Functionalized cyclopentenes through a tandem NHC-catalyzed dynamic kinetic resolution and ambient temperature decarboxylation: mechanistic insight and synthetic application

Catalytic kinetic resolution of a dynamic racemate: highly stereoselective β-lactone formation by N-heterocyclic carbene catalysis

(2014) Ryne C. Johnston et al.   Chemical Science

Enantioselective N-Heterocyclic Carbene Catalyzed Annulation Reactions with Imidazolidinones

(2013) Elizabeth O'Bryan McCusker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bis(amino)cyclopropenylidenes as Organocatalysts for Acyl Anion and Extended Umpolung Reactions

(2013) Myron M. D. Wilde et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic C–C Bond-Forming Multi-Component Cascade or Domino Reactions: Pushing the Boundaries of Complexity in Asymmetric Organocatalysis

(2013) Chandra M. R. Volla et al.   CHEMICAL REVIEWS

A Dual Lewis Base Activation Strategy for Enantioselective Carbene-Catalyzed Annulations

(2013) Javier Izquierdo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Homoenolate Additions to Acyl Phosphonates through Rational Design of a Tailored N-Heterocyclic Carbene Catalyst

(2013) Ki Po Jang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic C–H Bond Arylation of Aldehydes to Bis-heteroaryl Ketones

(2013) Qiao Yan Toh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC-Catalyzed Reaction of Enals with Hydroxy Chalcones: Diastereoselective Synthesis of Functionalized Coumarins

(2013) Anup Bhunia et al.   ORGANIC LETTERS

Construction of Successive Chiral Centers Adjacent to a Chiral Tetraalkylated Quaternary Center Using an Asymmetric Aldol Reaction

(2013) Tomoyuki Esumi et al.   ORGANIC LETTERS

Highly Chemo- and Enantioselective Cross-Benzoin Reaction of Aliphatic Aldehydes and α-Ketoesters

(2013) Karen Thai et al.   ORGANIC LETTERS

N-Heterocyclic Carbene Catalyzed Addition of Aldehydes to Diazo Compounds: Stereoselective Synthesis of N-Acylhydrazones

(2013) Fábio M. F. Santos et al.   ORGANIC LETTERS

Concise synthesis of prenylated and geranylated chalcone natural products by regiospecific iodination and Suzuki coupling reactions

(2013) Haomeng Wang et al.   TETRAHEDRON LETTERS

Mechanistic insights into the triazolylidene-catalysed Stetter and benzoin reactions: role of the N-aryl substituent

(2013) Christopher J. Collett et al.   Chemical Science

N-Heterocyclic Carbene-Catalyzed Enantioselective Intramolecular N-Tethered Aldehyde–Ketone Benzoin Reactions

(2013) Min-Qiang Jia et al.   ACS Catalysis

An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones

(2012) Julien Dugal-Tessier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Cross-Aza-Benzoin Reactions of Aliphatic Aldehydes withN-Boc-Protected Imines

(2012) Daniel A. DiRocco et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Dynamic Kinetic Resolutions with N-Heterocyclic Carbenes: Asymmetric Synthesis of Highly Substituted β-Lactones

(2012) Daniel T. Cohen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic-Carbene-Catalyzed Asymmetric Oxidative Hetero-Diels-Alder Reactions with Simple Aliphatic Aldehydes

(2012) Xiaodan Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

(2012) Javier Izquierdo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Controlled β-protonation and [4+2] cycloaddition of enals and chalconesvia N-heterocyclic carbene/acid catalysis: toward substrate independent reaction control

(2012) Zhenqian Fu et al.   CHEMICAL COMMUNICATIONS

Highly Enantioselective Intermolecular Stetter Reaction of Simple Acrylates: Synthesis of α-Chiral γ-Ketoesters

(2012) Nathalie E. Wurz et al.   CHEMISTRY-A EUROPEAN JOURNAL

Evolution of asymmetric organocatalysis: multi- and retrocatalysis

(2012) Raffael C. Wende et al.   GREEN CHEMISTRY

Diastereoselective and Enantioselective Desymmetrization of α-Substituted Cyclohexadienones via Intramolecular Stetter Reaction

(2012) Min-Qiang Jia et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanism and Stereoselectivity of a Dual Amino-Catalyzed Robinson Annulation: Rare Duumvirate Stereocontrol

(2012) Matthew D. Pierce et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Cascade Reaction Actuated by Nucleophilic Heterocyclic Carbene Catalyzed Intramolecular Addition of Enals via Homoenolate to α,β-Unsaturated Esters: Efficient Synthesis of Coumarin Derivatives

(2012) C. R. Sinu et al.   ORGANIC LETTERS

Access to Spirocyclic Oxindoles via N-Heterocyclic Carbene-Catalyzed Reactions of Enals and Oxindole-Derived α,β-Unsaturated Imines

(2012) Kun Jiang et al.   ORGANIC LETTERS

N-Heterocyclic Carbene (NHC)-Catalyzed Highly Diastereo- and Enantioselective Oxo-Diels–Alder Reactions for Synthesis of Fused Pyrano[2,3-b]indoles

(2012) Limin Yang et al.   ORGANIC LETTERS

Multicatalytic Asymmetric Synthesis of Complex Tetrahydrocarbazoles via a Diels–Alder/Benzoin Reaction Sequence

(2012) Yankai Liu et al.   ORGANIC LETTERS

Lewis Acid Activated Synthesis of Highly Substituted Cyclopentanes by the N-Heterocyclic Carbene Catalyzed Addition of Homoenolate Equivalents to Unsaturated Ketoesters

(2011) Daniel T. Cohen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions

(2011) Albert Moyano et al.   CHEMICAL REVIEWS

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Low-loading asymmetric organocatalysis

(2011) Francesco Giacalone et al.   CHEMICAL SOCIETY REVIEWS

A Family of Thiazolium Salt Derived N-Heterocyclic Carbenes (NHCs) for Organocatalysis: Synthesis, Investigation and Application in Cross-Benzoin Condensation

(2011) Isabel Piel et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthetic and Quantum Mechanical Studies into the N-Heterocyclic Carbene Catalyzed (4 + 2) Cycloaddition

(2011) Sarah J. Ryan et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene and Brønsted Acid Cooperative Catalysis: Asymmetric Synthesis oftrans-γ-Lactams

(2011) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC-Catalyzed/Titanium(IV)−Mediated Highly Diastereo- and Enantioselective Dimerization of Enals

(2011) Daniel T. Cohen et al.   ORGANIC LETTERS

Enantioselective Diels–Alder Reactions of Enals and Alkylidene Diketones Catalyzed by N-Heterocyclic Carbenes

(2011) Xinqiang Fang et al.   ORGANIC LETTERS

NHC-catalysed, chemoselective crossed-acyloin reactions

(2011) Christopher A. Rose et al.   Chemical Science

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to γ-lactams

(2010) Dustin E. A. Raup et al.   Nature Chemistry

Recent advances in carbon–carbon bond-forming reactions involving homoenolates generated by NHC catalysis

(2008) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Uniformly convergent n-tuple-ζ augmented polarized (nZaP) basis sets for complete basis set extrapolations. I. Self-consistent field energies

(2008) Shijun Zhong et al.   JOURNAL OF CHEMICAL PHYSICS

The advent and development of organocatalysis

(2008) David W. C. MacMillan   NATURE