Structure-Guided Design and Synthesis of ATP-competitive NAcyl-substituted Sulfamide D-Alanine-D-Alanine Ligase Inhibitors

Synthesis of 1-Aryltetralins via Re2O7/HReO4 Mediated Intramolecular Hydroarylations

(2023) Rukhsar Gul et al.   JOURNAL OF ORGANIC CHEMISTRY

An antimony-phosphomolybdate microassay of ATPase activity through the detection of inorganic phosphate

(2021) Jordan L. Pederick et al.   ANALYTICAL BIOCHEMISTRY

Discovery of novel antibacterial agents: Recent developments in D‐alanyl‐D‐alanine ligase inhibitors

(2021) Yinhui Qin et al.   Chemical Biology & Drug Design

D-alanine-D-alanine ligase as a model for the activation of ATP-grasp enzymes by monovalent cations

(2020) Jordan L Pederick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integron gene cassettes harboring novel variants of d-alanine-d-alanine ligase confer high-level resistance to d-cycloserine

(2020) Md. Ajijur Rahman et al.   Scientific Reports

Burkholderia pseudomallei d ‐alanine‐ d ‐alanine ligase; detailed characterisation and assessment of a potential antibiotic drug target

(2019) Laura Díaz‐Sáez et al.   FEBS Journal

Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads

(2019) Kwang Jun Lee et al.   ACS Chemical Biology

MX2: a high-flux undulator microfocus beamline serving both the chemical and macromolecular crystallography communities at the Australian Synchrotron

(2018) David Aragão et al.   JOURNAL OF SYNCHROTRON RADIATION

1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio

(2018) Alice Ameryckx et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Analysis of the clinical antibacterial and antituberculosis pipeline

(2018) Ursula Theuretzbacher et al.   LANCET INFECTIOUS DISEASES

Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

(2017) Sarah Batson et al.   Nature Communications

D-Cycloserine in Neuropsychiatric Diseases: A Systematic Review

(2015) Sebastian Schade et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Design and synthesis of 3-isoxazolidone derivatives as new Chlamydia trachomatis inhibitors

(2014) S. Abdelsayed et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis

(2013) Gareth A. Prosser et al.   ACS Medicinal Chemistry Letters

Electron Transfer Reduction of Carboxylic Acids Using SmI2–H2O–Et3N

(2012) Michal Szostak et al.   ORGANIC LETTERS

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Challenges of antibacterial discovery revisited

(2010) Michael N. Gwynn et al.   Annals of the New York Academy of Sciences

Bisubstrate Inhibitors of Protein Kinases: from Principle to Practical Applications

(2009) Darja Lavogina et al.   ChemMedChem

DD-Ligases as a Potential Target for Antibiotics: Past, Present and Future

(2009) I. Tytgat et al.   CURRENT MEDICINAL CHEMISTRY

Synthesis and Anticonvulsant Activity of Amino Acid-Derived Sulfamides

(2009) Luciana Gavernet et al.   JOURNAL OF MEDICINAL CHEMISTRY