Formulation and Preclinical Testing of Tc-99m-Labeled HYNIC-Glc-FAPT as a FAP-Targeting Tumor Radiotracer

Design, Synthesis and Preclinical Assessment of 99mTc-iFAP for In Vivo Fibroblast Activation Protein (FAP) Imaging

(2022) Diana Trujillo-Benítez et al.   MOLECULES

Automatic Production and Preliminary PET Imaging of a New Imaging Agent [18F]AlF-FAPT

(2022) JiaWen Huang et al.   Frontiers in Oncology

Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy

(2022) Dirk Zboralski et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Chemical (neo)glycosylation of biological drugs

(2021) Raoul Walther et al.   ADVANCED DRUG DELIVERY REVIEWS

Chemical Synthesis of Antibody–Hapten Conjugates Capable of Recruiting the Endogenous Antibody to Magnify the Fc Effector Immunity of Antibody for Cancer Immunotherapy

(2021) Kun Zhou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Preparation and Bioevaluation of 99mTc-Labeled FAP Inhibitors as Tumor Radiotracers to Target the Fibroblast Activation Protein

(2021) Qing Ruan et al.   MOLECULAR PHARMACEUTICS

Preparation and evaluation of 99mTc-labeled HYNIC-palbociclib analogs for cyclin-dependent kinase 4/6-positive tumor imaging

(2020) Qianqian Gan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and development of 99mTc labeled FAPI-tracers for SPECT-imaging and 188Re therapy.

(2020) Thomas Lindner et al.   JOURNAL OF NUCLEAR MEDICINE

Design, synthesis, radiolabeling and biological evaluation of new urea-based peptides targeting prostate specific membrane antigen

(2020) Mona Mosayebnia et al.   BIOORGANIC CHEMISTRY

Impact of Primary Staging with Fibroblast Activation Protein Specific Enzyme Inhibitor (FAPI)-PET/CT on Radio-Oncologic Treatment Planning of Patients with Esophageal Cancer

(2020) J. Ristau et al.   MOLECULAR IMAGING AND BIOLOGY

O-GlcNAc Engineering of GPCR Peptide-Agonists Improves Their Stability and in Vivo Activity

(2019) Paul M. Levine et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effects of linker amino acids on the potency and selectivity of dimeric antimicrobial peptides

(2018) Ming Kai et al.   CHINESE CHEMICAL LETTERS

An improved 99m Tc-HYNIC-(Ser) 3 -LTVSPWY peptide with EDDA/tricine as co-ligands for targeting and imaging of HER2 overexpression tumor

(2018) Fatemeh Khodadust et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Development of quinoline based theranostic ligands for the targeting of fibroblast activation protein

(2018) Thomas Lindner et al.   JOURNAL OF NUCLEAR MEDICINE

A new method for tumor imaging by targeting cancer associated fibroblasts

(2018) Anastasia Loktev et al.   JOURNAL OF NUCLEAR MEDICINE

Teaming Up for Trouble: Cancer Cells, Transforming Growth Factor-β1 Signaling and the Epigenetic Corruption of Stromal Naïve Fibroblasts

(2018) Sergio Lamprecht et al.   Cancers

FAPI-PET/CT: biodistribution and preliminary dosimetry estimate of two DOTA-containing FAP-targeting agents in patients with various cancers

(2018) Frederik Giesel et al.   JOURNAL OF NUCLEAR MEDICINE

The Mechanistic Impact of N-Glycosylation on Stability, Pharmacokinetics, and Immunogenicity of Therapeutic Proteins

(2018) Qun Zhou et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

SPECT/CT Imaging of the Novel HER2-Targeted Peptide Probe99mTc-HYNIC-H6F in Breast Cancer Mouse Models

(2017) Liqiang Li et al.   JOURNAL OF NUCLEAR MEDICINE

‘4+1’ Mixed Ligand Strategy for the Preparation of 99m Tc-Radiopharmaceuticals for Hypoxia Detecting Applications

(2017) Kusum Vats et al.   ChemistrySelect

Modulation of in vivo distribution through chelator: Synthesis and evaluation of a 2-nitroimidazole–dipicolylamine–99mTc(CO)3 complex for detecting tumor hypoxia

(2016) Madhava B. Mallia et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthetic nanoparticles camouflaged with biomimetic erythrocyte membranes for reduced reticuloendothelial system uptake

(2016) Lang Rao et al.   NANOTECHNOLOGY

Semisynthesis of Biologically Active Glycoforms of the Human Cytokine Interleukin 6

(2014) Andreas Reif et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PEG — A versatile conjugating ligand for drugs and drug delivery systems

(2014) Atul Kolate et al.   JOURNAL OF CONTROLLED RELEASE

Novel 99mTc radiolabeled folate complexes with PEG linkers for FR-positive tumor imaging: synthesis and biological evaluation

(2014) Fang Xie et al.   RSC Advances

Rationale Behind Targeting Fibroblast Activation Protein-Expressing Carcinoma-Associated Fibroblasts as a Novel Chemotherapeutic Strategy

(2012) W. N. Brennen et al.   MOLECULAR CANCER THERAPEUTICS

Effect of a second nitroimidazole redox centre on the accumulation of a hypoxia marker: Synthesis and in vitro evaluation of 99mTc-labeled bisnitroimidazole propylene amine oxime complexes

(2011) Huafan Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

99mTc-HYNIC-Gastrin Peptides: Assisted Coordination of 99mTc by Amino Acid Side Chains Results in Improved Performance Both In Vitro and In Vivo

(2009) R. King et al.   JOURNAL OF NUCLEAR MEDICINE