Catalytic kinetic resolution of a dynamic racemate: highly stereoselective β-lactone formation by N-heterocyclic carbene catalysis

Cooperative N-Heterocyclic Carbene (NHC) and Ruthenium Redox Catalysis: Oxidative Esterification of Aldehydes with Air as the Terminal Oxidant

(2013) Junfeng Zhao et al.   ADVANCED SYNTHESIS & CATALYSIS

NHC-Catalyzed Hydroacylation of Styrenes

(2013) Michael Schedler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acyl anion free N-heterocyclic carbene organocatalysis

(2013) Sarah J. Ryan et al.   CHEMICAL SOCIETY REVIEWS

NHC-Promoted Asymmetric β-Lactone Formation from Arylalkylketenes and Electron-Deficient Benzaldehydes or Pyridinecarboxaldehydes

(2013) James Douglas et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic C–H Bond Arylation of Aldehydes to Bis-heteroaryl Ketones

(2013) Qiao Yan Toh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–H⋯O non-classical hydrogen bonding in the stereomechanics of organic transformations: theory and recognition

(2013) Ryne C. Johnston et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

NHC-Catalyzed Reaction of Enals with Hydroxy Chalcones: Diastereoselective Synthesis of Functionalized Coumarins

(2013) Anup Bhunia et al.   ORGANIC LETTERS

N-Heterocyclic Carbene Catalyzed Addition of Aldehydes to Diazo Compounds: Stereoselective Synthesis of N-Acylhydrazones

(2013) Fábio M. F. Santos et al.   ORGANIC LETTERS

Mechanistic insights into the triazolylidene-catalysed Stetter and benzoin reactions: role of the N-aryl substituent

(2013) Christopher J. Collett et al.   Chemical Science

N-Heterocyclic Carbene-Catalyzed Enantioselective Intramolecular N-Tethered Aldehyde–Ketone Benzoin Reactions

(2013) Min-Qiang Jia et al.   ACS Catalysis

Exploiting Acyl and Enol Azolium Intermediates via N-Hetero- cyclic Carbene-Catalyzed Reactions of α-Reducible Aldehydes

(2012) Harit U. Vora et al.   ADVANCED SYNTHESIS & CATALYSIS

An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones

(2012) Julien Dugal-Tessier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Cross-Aza-Benzoin Reactions of Aliphatic Aldehydes withN-Boc-Protected Imines

(2012) Daniel A. DiRocco et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Dynamic Kinetic Resolutions with N-Heterocyclic Carbenes: Asymmetric Synthesis of Highly Substituted β-Lactones

(2012) Daniel T. Cohen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism and Stereocontrol: Enantioselective Addition of Pyrrole to Ketenes Using Planar-Chiral Organocatalysts

(2012) Ommidala Pattawong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Intermolecular Stetter Reactions of Enolizable Aldehydes with Nitrostyrenes: Computational Study Provides Insight into the Success of the Catalyst

(2012) Daniel A. DiRocco et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Concise Assembly of Electron-Deficient 2,4-Dienes and 2,4-Dienals: Regio- and Stereoselectiveexo-Diels-Alder and Redox Reactions through Sequential Amine and Carbene Catalysis

(2012) Chao Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic-Carbene-Catalyzed Asymmetric Oxidative Hetero-Diels-Alder Reactions with Simple Aliphatic Aldehydes

(2012) Xiaodan Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective, NHC-Catalyzed Annulations of Trisubstituted Enals and CyclicN-Sulfonylimines via α,β-Unsaturated Acyl Azoliums

(2012) Alberto G. Kravina et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nucleophilic Addition of Enols and Enamines to α,β-Unsaturated Acyl Azoliums: Mechanistic Studies

(2012) Ramesh C. Samanta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

(2012) Javier Izquierdo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Controlled β-protonation and [4+2] cycloaddition of enals and chalconesvia N-heterocyclic carbene/acid catalysis: toward substrate independent reaction control

(2012) Zhenqian Fu et al.   CHEMICAL COMMUNICATIONS

Amidines, isothioureas, and guanidines as nucleophilic catalysts

(2012) James E. Taylor et al.   CHEMICAL SOCIETY REVIEWS

Highly Enantioselective Intermolecular Stetter Reaction of Simple Acrylates: Synthesis of α-Chiral γ-Ketoesters

(2012) Nathalie E. Wurz et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Diastereoselective, Nucleophile-Promoted Aldol-Lactonization of Ketoacids Leading to Bicyclic-β-Lactones

(2012) Gang Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

On the Organocatalytic Activity of N-Heterocyclic Carbenes: Role of Sulfur in Thiamine

(2012) Oldamur Hollóczki et al.   JOURNAL OF ORGANIC CHEMISTRY

Diastereoselective and Enantioselective Desymmetrization of α-Substituted Cyclohexadienones via Intramolecular Stetter Reaction

(2012) Min-Qiang Jia et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Catalyzed Ireland–Coates Claisen Rearrangement: Synthesis of Functionalized β-Lactones

(2012) Lisa Candish et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nonenzymatic Dynamic Kinetic Resolution of Secondary Alcohols via Enantioselective Acylation: Synthetic and Mechanistic Studies

(2012) Sarah Yunmi Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Proton Transfer Reactions of Triazol-3-ylidenes: Kinetic Acidities and Carbon Acid pKa Values for Twenty Triazolium Salts in Aqueous Solution

(2012) Richard S. Massey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxyanion Steering and CH−π Interactions as Key Elements in an N-Heterocyclic Carbene-Catalyzed [4 + 2] Cycloaddition

(2012) Scott E. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric α-Acylation of Tertiary Amines Mediated by a Dual Catalysis Mode: N-Heterocyclic Carbene and Photoredox Catalysis

(2012) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC Brønsted base-catalyzed transformations of isochromene derivatives: regulation of products by the structures of carbene catalysts

(2012) Xing-Wen Fan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Efficient Synthesis of γ-Keto Sulfones by NHC-Catalyzed Intermolecular Stetter Reaction

(2012) Anup Bhunia et al.   ORGANIC LETTERS

A Cascade Reaction Actuated by Nucleophilic Heterocyclic Carbene Catalyzed Intramolecular Addition of Enals via Homoenolate to α,β-Unsaturated Esters: Efficient Synthesis of Coumarin Derivatives

(2012) C. R. Sinu et al.   ORGANIC LETTERS

Origin of Stereoselectivity in a Chiral N-Heterocyclic Carbene-Catalyzed Desymmetrization of Substituted Cyclohexyl 1,3-Diketones

(2012) Yernaidu Reddi et al.   ORGANIC LETTERS

Access to Spirocyclic Oxindoles via N-Heterocyclic Carbene-Catalyzed Reactions of Enals and Oxindole-Derived α,β-Unsaturated Imines

(2012) Kun Jiang et al.   ORGANIC LETTERS

N-Heterocyclic Carbene (NHC)-Catalyzed Highly Diastereo- and Enantioselective Oxo-Diels–Alder Reactions for Synthesis of Fused Pyrano[2,3-b]indoles

(2012) Limin Yang et al.   ORGANIC LETTERS

Multicatalytic Asymmetric Synthesis of Complex Tetrahydrocarbazoles via a Diels–Alder/Benzoin Reaction Sequence

(2012) Yankai Liu et al.   ORGANIC LETTERS

A computational study of the origin of stereoinduction in NHC-catalyzed annulation reactions of α,β-unsaturated acyl azoliums

(2012) Eirik Lyngvi et al.   Chemical Science

Organocatalyzed Dynamic Kinetic Resolution

(2011) Hélène Pellissier   ADVANCED SYNTHESIS & CATALYSIS

Lewis Acid Activated Synthesis of Highly Substituted Cyclopentanes by the N-Heterocyclic Carbene Catalyzed Addition of Homoenolate Equivalents to Unsaturated Ketoesters

(2011) Daniel T. Cohen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of (+)-Omphadiol

(2011) Gang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonenzymatic Dynamic Kinetic Resolution of α-(Arylthio)- and α-(Alkylthio)alkanoic Acids

(2011) Xing Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic Kinetic Resolution of α-Substituted β-Ketoesters Catalyzed by Baeyer-Villiger Monooxygenases: Access to Enantiopure α-Hydroxy Esters

(2011) Ana Rioz-Martínez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Synthesis of α-Amino Acid Derivatives by an NHC-Catalyzed Intermolecular Stetter Reaction

(2011) Thierry Jousseaume et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Enantioselective Acyl Transfer onto Racemic as well as meso Alcohols, Amines, and Thiols

(2011) Christian E. Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Introduction of abnormal N-heterocyclic carbene as an efficient organocatalyst: ring opening polymerization of cyclic esters

(2011) Tamal K. Sen et al.   CHEMICAL COMMUNICATIONS

Quantum Mechanical Investigations of Organocatalysis: Mechanisms, Reactivities, and Selectivities

(2011) Paul Ha-Yeon Cheong et al.   CHEMICAL REVIEWS

Divergent reactions on racemic mixtures

(2011) Laura C. Miller et al.   CHEMICAL SOCIETY REVIEWS

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic carbene (NHC) ligands and palladium in homogeneous cross-coupling catalysis: a perfect union

(2011) George C. Fortman et al.   CHEMICAL SOCIETY REVIEWS

Insight into the Role of the Counteranion of an Imidazolium Salt in Organocatalysis: A Combined Experimental and Computational Study

(2011) Siping Wei et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Family of Thiazolium Salt Derived N-Heterocyclic Carbenes (NHCs) for Organocatalysis: Synthesis, Investigation and Application in Cross-Benzoin Condensation

(2011) Isabel Piel et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Nonenzymatic Acylative Kinetic Resolution of Racemic Amines and Related Compounds

(2011) Victor P. Krasnov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Mechanistic Insights on N-Heterocyclic Carbene-Catalyzed Annulations: The Role of Base-Assisted Proton Transfers

(2011) Pragya Verma et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthetic and Quantum Mechanical Studies into the N-Heterocyclic Carbene Catalyzed (4 + 2) Cycloaddition

(2011) Sarah J. Ryan et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Catalyzed (4 + 2) Cycloaddition/Decarboxylation of Silyl Dienol Ethers with α,β-Unsaturated Acid Fluorides

(2011) Sarah J. Ryan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantum Mechanical Investigation of the Effect of Catalyst Fluorination in the Intermolecular Asymmetric Stetter Reaction

(2011) Joann M. Um et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene and Brønsted Acid Cooperative Catalysis: Asymmetric Synthesis oftrans-γ-Lactams

(2011) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene (NHC)-Catalyzed Intermolecular Hydroacylation of Cyclopropenes

(2011) Xavier Bugaut et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Concise formal synthesis of (−)-7-deoxyloganin via N-heterocyclic carbene catalysed rearrangement of α,β-unsaturated enol esters

(2011) Lisa Candish et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Understanding the cooperative NHC/LA catalysis for stereoselective annulation reactions with homoenolates. A DFT study

(2011) Luis R. Domingo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

NHC-Catalyzed/Titanium(IV)−Mediated Highly Diastereo- and Enantioselective Dimerization of Enals

(2011) Daniel T. Cohen et al.   ORGANIC LETTERS

N-Heterocyclic Carbene Catalyzed C-Glycosylation: A Concise Approach from Stetter Reaction

(2011) Seenuvasan Vedachalam et al.   ORGANIC LETTERS

Enantioselective Diels–Alder Reactions of Enals and Alkylidene Diketones Catalyzed by N-Heterocyclic Carbenes

(2011) Xinqiang Fang et al.   ORGANIC LETTERS

Recent developments in dynamic kinetic resolution

(2011) Hélène Pellissier   TETRAHEDRON

Enamine/carbene cascade catalysis in the diastereo- and enantioselective synthesis of functionalized cyclopentanones

(2011) Kerem E. Ozboya et al.   Chemical Science

NHC-catalysed, chemoselective crossed-acyloin reactions

(2011) Christopher A. Rose et al.   Chemical Science

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

Catalytic Asymmetric Synthesis of Complex Polypropionates: Lewis Base Catalyzed Aldol Equivalents in the Synthesis of Erythronolide B

(2010) Binita Chandra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Aldol Equivalents in the Enantioselective Synthesis of the Apoptolidin C Aglycone

(2010) Thomas R. Vargo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective, Organocatalyzed, Intramolecular Aldol Lactonizations with Keto Acids Leading to Bi- and Tricyclic β-Lactones and Topology-Morphing Transformations

(2010) Carolyn A. Leverett et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

pKas of the conjugate acids of N-heterocyclic carbenes in water

(2010) Eleanor M. Higgins et al.   CHEMICAL COMMUNICATIONS

Direct and efficient N-heterocyclic carbene-catalyzed hydroxymethylation of aldehydes

(2010) Nadine Kuhl et al.   CHEMICAL COMMUNICATIONS

N-Heterocyclic Carbene-Catalyzed Conjugate Additions of Alcohols

(2010) Eric M. Phillips et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene-Catalyzed Cascade Reaction Involving the Hydroacylation of Unactivated Alkynes

(2010) Akkattu T. Biju et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to γ-lactams

(2010) Dustin E. A. Raup et al.   Nature Chemistry

Understanding the mechanism of stereoselective synthesis of cyclopentenes via N-heterocyclic carbene catalyzed reactions of enals with enones

(2010) Luis R. Domingo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic Enantioselective Total Syntheses of Bakkenolides I, J, and S: Application of a Carbene-Catalyzed Desymmetrization

(2010) Eric M. Phillips et al.   ORGANIC LETTERS

N-Heterocyclic Carbene-Catalyzed Enantioselective Mannich Reactions with α-Aryloxyacetaldehydes

(2009) Yasufumi Kawanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene-Catalyzed Hydroacylation of Unactivated Double Bonds

(2009) Keiichi Hirano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of β-Trifluoromethyl-β-lactones via NHC-Catalyzed Ketene−Ketone Cycloaddition Reactions

(2009) Xiao-Na Wang et al.   ORGANIC LETTERS

Impact of Solvent Polarity on N-Heterocyclic Carbene-Catalyzed β-Protonations of Homoenolate Equivalents

(2009) Brooks E. Maki et al.   ORGANIC LETTERS

Surveying Sterically Demanding N-Heterocyclic Carbene Ligands with Restricted Flexibility for Palladium-catalyzed Cross-Coupling Reactions

(2008) Sebastian Würtz et al.   ACCOUNTS OF CHEMICAL RESEARCH

Biomimetic Carbene-Catalyzed Oxidations of Aldehydes Using TEMPO

(2008) Joyram Guin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Heterocyclic Carbenes: Synthesis and Coordination Chemistry

(2008) F. Ekkehardt Hahn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in carbon–carbon bond-forming reactions involving homoenolates generated by NHC catalysis

(2008) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

Formal Cycloaddition of Disubstituted Ketenes with 2-Oxoaldehydes Catalyzed by Chiral N-Heterocyclic Carbenes

(2008) Lin He et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Amination of Homoenolates Catalyzed byN-Heterocyclic Carbenes

(2008) Audrey Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Diastereo- and Enantioselective Additions of Homoenolates to Nitrones Catalyzed byN-Heterocyclic Carbenes

(2008) Eric M. Phillips et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Concise Synthesis of Spirocyclic, Bridged γ-Butyrolactones via Stereospecific, Dyotropic Rearrangements of β-Lactones Involving 1,2-Acyl and δ-Lactone Migrations

(2008) Vikram C. Purohit et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC-Catalyzed Reactions of Aryloxyacetaldehydes: A Domino Elimination/Conjugate Addition/Acylation Process for the Synthesis of Substituted Coumarins

(2008) Eric M. Phillips et al.   ORGANIC LETTERS

Recent developments in dynamic kinetic resolution

(2007) Hélène Pellissier   TETRAHEDRON