Evolutionary perspective on mammalian inorganic polyphosphate (polyP) biology

The emerging landscape of eukaryotic polyphosphatases

(2023) Liam McCarthy et al.   FEBS LETTERS

Nucleolar Architecture Is Modulated by a Small Molecule, the Inositol Pyrophosphate 5-InsP7

(2023) Soumyadip Sahu et al.   Biomolecules

Cryo‐EM structure of the polyphosphate polymerase VTC reveals coupling of polymer synthesis to membrane transit

(2023) Wei Liu et al.   EMBO JOURNAL

Starvation Induces Extracellular Accumulation of Polyphosphate in Dictyostelium discoideum to Inhibit Macropinocytosis, Phagocytosis, and Exocytosis

(2023) Ramesh Rijal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A phosphate-sensing organelle regulates phosphate and tissue homeostasis

(2023) Chiwei Xu et al.   NATURE

The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex

(2023) Zeyuan Guan et al.   Nature Communications

The basics of phosphate metabolism

(2023) Carsten A Wagner   NEPHROLOGY DIALYSIS TRANSPLANTATION

Mitochondrial Inorganic Polyphosphate (polyP) Is a Potent Regulator of Mammalian Bioenergetics in SH-SY5Y Cells: A Proteomics and Metabolomics Study

(2022) Mariona Guitart-Mampel et al.   Frontiers in Cell and Developmental Biology

Effects of ex vivo blood anticoagulation and preanalytical processing time on the proteome content of platelets

(2022) Samuel Tassi Yunga et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Enzymatic Depletion of Mitochondrial Inorganic Polyphosphate (polyP) Increases the Generation of Reactive Oxygen Species (ROS) and the Activity of the Pentose Phosphate Pathway (PPP) in Mammalian Cells

(2022) Vedangi Hambardikar et al.   Antioxidants

Inorganic Polyphosphate—Regulator of Cellular Metabolism in Homeostasis and Disease

(2022) Filip Kus et al.   Biomedicines

Ddp1 Cooperates with Ppx1 to Counter a Stress Response Initiated by Nonvacuolar Polyphosphate

(2022) Liam McCarthy et al.   mBio

Phase separation of DNA: from past to present

(2021) John T. King et al.   BIOPHYSICAL JOURNAL

Depletion of mitochondrial inorganic polyphosphate (polyP) in mammalian cells causes metabolic shift from oxidative phosphorylation to glycolysis

(2021) Maria E. Solesio et al.   BIOCHEMICAL JOURNAL

The chemistry of branched condensed phosphates

(2021) Tobias Dürr-Mayer et al.   Nature Communications

Polyphosphate degradation by Nudt3-Zn2+ mediates oxidative stress response

(2021) Bàrbara Samper-Martín et al.   Cell Reports

Polyphosphate Kinase 1 Is a Pathogenesis Determinant in Enterohemorrhagic Escherichia coli O157:H7

(2021) Yanli Du et al.   Frontiers in Microbiology

The inositol pyrophosphate metabolism of Dictyostelium discoideum does not regulate inorganic polyphosphate (polyP) synthesis

(2021) Yann Desfougères et al.   Advances in Biological Regulation

Inorganic polyphosphate in mammals: where's Wally?

(2020) Yann Desfougères et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The nucleolus as a multiphase liquid condensate

(2020) Denis L. J. Lafontaine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse organs

(2019) Askar Yimit et al.   Nature Communications

A stringent analysis of polyphosphate dynamics in E. coli

(2019) Michael Downey   JOURNAL OF BACTERIOLOGY

Progress and Applications of Polyphosphate in Bone and Cartilage Regeneration

(2019) Yan Wang et al.   Biomed Research International

An Inorganic Biopolymer Polyphosphate Controls Positively Charged Protein Phase Transitions

(2019) Jing Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inorganic Polyphosphates As Storage for and Generator of Metabolic Energy in the Extracellular Matrix

(2019) Werner E.G. Müller et al.   CHEMICAL REVIEWS

Inorganic polyphosphate is required for sustained free mitochondrial calcium elevation, following calcium uptake

(2019) Maria E. Solesio et al.   CELL CALCIUM

Accumulation of Nucleolar Inorganic Polyphosphate Is a Cellular Response to Cisplatin-Induced Apoptosis

(2019) Lihan Xie et al.   Frontiers in Oncology

Screening a Protein Array with Synthetic Biotinylated Inorganic Polyphosphate To Define the Human PolyP-ome

(2018) Cristina Azevedo et al.   ACS Chemical Biology

A Screen for Candidate Targets of Lysine Polyphosphorylation Uncovers a Conserved Network Implicated in Ribosome Biogenesis

(2018) Amanda Bentley-DeSousa et al.   Cell Reports

Distribution Patterns of Polyphosphate Metabolism Pathway and Its Relationships With Bacterial Durability and Virulence

(2018) Liang Wang et al.   Frontiers in Microbiology

Inorganic polyphosphate, a multifunctional polyanionic protein scaffold

(2018) Lihan Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Eukaryotic Phosphate Homeostasis: The Inositol Pyrophosphate Perspective

(2017) Cristina Azevedo et al.   TRENDS IN BIOCHEMICAL SCIENCES

The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction

(2017) Thomas Knöpfel et al.   Scientific Reports

Enzymes of yeast polyphosphate metabolism: structure, enzymology and biological roles

(2016) R. Gerasimaite et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

Polyphosphate: popping up from oblivion

(2016) Javier Jiménez et al.   CURRENT GENETICS

Extracellular Polyphosphate Inhibits Proliferation in an Autocrine Negative Feedback Loop inDictyostelium discoideum

(2016) Patrick M. Suess et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyphosphate: A Conserved Modifier of Amyloidogenic Processes

(2016) Claudia M. Cremers et al.   MOLECULAR CELL

Developmental accumulation of inorganic polyphosphate affects germination and energetic metabolism inDictyostelium discoideum

(2016) Thomas Miles Livermore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondria and Iron: current questions

(2016) Bibbin T. Paul et al.   Expert Review of Hematology

The mitochondrial phosphate carrier: Role in oxidative metabolism, calcium handling and mitochondrial disease

(2015) Erin L. Seifert et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inositol pyrophosphates regulate RNA polymerase I-mediated rRNA transcription inSaccharomyces cerevisiae

(2015) Swarna Gowri Thota et al.   BIOCHEMICAL JOURNAL

Structure and function of mitochondrial membrane protein complexes

(2015) Werner Kühlbrandt   BMC BIOLOGY

Redox Homeostasis and Mitochondrial Dynamics

(2015) Peter H.G.M. Willems et al.   Cell Metabolism

Endosymbiosis and Eukaryotic Cell Evolution

(2015) John M. Archibald   CURRENT BIOLOGY

Oxidative stress protection by polyphosphate—new roles for an old player

(2015) Michael J Gray et al.   CURRENT OPINION IN MICROBIOLOGY

Polyphosphate as modulator of hemostasis, thrombosis, and inflammation

(2015) J. H. Morrissey et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Protein Polyphosphorylation of Lysine Residues by Inorganic Polyphosphate

(2015) Cristina Azevedo et al.   MOLECULAR CELL

Lysine post-translational modifications and the cytoskeleton: Figure 1.

(2014) Wendy D. Zencheck et al.   Essays in Biochemistry

Coupled synthesis and translocation restrains polyphosphate to acidocalcisome-like vacuoles and prevents its toxicity

(2014) R. Gerasimaite et al.   JOURNAL OF CELL SCIENCE

Eukaryotic Origins: How and When Was the Mitochondrion Acquired?

(2014) A. M. Poole et al.   Cold Spring Harbor Perspectives in Biology

Inositol pyrophosphates: between signalling and metabolism

(2013) Miranda S. C. Wilson et al.   BIOCHEMICAL JOURNAL

Deoxynucleoside triphosphate (dNTP) synthesis and destruction regulate the replication of both cell and virus genomes

(2013) B. Stillman   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myeloma cells contain high levels of inorganic polyphosphate which is associated with nucleolar transcription

(2012) M. D. Jimenez-Nunez et al.   HAEMATOLOGICA

Identification of an Evolutionarily Conserved Family of Inorganic Polyphosphate Endopolyphosphatases

(2011) Annalisa Lonetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization and prediction of protein nucleolar localization sequences

(2010) Michelle S. Scott et al.   NUCLEIC ACIDS RESEARCH

Genetic Interaction between Ribosome Biogenesis and Inositol Polyphosphate Metabolism inSaccharomyces cerevisiae

(2009) Chihiro HORIGOME et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Are inositolpyrophosphates signalling molecules?

(2009) Adam Burton et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inorganic Polyphosphate Modulates TRPM8 Channels

(2009) Eleonora Zakharian et al.   PLoS One