Three‐dimensional bioprinting of stem cell‐derived central nervous system cells enables astrocyte growth, vasculogenesis, and enhances neural differentiation/function

Modeling angiogenesis in the human brain in a tissue-engineered post-capillary venule

(2023) Nan Zhao et al.   ANGIOGENESIS

Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells

(2022) Toshiki Kurosawa et al.   PHARMACEUTICAL RESEARCH

Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate

(2021) Tyler M. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells: Current Controversies

(2021) Tyler M. Lu et al.   Frontiers in Physiology

A Covalently Crosslinked Ink for Multimaterials Drop‐on‐Demand 3D Bioprinting of 3D Cell Cultures

(2021) Robert H. Utama et al.   MACROMOLECULAR BIOSCIENCE

Control of Astrocyte Quiescence and Activation in a Synthetic Brain Hydrogel

(2020) Sualyneth Galarza et al.   Advanced Healthcare Materials

Controlling neuronal cell growth through composite laminin supramolecular hydrogels

(2020) Rashmi Jain et al.   ACS Biomaterials-Science & Engineering

3D Bioprinting Pluripotent Stem Cell Derived Neural Tissues Using a Novel Fibrin Bioink Containing Drug Releasing Microspheres

(2020) Ruchi Sharma et al.   Frontiers in Bioengineering and Biotechnology

A primary neural cell culture model to study neuron, astrocyte, and microglia interactions in neuroinflammation

(2020) Noah Goshi et al.   Journal of Neuroinflammation

EZcalcium: Open-Source Toolbox for Analysis of Calcium Imaging Data

(2020) Daniel A. Cantu et al.   Frontiers in Neural Circuits

Synthetic alternatives to Matrigel

(2020) Elizabeth A. Aisenbrey et al.   Nature Reviews Materials

Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes

(2020) Joel W. Blanchard et al.   NATURE MEDICINE

The Role of Astrocytes in CNS Inflammation

(2020) Federico Giovannoni et al.   TRENDS IN IMMUNOLOGY

Hydrogels for Bioprinting: A Systematic Review of Hydrogels Synthesis, Bioprinting Parameters, and Bioprinted Structures Behavior

(2020) Enrique Mancha Sánchez et al.   Frontiers in Bioengineering and Biotechnology

Expanding and optimizing 3D bioprinting capabilities using complementary network bioinks

(2020) Liliang Ouyang et al.   Science Advances

A 3D Bioprinter Specifically Designed for the High-Throughput Production of Matrix-Embedded Multicellular Spheroids

(2020) Robert H. Utama et al.   iScience

Peptide-modified, hyaluronic acid-based hydrogels as a 3D culture platform for neural stem/progenitor cell engineering

(2019) Stephanie K. Seidlits et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Engineering Stem Cell Self-organization to Build Better Organoids

(2019) Jonathan A. Brassard et al.   Cell Stem Cell

A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cells from Human iPSCs

(2019) Emma H. Neal et al.   Stem Cell Reports

Questions and (some) answers on reactive astrocytes

(2019) Carole Escartin et al.   GLIA

3D Bioprinted Human Cortical Neural Constructs Derived from Induced Pluripotent Stem Cells

(2019) Salaris et al.   Journal of Clinical Medicine

Cell-instructive pectin hydrogels crosslinked via thiol-norbornene photo-click chemistry for skin tissue engineering

(2018) Rúben F. Pereira et al.   Acta Biomaterialia

Neural stem cell encapsulation and differentiation in strain promoted crosslinked polyethylene glycol-based hydrogels

(2018) Hang Li et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Evaluation of RGD functionalization in hybrid hydrogels as 3D neural stem cell culture systems

(2018) Emanuele Mauri et al.   Biomaterials Science

Animal models of neurodegenerative diseases

(2018) Ted M. Dawson et al.   NATURE NEUROSCIENCE

Three-dimensional neural cultures produce networks that mimic native brain activity

(2017) Justin L. Bourke et al.   Journal of Tissue Engineering and Regenerative Medicine

Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2017) Valery L Feigin et al.   LANCET NEUROLOGY

Cell diversity and network dynamics in photosensitive human brain organoids

(2017) Giorgia Quadrato et al.   NATURE

The use of brain organoids to investigate neural development and disease

(2017) Elizabeth Di Lullo et al.   NATURE REVIEWS NEUROSCIENCE

Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin

(2017) Be’eri Niego et al.   PLoS One

Functional characterization of human pluripotent stem cell-derived arterial endothelial cells

(2017) Jue Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis

(2017) Jiahui Cao et al.   Nature Communications

Tubulogenesis of co-cultured human iPS-derived endothelial cells and human mesenchymal stem cells in fibrin and gelatin methacrylate gels

(2017) G. A. Calderon et al.   Biomaterials Science

An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells

(2017) Julia TCW et al.   Stem Cell Reports

Brain stiffness increases with myelin content

(2016) J. Weickenmeier et al.   Acta Biomaterialia

Alzheimer’s disease: experimental models and reality

(2016) Eleanor Drummond et al.   ACTA NEUROPATHOLOGICA

Human astrocytes develop physiological morphology and remain quiescent in a novel 3D matrix

(2015) Amanda L. Placone et al.   BIOMATERIALS

Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro

(2015) Cedric Bardy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3D in vitro modeling of the central nervous system

(2015) Amy M. Hopkins et al.   PROGRESS IN NEUROBIOLOGY

Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin

(2015) Sabine Pellett et al.   Scientific Reports

From 2D to 3D: novel nanostructured scaffolds to investigate signalling in reconstructed neuronal networks

(2015) Susanna Bosi et al.   Scientific Reports

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

A three-dimensional human neural cell culture model of Alzheimer’s disease

(2014) Se Hoon Choi et al.   NATURE

Generation of cerebral organoids from human pluripotent stem cells

(2014) Madeline A Lancaster et al.   Nature Protocols

Review of Collagen I Hydrogels for Bioengineered Tissue Microenvironments: Characterization of Mechanics, Structure, and Transport

(2014) Elizabeth E. Antoine et al.   TISSUE ENGINEERING PART B-REVIEWS

Animal models of CNS disorders

(2013) Paul McGonigle   BIOCHEMICAL PHARMACOLOGY

ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1+ mesodermal precursor cells

(2012) H. J. Joo et al.   BLOOD

Ketamine Inhibits Lipopolysaccharide-Induced Astrocytes Activation by Suppressing TLR4/NF-?B Pathway

(2012) Yuqing Wu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The impact of laminin on 3D neurite extension in collagen gels

(2012) Katelyn E Swindle-Reilly et al.   Journal of Neural Engineering

Enhanced proliferation of neural stem cells in a collagen hydrogel incorporating engineered epidermal growth factor

(2011) Edgar Y. Egawa et al.   BIOMATERIALS

Bioactive modification of poly(ethylene glycol) hydrogels for tissue engineering

(2010) Junmin Zhu   BIOMATERIALS

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways

(2010) Roser Gorina et al.   GLIA

Human embryonic stem cell-derived neuronal cells form spontaneously active neuronal networks in vitro

(2009) Teemu J. Heikkilä et al.   EXPERIMENTAL NEUROLOGY