The Role of IgA in the Manifestation and Prevention of Allergic Immune Responses

The role of IgA in food allergy remains elusive—timing is everything?

(2023) Antti E. Seppo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The role of retinoic acid in the production of immunoglobulin A

(2022) Amelie Bos et al.   Mucosal Immunology

Roles of Secretory Immunoglobulin A in Host-Microbiota Interactions in the Gut Ecosystem

(2022) E. Daniel León et al.   Frontiers in Microbiology

Interleukin-21, acting beyond the immunological synapse, independently controls T follicular helper and germinal center B cells

(2022) Isaak Quast et al.   IMMUNITY

Peanut-Specific IgG4 and IgA in Saliva are Modulated by Peanut Oral Immunotherapy

(2022) Johanna M. Smeekens et al.   Journal of Allergy and Clinical Immunology-In Practice

Fcα Receptor-1-Activated Monocytes Promote B Lymphocyte Migration and IgA Isotype Switching

(2022) Amélie V. Bos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Advances in IgA glycosylation and its correlation with diseases

(2022) Li Ding et al.   Frontiers in Chemistry

Food-specific immunoglobulin A does not correlate with natural tolerance to peanut or egg allergens

(2022) Elise G. Liu et al.   Science Translational Medicine

Invited review: The role of allergen‐specific IgE, IgG and IgA in allergic disease

(2021) Mohamed H. Shamji et al.   ALLERGY

Differential induction of allergen-specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy

(2021) Mohamed H. Shamji et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Wanderings of Gut-Derived IgA Plasma Cells: Impact on Systemic Immune Responses

(2021) Selina J. Keppler et al.   Frontiers in Immunology

Innate Mechanisms in Selective IgA Deficiency

(2021) Jingyan Zhang et al.   Frontiers in Immunology

Acetate differentially regulates IgA reactivity to commensal bacteria

(2021) Tadashi Takeuchi et al.   NATURE

The Epidemiology and Clinical Presentations of Atopic Diseases in Selective IgA Deficiency

(2021) Izabela Morawska et al.   Journal of Clinical Medicine

IgA subclasses have different effector functions associated with distinct glycosylation profiles

(2020) Ulrike Steffen et al.   Nature Communications

When Therapeutic IgA Antibodies Might Come of Age

(2020) Delphine Sterlin et al.   PHARMACOLOGY

9‐ cis Retinoic acid and 1.25‐dihydroxyvitamin D 3 drive differentiation into IgA + secreting plasmablasts in human naïve B cells

(2020) Sandra Treptow et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Gut microbiota–specific IgA+ B cells traffic to the CNS in active multiple sclerosis

(2020) Anne-Katrin Pröbstel et al.   Science Immunology

The Impact of Pectin Supplementation on Intestinal Barrier Function in Healthy Young Adults and Healthy Elderly

(2019) Wilms et al.   Nutrients

APRIL Induces a Novel Subset of IgA+ Regulatory B Cells That Suppress Inflammation via Expression of IL-10 and PD-L1

(2019) Cynthia M. Fehres et al.   Frontiers in Immunology

Serum IgA Fc effector functions in infectious disease and cancer

(2019) Samantha K. Davis et al.   IMMUNOLOGY AND CELL BIOLOGY

Food allergy and the microbiome: Current understandings and future directions

(2019) Supinda Bunyavanich et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human IgA binds a diverse array of commensal bacteria

(2019) Delphine Sterlin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nasal Allergen Neutralising IgG4 Antibodies Block IgE-mediated Responses: Novel biomarker of Subcutaneous Grass Pollen Immunotherapy

(2018) Mohamed H. Shamji et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lyn and Fyn function as molecular switches that control immunoreceptors to direct homeostasis or inflammation

(2017) Sanae Ben Mkaddem et al.   Nature Communications

Component-resolved analysis of IgA, IgE, and IgG4 during egg OIT identifies markers associated with sustained unresponsiveness

(2016) B. L. Wright et al.   ALLERGY

Gut Microbial Metabolites Fuel Host Antibody Responses

(2016) Myunghoo Kim et al.   Cell Host & Microbe

Microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43

(2016) W Wu et al.   Mucosal Immunology

The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins

(2016) Beth M Stadtmueller et al.   eLife

Immunoglobulin A Coating Identifies Colitogenic Bacteria in Inflammatory Bowel Disease

(2014) Noah W. Palm et al.   CELL

Retinoic acid acts as a selective human IgA switch factor

(2014) Goo-Young Seo et al.   HUMAN IMMUNOLOGY

An Indispensable Role for the Chemokine Receptor CCR10 in IgA Antibody-Secreting Cell Accumulation

(2014) O. Morteau et al.   JOURNAL OF IMMUNOLOGY

IL-21-Induced Isotype Switching to IgG and IgA by Human Naive B Cells Is Differentially Regulated by IL-4

(2014) D. T. Avery et al.   JOURNAL OF IMMUNOLOGY

Soluble immunoglobulin A in breast milk is inversely associated with atopic dermatitis at early age: the PASTURE cohort study

(2013) L. Orivuori et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Role of maternal elimination diets and human milk IgA in the development of cow's milk allergy in the infants

(2013) K. M. Järvinen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Egg-white-specific IgA and IgA2 antibodies in egg-allergic children: Is there a role in tolerance induction?

(2013) George N. Konstantinou et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Increased peanut-specific IgA levels in saliva correlate with food challenge outcomes after peanut sublingual immunotherapy

(2012) Michael Kulis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ingested allergens must be absorbed systemically to induce systemic anaphylaxis

(2011) Richard T. Strait et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Naturally Occurring Structural Isomers in Serum IgA1 O-Glycosylation

(2011) Kazuo Takahashi et al.   JOURNAL OF PROTEOME RESEARCH

Inhibitory ITAM Signaling Traps Activating Receptors with the Phosphatase SHP-1 to Form Polarized "Inhibisome" Clusters

(2011) S. Pfirsch-Maisonnas et al.   Science Signaling

Sublingual grass pollen immunotherapy is associated with increases in sublingual Foxp3-expressing cells and elevated allergen-specific immunoglobulin G4, immunoglobulin A and serum inhibitory activity for immunoglobulin E-facilitated allergen binding to B cells

(2010) G. W. Scadding et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Deglycosylation of FcαR at N58 increases its binding to IgA

(2010) Jing Xue et al.   GLYCOBIOLOGY

Selective IgA deficiency in early life: Association to infections and allergic diseases during childhood

(2009) Magdalena Janzi et al.   CLINICAL IMMUNOLOGY

High intestinal IgA associates with reduced risk of IgE-associated allergic diseases

(2009) Kaarina Kukkonen et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Analysis of IgA1N-Glycosylation and Its Contribution to FcαRI Binding†

(2008) Michelle M. Gomes et al.   BIOCHEMISTRY