Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway

A Systems Biology Approach for Addressing Cisplatin Resistance in Non-Small Cell Lung Cancer

(2023) Sravani Ramisetty et al.   Journal of Clinical Medicine

Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells

(2022) Shilpa Kuttikrishnan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Association between Incidental Pelvic Inflammation and Aggressive Prostate Cancer

(2022) Dimple Chakravarty et al.   Cancers

Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis

(2022) Shilpa Kuttikrishnan et al.   Frontiers in Oncology

Pristimerin mediated anticancer effects and sensitization of human skin cancer cells through modulation of MAPK signaling pathways

(2022) Maha Al-Tamimi et al.   BIOMEDICINE & PHARMACOTHERAPY

Guggulsterone Induces Apoptosis in Multiple Myeloma Cells by Targeting High Mobility Group Box 1 via Janus Activated Kinase/Signal Transducer and Activator of Transcription Pathway

(2022) Sabah Akhtar et al.   Cancers

Freshwater Fungi as a Source of Chemical Diversity: A Review

(2021) Tamam El-Elimat et al.   JOURNAL OF NATURAL PRODUCTS

A phase I study of anti‐BCMA CAR T cell therapy in relapsed/refractory multiple myeloma and plasma cell leukemia

(2021) Chunrui Li et al.   Clinical and Translational Medicine

Co-evolution of tumor and immune cells during progression of multiple myeloma

(2021) Ruiyang Liu et al.   Nature Communications

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway

(2021) Kirti.S. Prabhu et al.   BIOMEDICINE & PHARMACOTHERAPY

Natural resorcylic acid lactones: A chemical biology approach for anticancer activity

(2021) Shilpa Kuttikrishnan et al.   DRUG DISCOVERY TODAY

The Skp2 Pathway: A Critical Target for Cancer Therapy

(2020) Zhen Cai et al.   SEMINARS IN CANCER BIOLOGY

Skp2 depletion reduces tumor-initiating properties and promotes apoptosis in synovial sarcoma

(2020) Jichuan Wang et al.   Translational Oncology

Meroterpenoids produced by fungi: Occurrence, structural diversity, biological activities, and their molecular targets

(2020) Min Zhao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Haematology: multiple myeloma

(2019) et al.   CLINICAL MEDICINE

Meroterpenoids from Neosetophoma sp.: A Dioxa[4.3.3]propellane Ring System, Potent Cytotoxicity, and Prolific Expression

(2019) Tamam El-Elimat et al.   ORGANIC LETTERS

Shikonin derivatives for cancer prevention and therapy

(2019) Joelle C. Boulos et al.   CANCER LETTERS

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling

(2019) Sabah Akhtar et al.   Frontiers in Oncology

Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia

(2019) Shilpa Kuttikrishnan et al.   Frontiers in Oncology

Alkaloids for cancer prevention and therapy: Current progress and future perspectives

(2019) Arijit Mondal et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Repurposing dasatinib for diffuse large B cell lymphoma

(2019) Claudio Scuoppo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dramatically improved survival in multiple myeloma patients in the recent decade: results from a Swedish population-based study

(2018) Sigrun Thorsteinsdottir et al.   HAEMATOLOGICA

PKB/Akt-dependent regulation of inflammation in cancer

(2018) Fengyuan Tang et al.   SEMINARS IN CANCER BIOLOGY

Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas

(2018) Felipe C. Geyer et al.   Nature Communications

Dramatically improved survival in multiple myeloma patients in the recent decade: results from a Swedish population-based study

(2018) Sigrun Thorsteinsdottir et al.   HAEMATOLOGICA

Regulating the balance between necroptosis, apoptosis and inflammation by inhibitors of apoptosis proteins

(2017) Lazaros Vasilikos et al.   IMMUNOLOGY AND CELL BIOLOGY

Dysregulated expression of SKP2 and its role in hematological malignancies

(2017) Michal Kulinski et al.   LEUKEMIA & LYMPHOMA

Radiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1)

(2017) Karine Z. Oben et al.   PLoS One

Targeting of X-linked inhibitor of apoptosis protein and PI3-kinase/AKT signaling by embelin suppresses growth of leukemic cells

(2017) Kirti S. Prabhu et al.   PLoS One

Discovery of Anticancer Agents of Diverse Natural Origin

(2016) A. DOUGLAS KINGHORN et al.   ANTICANCER RESEARCH

Bortezomib-mediated downregulation of S-phase kinase protein-2 (SKP2) causes apoptotic cell death in chronic myelogenous leukemia cells

(2016) Ahmad Iskandarani et al.   Journal of Translational Medicine

Involvement of F-BOX proteins in progression and development of human malignancies

(2016) Shahab Uddin et al.   SEMINARS IN CANCER BIOLOGY

Mechanisms of Drug Resistance in Relapse and Refractory Multiple Myeloma

(2015) Wen-Chi Yang et al.   Biomed Research International

Overcoming bortezomib resistance in multiple myeloma

(2014) Megan Y. Murray et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis

(2012) Chia-Hsin Chan et al.   CELL

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence

(2010) Hui-Kuan Lin et al.   NATURE

Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis

(2010) Chia-Hsin Chan et al.   NATURE CELL BIOLOGY

Fatty Acid Synthase and AKT Pathway Signaling in a Subset of Papillary Thyroid Cancers

(2008) Shahab Uddin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM