Pharmacokinetic and Pharmacodynamic Obstacles for Phage Therapy From the Perspective of Clinical Practice

Pharmacokinetics/pharmacodynamics of phage therapy: a major hurdle to clinical translation

(2023) Sue C. Nang et al.   CLINICAL MICROBIOLOGY AND INFECTION

Antibiotics that affect translation can antagonize phage infectivity by interfering with the deployment of counter-defenses

(2023) Benoit J. Pons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global trends and hotspots of phage therapy for bacterial infection: A bibliometric visualized analysis from 2001 to 2021

(2023) Zulipikaer Maimaiti et al.   Frontiers in Microbiology

The applications of animal models in phage therapy: An update

(2023) Fazal Mehmood Khan et al.   Human Vaccines & Immunotherapeutics

Translating phage therapy into the clinic: Recent accomplishments but continuing challenges

(2023) Aleksandra Petrovic Fabijan et al.   PLOS BIOLOGY

Considerations for the Use of Phage Therapy in Clinical Practice

(2022) Gina A. Suh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phage therapy of wound-associated infections

(2022) Anna Zyman et al.   FOLIA MICROBIOLOGICA

The Safety and Efficacy of Phage Therapy: A Systematic Review of Clinical and Safety Trials

(2022) Helen J. Stacey et al.   Antibiotics-Basel

Modelling the synergistic effect of bacteriophage and antibiotics on bacteria: Killers and drivers of resistance evolution

(2022) Quentin J. Leclerc et al.   PLoS Computational Biology

Clinical Pharmacology of Bacteriophage Therapy: A Focus on Multidrug-Resistant Pseudomonas aeruginosa Infections

(2021) Dana Holger et al.   Antibiotics-Basel

Potent antibody-mediated neutralization limits bacteriophage treatment of a pulmonary Mycobacterium abscessus infection

(2021) Rebekah M. Dedrick et al.   NATURE MEDICINE

The Safety and Toxicity of Phage Therapy: A Review of Animal and Clinical Studies

(2021) Dan Liu et al.   Viruses-Basel

Immune Response to Therapeutic Staphylococcal Bacteriophages in Mammals: Kinetics of Induction, Immunogenic Structural Proteins, Natural and Induced Antibodies

(2021) Zuzanna Kaźmierczak et al.   Frontiers in Immunology

An Early History of Phage Therapy in the United States: Is it Time to Reconsider?

(2021) Vijay H. Aswani et al.   Clinical Medicine & Research

Analysis of the Pharmacokinetics of Suppository Forms of Bacteriophages

(2020) S. S. Bochkareva et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Topical application of bacteriophages for treatment of wound infections

(2020) Rachel Yoon Kyung Chang et al.   Translational Research

Phage Therapy in Poland – a Centennial Journey to the First Ethically Approved Treatment Facility in Europe

(2020) Maciej Żaczek et al.   Frontiers in Microbiology

Lessons Learned From the First 10 Consecutive Cases of Intravenous Bacteriophage Therapy to Treat Multidrug-Resistant Bacterial Infections at a Single Center in the United States

(2020) Saima Aslam et al.   Open Forum Infectious Diseases

Phages as immunomodulators and their promising use as anti-inflammatory agents in a cftr loss-of-function zebrafish model

(2020) Marco Cafora et al.   Journal of Cystic Fibrosis

Phage Therapy: Towards a Successful Clinical Trial

(2020) Andrzej Górski et al.   Antibiotics-Basel

Bacteriophage Interactions with Mammalian Tissue: Therapeutic Applications

(2019) Haein Huh et al.   ADVANCED DRUG DELIVERY REVIEWS

Fighting Pathogenic Bacteria on Two Fronts: Phages and Antibiotics as Combined Strategy

(2019) Thaysa Leite Tagliaferri et al.   Frontiers in Cellular and Infection Microbiology

Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review

(2019) Krystyna Dąbrowska   MEDICINAL RESEARCH REVIEWS

Safety and Tolerability of Bacteriophage Therapy for Chronic Rhinosinusitis Due to Staphylococcus aureus

(2019) Mian Li Ooi et al.   JAMA Otolaryngology-Head & Neck Surgery

Eradication of a multi-drug resistant, carbapenemase-producing Klebsiella pneumoniae isolate following oral and intra-rectal therapy with a custom-made, lytic bacteriophage preparation

(2019) Mario Corbellino et al.   CLINICAL INFECTIOUS DISEASES

Phage-specific diverse effects of bacterial viruses on the immune system

(2019) Andrzej Górski et al.   Future Microbiology

Pharmacologically Aware Phage Therapy: Pharmacodynamic and Pharmacokinetic Obstacles to Phage Antibacterial Action in Animal and Human Bodies

(2019) Krystyna Dąbrowska et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial

(2018) Patrick Jault et al.   LANCET INFECTIOUS DISEASES

Phages and immunomodulation

(2017) Andrzej Górski et al.   Future Microbiology

A bacteriophages journey through the human body

(2017) Jeremy J. Barr   IMMUNOLOGICAL REVIEWS

Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers

(2017) Sophie Nguyen et al.   mBio

Means to Facilitate the Overcoming of Gastric Juice Barrier by a Therapeutic Staphylococcal Bacteriophage A5/80

(2017) Ryszard Międzybrodzki et al.   Frontiers in Microbiology

Association of Adverse Events With Antibiotic Use in Hospitalized Patients

(2017) Pranita D. Tamma et al.   JAMA Internal Medicine

Bacteriophages as Therapeutic and Prophylactic Means: Summary of the Soviet and Post Soviet Experiences

(2016) Nina Chanishvili   Current Drug Delivery

Antibody Production in Response to Staphylococcal MS-1 Phage Cocktail in Patients Undergoing Phage Therapy

(2016) Maciej Żaczek et al.   Frontiers in Microbiology

Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh

(2016) Shafiqul Alam Sarker et al.   EBioMedicine

FDA as a catalyst for translation

(2015) Robert M. Califf et al.   Science Translational Medicine

Oral Application of T4 Phage Induces Weak Antibody Production in the Gut and in the Blood

(2015) Joanna Majewska et al.   Viruses-Basel

Mammalian Host-Versus-Phage immune response determines phage fate in vivo

(2015) Katarzyna Hodyra-Stefaniak et al.   Scientific Reports

Immunogenicity Studies of Proteins Forming the T4 Phage Head Surface

(2014) K. D browska et al.   JOURNAL OF VIROLOGY

Bacteriophage adhering to mucus provide a non-host-derived immunity

(2013) J. J. Barr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic-resistantPseudomonas aeruginosa; a preliminary report of efficacy

(2009) A. Wright et al.   CLINICAL OTOLARYNGOLOGY

Are animal models predictive for humans?

(2009) Niall Shanks et al.   Philosophy Ethics and Humanities in Medicine

Bacteriophage preparation inhibition of reactive oxygen species generation by endotoxin-stimulated polymorphonuclear leukocytes

(2007) Ryszard Miedzybrodzki et al.   VIRUS RESEARCH