Integron gene cassettes harboring novel variants of d-alanine-d-alanine ligase confer high-level resistance to d-cycloserine

Antimicrobial Activity of a New Class of Phosphorylated and Modified Flavonoids

(2019) Francis J. Osonga et al.   ACS Omega

Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes

(2019) Dimitrios Evangelopoulos et al.   Nature Communications

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

(2018) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Understanding the mechanisms and drivers of antimicrobial resistance

(2016) Alison H Holmes et al.   LANCET

Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance

(2016) Christopher A Desjardins et al.   NATURE GENETICS

Detection of Novel Integrons in the Metagenome of Human Saliva

(2016) Supathep Tansirichaiya et al.   PLoS One

The basics of thiols and cysteines in redox biology and chemistry

(2015) Leslie B. Poole   FREE RADICAL BIOLOGY AND MEDICINE

I-TASSER server: new development for protein structure and function predictions

(2015) Jianyi Yang et al.   NUCLEIC ACIDS RESEARCH

Treponema pallidumPutative Novel Drug Target Identification and Validation: Rethinking Syphilis Therapeutics with Plant-Derived Terpenoids

(2015) Upendra N. Dwivedi et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Integrons: Past, Present, and Future

(2014) Michael R. Gillings   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Bacterial phylogeny structures soil resistomes across habitats

(2014) Kevin J. Forsberg et al.   NATURE

The gain and loss of chromosomal integron systems in the Treponema species

(2013) Yu-Wei Wu et al.   BMC EVOLUTIONARY BIOLOGY

Characterization of Escherichia coli D-Cycloserine Transport and Resistant Mutants

(2013) G. Baisa et al.   JOURNAL OF BACTERIOLOGY

Lessons Learned in Empirical Scoring with smina from the CSAR 2011 Benchmarking Exercise

(2013) David Ryan Koes et al.   Journal of Chemical Information and Modeling

Metabolomics Analysis Identifies d-Alanine-d-Alanine Ligase as the Primary Lethal Target of d-Cycloserine in Mycobacteria

(2013) Steven Halouska et al.   JOURNAL OF PROTEOME RESEARCH

Genome-Wide Relatedness of Treponema pedis, from Gingiva and Necrotic Skin Lesions of Pigs, with the Human Oral Pathogen Treponema denticola

(2013) Olov Svartström et al.   PLoS One

Whole Genome Sequencing Reveals Complex Evolution Patterns of Multidrug-Resistant Mycobacterium tuberculosis Beijing Strains in Patients

(2013) Matthias Merker et al.   PLoS One

Pediatric Fecal Microbiota Harbor Diverse and Novel Antibiotic Resistance Genes

(2013) Aimée M. Moore et al.   PLoS One

Oral Spirochetes Implicated in Dental Diseases Are Widespread in Normal Human Subjects and Carry Extremely Diverse Integron Gene Cassettes

(2012) Yu-Wei Wu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Structural and Functional Characterization of VanG d-Ala:d-Ser Ligase Associated with Vancomycin Resistance inEnterococcus faecalis

(2012) Djalal Meziane-Cherif et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

6-Arylpyrido[2,3-d]pyrimidines as Novel ATP-Competitive Inhibitors of Bacterial D-Alanine:D-Alanine Ligase

(2012) Veronika Škedelj et al.   PLoS One

The Shared Antibiotic Resistome of Soil Bacteria and Human Pathogens

(2012) K. J. Forsberg et al.   SCIENCE

Tackling antibiotic resistance

(2011) Karen Bush et al.   NATURE REVIEWS MICROBIOLOGY

Horizontal Transfer, Not Duplication, Drives the Expansion of Protein Families in Prokaryotes

(2011) Todd J. Treangen et al.   PLoS Genetics

Integrons

(2010) Guillaume Cambray et al.   Annual Review of Genetics

Structure of theMycobacterium tuberculosisd-Alanine:d-Alanine Ligase, a Target of the Antituberculosis Drug d-Cycloserine

(2010) John B. Bruning et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Virulence Factors of the Oral Spirochete Treponema denticola

(2010) S.G. Dashper et al.   JOURNAL OF DENTAL RESEARCH

Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis

(2010) José A Caminero et al.   LANCET INFECTIOUS DISEASES

DD-Ligases as a Potential Target for Antibiotics: Past, Present and Future

(2009) I. Tytgat et al.   CURRENT MEDICINAL CHEMISTRY

Functional Characterization of the Antibiotic Resistance Reservoir in the Human Microflora

(2009) M. O. A. Sommer et al.   SCIENCE

The SOS Response Controls Integron Recombination

(2009) E. Guerin et al.   SCIENCE

d-Alanine:d-alanine ligase as a new target for the flavonoids quercetin and apigenin

(2008) Dalei Wu et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS