Controlled β-protonation and [4+2] cycloaddition of enals and chalconesvia N-heterocyclic carbene/acid catalysis: toward substrate independent reaction control

Enantioselective Synthesis of β,γ-Unsaturated α-Fluoroesters Catalyzed by N-Heterocyclic Carbenes

(2012) Yu-Ming Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Intermolecular Stetter Reactions of Enolizable Aldehydes with Nitrostyrenes: Computational Study Provides Insight into the Success of the Catalyst

(2012) Daniel A. DiRocco et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbene-Catalyzed Internal Redox Reaction of Alkynals: An Efficient Synthesis of Allenoates

(2012) Yu-Ming Zhao et al.   ORGANIC LETTERS

Highly Enantioselective Cyclizations of Conjugated Trienes with Low Catalyst Loadings: A Robust Chiral N-Heterocyclic Carbene Enabled by Acetic Acid Cocatalyst

(2012) Guansai Liu et al.   ORGANIC LETTERS

Extending NHC-Catalysis: Coupling Aldehydes with Unconventional Reaction Partners

(2011) Akkattu T. Biju et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Highly Regio- and Stereoselective Cascade Annulation of Enals and Benzodi(enone)s Catalyzed by N-Heterocyclic Carbenes

(2011) Xinqiang Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Stetter Reactions of Enals and Modified Chalcones Catalyzed by N-Heterocyclic Carbenes

(2011) Xinqiang Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic Routes to N-Heterocyclic Carbene Precursors

(2011) Laure Benhamou et al.   CHEMICAL REVIEWS

Dual Secondary Amine/N-Heterocyclic Carbene Catalysis in the Asymmetric Michael/Cross-Benzoin Cascade Reaction of β-Oxo Sulfones with Enals

(2011) Dieter Enders et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Functionalization of Carboxylic Acids: Isothiourea-Catalyzed Asymmetric Intra- and Intermolecular Michael Addition−Lactonizations

(2011) Dorine Belmessieri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene and Brønsted Acid Cooperative Catalysis: Asymmetric Synthesis oftrans-γ-Lactams

(2011) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Intermolecular Stetter Reaction of Enals with Nitroalkenes: Enhancement of Catalytic Efficiency through Bifunctional Additives

(2011) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Iminium Ion/Carbene Reaction Cascade for the Formation of Optically Active 2,4-Disubstituted Cyclopentenones

(2011) Christian Borch Jacobsen et al.   ORGANIC LETTERS

Enantioselective Diels–Alder Reactions of Enals and Alkylidene Diketones Catalyzed by N-Heterocyclic Carbenes

(2011) Xinqiang Fang et al.   ORGANIC LETTERS

N-Heterocyclic carbene (NHC) catalyzed annulation of enals and vinyl ketones: a novel synthesis of [2H]-pyranones

(2011) Vijay Nair et al.   TETRAHEDRON LETTERS

Enamine/carbene cascade catalysis in the diastereo- and enantioselective synthesis of functionalized cyclopentanones

(2011) Kerem E. Ozboya et al.   Chemical Science

CooperativeN-Heterocyclic Carbene/Lewis Acid Catalysis for Highly Stereoselective Annulation Reactions with Homoenolates

(2010) Benoit Cardinal-David et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to γ-lactams

(2010) Dustin E. A. Raup et al.   Nature Chemistry

Chiral N-heterocyclic carbene-catalyzed generation of ester enolate equivalents from  , -unsaturated aldehydes for enantioselective Diels-Alder reactions

(2010) J. Kaeobamrung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NHC-catalyzed efficient synthesis of β′-amino enones via carbonyl umpolung reaction of enals with aziridines

(2010) Lal Dhar S. Yadav et al.   TETRAHEDRON LETTERS

Organocatalytic Regio- and Stereoselective Inverse-Electron-Demand Aza-Diels-Alder Reaction of α,β-Unsaturated Aldehydes andN-Tosyl-1-aza-1,3-butadienes

(2009) Bo Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly enantioselective intramolecular Michael reactions by d-camphor-derived triazolium salts

(2009) Yi Li et al.   CHEMICAL COMMUNICATIONS

N-Heterocyclic Carbene-Catalyzed Enantioselective Mannich Reactions with α-Aryloxyacetaldehydes

(2009) Yasufumi Kawanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Synthesis of Functionalized Cyclopentanones via a Multicatalytic Secondary Amine/N-Heterocyclic Carbene Catalyzed Cascade Sequence

(2009) Stephen P. Lathrop et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergency of Triazolium and Imidazolium-Derived NHCs for Catalytic, Enantioselective Cyclopentane Synthesis

(2009) Juthanat Kaeobamrung et al.   ORGANIC LETTERS

Organocatalytic Enantioselective Synthesis of Nitrogen-Substituted Dihydropyran-2-ones, a Key Synthetic Intermediate of 1β-Methylcarbapenems

(2009) Shoji Kobayashi et al.   ORGANIC LETTERS

Impact of Solvent Polarity on N-Heterocyclic Carbene-Catalyzed β-Protonations of Homoenolate Equivalents

(2009) Brooks E. Maki et al.   ORGANIC LETTERS

Carbonyl Umpolung Reactivity of Enals: NHC-Catalyzed Synthesis of Aldol Products via Epoxide Ring Opening

(2009) Lal Yadav et al.   SYNLETT

Stereoselective Synthesis of γ-ButyrolactonesviaOrganocatalytic Annulations of Enals and Keto Esters

(2008) Yi Li et al.   ADVANCED SYNTHESIS & CATALYSIS

ChiralN-Heterocyclic Carbene-Catalyzed Formal [4+2] Cycloaddition of Ketenes with Enones: Highly Enantioselective Synthesis oftrans- andcis-δ-Lactones

(2008) Yan-Rong Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Heterocyclic carbene catalysed β-lactam synthesis

(2008) Nicolas Duguet et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Assembly of Substituted Dihydropyrones via Organocatalytic Reaction in Water Media

(2008) Jing Wang et al.   ORGANIC LETTERS