Modeling angiogenesis in the human brain in a tissue-engineered post-capillary venule

Engineering the Human Blood‐Brain Barrier at the Capillary Scale using a Double‐Templating Technique

(2022) Nan Zhao et al.   ADVANCED FUNCTIONAL MATERIALS

Oxygen gradients dictate angiogenesis but not barriergenesis in a 3D brain microvascular model

(2022) Kiet A. Tran et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Three-dimensional microenvironment regulates gene expression, function, and tight junction dynamics of iPSC-derived blood–brain barrier microvessels

(2022) Raleigh M. Linville et al.   Fluids and Barriers of the CNS

The Role of Venous Endothelial Cells in Developmental and Pathologic Angiogenesis

(2021) Heon-Woo Lee et al.   CIRCULATION

Imaging the construction of capillary networks in the neonatal mouse brain

(2021) Vanessa Coelho-Santos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Next-generation in vitro blood–brain barrier models: benchmarking and improving model accuracy

(2021) Raleigh M. Linville et al.   Fluids and Barriers of the CNS

A tissue-engineered 3D microvessel model reveals the dynamics of mosaic vessel formation in breast cancer

(2020) Vanesa L. Silvestri et al.   CANCER RESEARCH

Long-Term Cryopreservation Preserves Blood–Brain Barrier Phenotype of iPSC-Derived Brain Microvascular Endothelial Cells and Three-Dimensional Microvessels

(2020) Raleigh M. Linville et al.   MOLECULAR PHARMACEUTICS

Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA

(2020) Kai Wang et al.   Science Advances

Commentary on human pluripotent stem cell-based blood–brain barrier models

(2020) Ethan S. Lippmann et al.   Fluids and Barriers of the CNS

Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties

(2019) Matthew J. Stebbins et al.   Science Advances

Cerebrovascular plasticity: Processes that lead to changes in the architecture of brain microvessels

(2019) Max I Bogorad et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D

(2019) John J. Jamieson et al.   Fluids and Barriers of the CNS

Pericytes enable effective angiogenesis in the presence of proinflammatory signals

(2019) Tae-Yun Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes

(2018) Marco Campisi et al.   BIOMATERIALS

Neurovascular Communication during CNS Development

(2018) Isidora Paredes et al.   DEVELOPMENTAL CELL

FACS isolation of endothelial cells and pericytes from mouse brain microregions

(2018) Elizabeth E Crouch et al.   Nature Protocols

Blood-brain barrier dysfunction and recovery after ischemic stroke

(2018) Xiaoyan Jiang et al.   PROGRESS IN NEUROBIOLOGY

A 3D in vitro pericyte-supported microvessel model: visualisation and quantitative characterisation of multistep angiogenesis

(2018) Eujin Lee et al.   Journal of Materials Chemistry B

Basement membrane and stroke

(2018) Yao Yao   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior

(2018) Raleigh M. Linville et al.   BIOMATERIALS

Blood-Brain Barrier: From Physiology to Disease and Back

(2018) Melanie D. Sweeney et al.   PHYSIOLOGICAL REVIEWS

Response of the cerebral vasculature following traumatic brain injury

(2017) Arjang Salehi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CD146 coordinates brain endothelial cell–pericyte communication for blood–brain barrier development

(2017) Jianan Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vascular endothelial growth factor: a neurovascular target in neurological diseases

(2016) Christian Lange et al.   Nature Reviews Neurology

A quantitative microfluidic angiogenesis screen for studying anti-angiogenic therapeutic drugs

(2015) Choong Kim et al.   LAB ON A CHIP

Vascularisation of the central nervous system

(2015) Mathew Tata et al.   MECHANISMS OF DEVELOPMENT

Engineering of a Biomimetic Pericyte-Covered 3D Microvascular Network

(2015) Jaerim Kim et al.   PLoS One

A microfluidic platform for quantitative analysis of cancer angiogenesis and intravasation

(2014) Hyunjae Lee et al.   Biomicrofluidics

Quantitative assessment of angiogenesis, perfused blood vessels and endothelial tip cells in the postnatal mouse brain

(2014) Thomas Wälchli et al.   Nature Protocols

Fluid shear stress threshold regulates angiogenic sprouting

(2014) P. A. Galie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arteries are formed by vein-derived endothelial tip cells

(2014) Cong Xu et al.   Nature Communications

Recapitulating physiological and pathological shear stress and oxygen to model vasculature in health and disease

(2014) Hasan Erbil Abaci et al.   Scientific Reports

Engineering of functional, perfusable 3D microvascular networks on a chip

(2013) Sudong Kim et al.   LAB ON A CHIP

Formation of microvascular networks in vitro

(2013) John P Morgan et al.   Nature Protocols

Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro

(2013) D.-H. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nogo-A is a negative regulator of CNS angiogenesis

(2013) T. Walchli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tubeless microfluidic angiogenesis assay with three-dimensional endothelial-lined microvessels

(2012) Lauren L. Bischel et al.   BIOMATERIALS

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

(2012) Ethan S Lippmann et al.   NATURE BIOTECHNOLOGY

In vitro microvessels for the study of angiogenesis and thrombosis

(2012) Y. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Arterial-venous network formation during brain vascularization involves hemodynamic regulation of chemokine signaling

(2011) J. Bussmann et al.   DEVELOPMENT

In vitro 3D collective sprouting angiogenesis under orchestrated ANG-1 and VEGF gradients

(2011) Yoojin Shin et al.   LAB ON A CHIP

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Effect of mechanical factors on the function of engineered human blood microvessels in microfluidic collagen gels

(2010) Gavrielle M. Price et al.   BIOMATERIALS

The perivascular astroglial sheath provides a complete covering of the brain microvessels: An electron microscopic 3D reconstruction

(2010) Thomas Misje Mathiisen et al.   GLIA

Coronary arteries form by developmental reprogramming of venous cells

(2010) Kristy Red-Horse et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury

(2010) Dan Shlosberg et al.   Nature Reviews Neurology

Angiogenesis: A Team Effort Coordinated by Notch

(2009) L.-K. Phng et al.   DEVELOPMENTAL CELL

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE