOLOGY

Cistrome-GO: a web server for functional enrichment analysis of transcription factor ChIP-seq peaks

(2019) Shaojuan Li et al.   NUCLEIC ACIDS RESEARCH

ZBTB7A mediates the transcriptional repression activity of the androgen receptor in prostate cancer

(2019) Changmeng Cai et al.   CANCER RESEARCH

Assessment of Long-term Distant Recurrence-Free Survival Associated With Tamoxifen Therapy in Postmenopausal Patients With Luminal A or Luminal B Breast Cancer

(2019) Nancy Y. Yu et al.   JAMA Oncology

DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput

(2019) Vadim Demichev et al.   NATURE METHODS

Discovery of a Glucocorticoid Receptor (GR) Activity Signature Using Selective GR Antagonism in ER-Negative Breast Cancer

(2018) Diana C. West et al.   CLINICAL CANCER RESEARCH

Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer

(2018) Linda S Lindström et al.   JNCI-Journal of the National Cancer Institute

Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer

(2018) Tesa M. Severson et al.   Nature Communications

Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer

(2018) Linda S Lindström et al.   JNCI-Journal of the National Cancer Institute

Adjuvant dose-dense doxorubicin-cyclophosphamide versus docetaxel-doxorubicin-cyclophosphamide for high-risk breast cancer: First results of the randomised MATADOR trial (BOOG 2004-04)

(2018) A.G.J. van Rossum et al.   EUROPEAN JOURNAL OF CANCER

Glucocorticoid receptors: finding the middle ground

(2017) Sofie J. Desmet et al.   JOURNAL OF CLINICAL INVESTIGATION

Glucocorticoid Receptor:MegaTrans Switching Mediates the Repression of an ERα-Regulated Transcriptional Program

(2017) Feng Yang et al.   MOLECULAR CELL

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

(2017) Hongchao Pan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acute lymphoblastic leukemia: a comprehensive review and 2017 update

(2017) T Terwilliger et al.   Blood Cancer Journal

Use of Molecular Tools to Identify Patients With Indolent Breast Cancers With Ultralow Risk Over 2 Decades

(2017) Laura J. Esserman et al.   JAMA Oncology

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

(2016) George Sflomos et al.   CANCER CELL

Annual Hazard Rates of Recurrence for Breast Cancer During 24 Years of Follow-Up: Results From the International Breast Cancer Study Group Trials I to V

(2016) Marco Colleoni et al.   JOURNAL OF CLINICAL ONCOLOGY

The molecular basis of breast cancer pathological phenotypes

(2016) Yujing J Heng et al.   JOURNAL OF PATHOLOGY

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Multiple layers of transcriptional regulation by PLZF in NKT-cell development

(2016) Ai-Ping Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using combined evidence from replicates to evaluate ChIP-seq peaks

(2015) Vahid Jalili et al.   BIOINFORMATICS

Clinical implications of the intrinsic molecular subtypes of breast cancer

(2015) Aleix Prat et al.   BREAST

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Comprehensive Overview of the Structure and Regulation of the Glucocorticoid Receptor

(2014) Sofie Vandevyver et al.   ENDOCRINE REVIEWS

Frequent promoter hypermethylation and expression reduction of the glucocorticoid receptor gene in breast tumors

(2014) Kirsten A Nesset et al.   Epigenetics

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade

(2013) Vivek K. Arora et al.   CELL

Hypermethylation reduces expression of tumor-suppressor PLZF and regulates proliferation and apoptosis in non-small-cell lung cancers

(2013) Xiaotian Wang et al.   FASEB JOURNAL

Endogenous Purification Reveals GREB1 as a Key Estrogen Receptor Regulatory Factor

(2013) Hisham Mohammed et al.   Cell Reports

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

Activation of the Glucocorticoid Receptor Is Associated with Poor Prognosis in Estrogen Receptor-Negative Breast Cancer

(2011) D. Pan et al.   CANCER RESEARCH

Crosstalk between Glucocorticoid Receptor and Nutritional Sensor mTOR in Skeletal Muscle

(2011) Noriaki Shimizu et al.   Cell Metabolism

A public genome-scale lentiviral expression library of human ORFs

(2011) Xiaoping Yang et al.   NATURE METHODS

Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM

(2010) Charles J. Vaske et al.   BIOINFORMATICS

Role of Glucocorticoids in Breast Cancer

(2010) Jayant S. Vaidya et al.   CURRENT PHARMACEUTICAL DESIGN

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Estrogen Receptor, Progesterone Receptor, and Glucocorticoid Receptor Expression in Normal Breast Tissue, Breast In Situ Carcinoma, and Invasive Breast Cancer

(2010) Frederic Buxant et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY