Gasotransmitter research advances in respiratory diseases

Toward a Predict and Prevent Approach in Obstructive Airway Diseases

(2023) Simon Couillard et al.   Journal of Allergy and Clinical Immunology-In Practice

Nitric oxide releasing nanoparticles reduce inflammation in a small animal model of ARDS

(2022) Vinay P. Jani et al.   BIOMEDICINE & PHARMACOTHERAPY

Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis

(2022) Ying Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fractional exhaled Nitric Oxide (FeNO) level as a predictor of COVID-19 disease severity

(2022) Yotam Lior et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Acute respiratory distress syndrome

(2022) Kristen Powers   JAAPA-Journal of the American Academy of Physician Assistants

The role of exhaled nitric oxide (FeNO) in the evaluation of lung parenchymal involvement in COVID-19 patients

(2022) Buğra Kerget et al.   Internal and Emergency Medicine

Efficacy of Covexir® ( Ferula foetida oleo‐gum) treatment in symptomatic improvement of patients with mild to moderate COVID ‐19: A randomized, double‐blind, placebo‐controlled trial

(2022) Maede Hasanpour et al.   PHYTOTHERAPY RESEARCH

Controlled therapeutic delivery of CO from carbon monoxide-releasing molecules (CORMs)

(2022) Ho-Ik Choi et al.   JOURNAL OF CONTROLLED RELEASE

Sodium hydrosulfide and bone marrow derived mesenchymal stem cells combined therapy for bleomycin induced pulmonary fibrosis in rats: Implication of micro RNA-21 and Lnc GAS5

(2022) Seham Z. Nassar et al.   LIFE SCIENCES

Inhaled Nitric Oxide for Clinical Management of COVID-19: A Systematic Review and Meta-Analysis

(2022) Jaber S. Alqahtani et al.   International Journal of Environmental Research and Public Health

The role of sulfur compounds in chronic obstructive pulmonary disease

(2022) Simin Jiang et al.   Frontiers in Molecular Biosciences

Alveolar Nitric Oxide in Chronic Obstructive Pulmonary Disease—A Two-Year Follow-Up

(2022) Marieann Högman et al.   Biomedicines

Pulmonary Arterial Hypertension: Diagnosis, Treatment, and Novel Advances

(2021) Bradley A Maron et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Highly sensitive gas sensing platforms based on field effect Transistor-A review

(2021) Pan Zhang et al.   ANALYTICA CHIMICA ACTA

Gasping for sulfide: A critical appraisal of hydrogen sulfide in lung disease and accelerated aging

(2021) Dario Pacitti et al.   ANTIOXIDANTS & REDOX SIGNALING

Clinical Efficacy of Nitric Oxide Nasal Spray (NONS) for the Treatment of Mild COVID-19 Infection

(2021) Stephen Winchester et al.   JOURNAL OF INFECTION

Endogenous SO2-dependent Smad3 redox modification controls vascular remodeling

(2021) Yaqian Huang et al.   Redox Biology

The Role of Hydrogen Sulfide in Respiratory Diseases

(2021) Saadullah Khattak et al.   Biomolecules

Rationale and Design of the Groningen Intervention Study for the Preservation of Cardiac Function with Sodium Thiosulfate after ST-segment Elevation Myocardial Infarction (GIPS-IV) Trial

(2021) Marie-Sophie L.Y. de Koning et al.   AMERICAN HEART JOURNAL

The two faces of cyanide: an environmental toxin and a potential novel mammalian gasotransmitter

(2021) Karim Zuhra et al.   FEBS Journal

Carbon Monoxide and Nitric Oxide as Examples of the Youngest Class of Transmitters

(2021) Alicja Nowaczyk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Eosinophilia and fractional exhaled nitric oxide levels in chronic obstructive lung disease

(2021) Srinadh Annangi et al.   THORAX

Relationship Between Endogenous Hydrogen Sulfide and Pulmonary Vascular Indexes on High-Resolution Computed Tomography in Patients with Chronic Obstructive Pulmonary Disease

(2021) Yi-Xuan Liao et al.   International Journal of Chronic Obstructive Pulmonary Disease

Fractional Exhaled Nitric Oxide Guided-Therapy in Chronic Obstructive Pulmonary Disease: A Stratified, Randomized, Controlled Trial

(2021) Kang-Cheng Su et al.   ARCHIVOS DE BRONCONEUMOLOGIA

Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis

(2020) Vikram Saini et al.   Nature Communications

Hydrogen Sulfide Attenuates Particulate Matter-Induced Emphysema and Airway Inflammation Through Nrf2-Dependent Manner

(2020) Guohua Jia et al.   Frontiers in Pharmacology

Chinese expert consensus-based guideline on assessment and management of asthma exacerbation

(2020) Jiangtao Lin et al.   Journal of Thoracic Disease

Nitric oxide and hydrogen sulfide: a nice pair in the respiratory system

(2020) Salvatore Fuschillo et al.   CURRENT MEDICINAL CHEMISTRY

Sulfur dioxide induces vascular relaxation through PI3K/Akt/eNOS and NO/cGMP signaling pathways in rats

(2020) Q Zhang et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

The role of nitric oxide (NO) levels in patients with obstructive sleep apnea-hypopnea syndrome: a meta-analysis

(2020) Zeng-Hong Wu et al.   Sleep and Breathing

H2S as a potential defense against COVID-19?

(2020) Guangdong Yang   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Pseudomonas aeruginosa Biofilm Eradication via Nitric Oxide-Releasing Cyclodextrins

(2020) Kaitlyn R. Rouillard et al.   ACS Infectious Diseases

Can Measurements of Inflammatory Biomarkers Be Used to Spot Respiratory Viral Infections?

(2020) Anirban Sinha et al.   Viruses-Basel

Mitigation of the replication of SARS-CoV-2 by nitric oxide in vitro

(2020) Dario Akaberi et al.   Redox Biology

Exogenous Nitric Oxide Improves Antibiotic Susceptibility in Resistant Bacteria

(2020) Kaitlyn R. Rouillard et al.   ACS Infectious Diseases

Hydrogen sulfide as a novel biomarker of asthma and chronic obstructive pulmonary disease

(2020) Yasuhito Suzuki et al.   ALLERGOLOGY INTERNATIONAL

GYY4137 attenuates LPS-induced acute lung injury via heme oxygenase-1 modulation

(2019) Lei Jiang et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Air pollution may affect the assessment of smoking habits by exhaled carbon monoxide measurements

(2019) Iwona Gregorczyk-Maga et al.   ENVIRONMENTAL RESEARCH

Exhaled carbon monoxide levels in obstructive sleep apnoea

(2019) Adrian Kis et al.   Journal of Breath Research

Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling

(2019) Patrick Coulombe et al.   Cell Reports

Antibiofilm efficacy of nitric oxide-releasing alginates against cystic fibrosis bacterial pathogens

(2019) Mona Jasmine R. Ahonen et al.   ACS Infectious Diseases

Measurement of Fractional Exhaled Nitric Oxide: Comparison of Three Different Analysers

(2019) Stephanie Korn et al.   RESPIRATION

Biological Effects of Thermal Water-Associated Hydrogen Sulfide on Human Airways and Associated Immune Cells: Implications for Respiratory Diseases

(2019) Joana Viegas et al.   Frontiers in Public Health

Management of Severe Asthma: a European Respiratory Society/American Thoracic Society Guideline

(2019) Fernando Holguin et al.   EUROPEAN RESPIRATORY JOURNAL

Exhaled Carbon Monoxide Levels in Forty Resistant to Cessation Male Smokers after Six Months of Full Switch to Electronic Cigarettes (e-Cigs) or to A Tobacco Heating Systems (THS)

(2019) Fabio Beatrice et al.   International Journal of Environmental Research and Public Health

Carbon monoxide in lung cell physiology and disease

(2018) Stefan W. Ryter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Phase II Clinical Trial of Low-Dose Inhaled Carbon Monoxide in Idiopathic Pulmonary Fibrosis

(2018) Ivan O. Rosas et al.   CHEST

Modeling Pulmonary Gas Exchange and Single-Exhalation Profiles of Carbon Monoxide

(2018) Ramin Ghorbani et al.   Frontiers in Physiology

Ambient sulfur dioxide levels associated with reduced risk of initial outpatient visits for tuberculosis: A population based time series analysis

(2017) Erjia Ge et al.   ENVIRONMENTAL POLLUTION

Primary ciliary dyskinesia ciliated airway cells show increased susceptibility to Haemophilus influenzae biofilm formation

(2017) Woolf T. Walker et al.   EUROPEAN RESPIRATORY JOURNAL

A European Respiratory Society technical standard: exhaled biomarkers in lung disease

(2017) Ildiko Horváth et al.   EUROPEAN RESPIRATORY JOURNAL

Breath analysis using external cavity diode lasers: a review

(2017) Ismail Bayrakli   JOURNAL OF BIOMEDICAL OPTICS

Complementary roles of gasotransmitters CO and H2S in sleep apnea

(2017) Ying-Jie Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broad-Range Antiviral Activity of Hydrogen Sulfide Against Highly Pathogenic RNA Viruses

(2017) Nikolay Bazhanov et al.   Scientific Reports

Neglected role of hydrogen sulfide in sulfur mustard poisoning: Keap1 S-sulfhydration and subsequent Nrf2 pathway activation

(2017) Wenqi Meng et al.   Scientific Reports

Hydrogen Sulfide Is an Antiviral and Antiinflammatory Endogenous Gasotransmitter in the Airways. Role in Respiratory Syncytial Virus Infection

(2016) Teodora Ivanciuc et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Hydrogen Sulfide Prevents and Partially Reverses Ozone-Induced Features of Lung Inflammation and Emphysema in Mice

(2016) Feng Li et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia

(2016) Jane S. Lucas et al.   EUROPEAN RESPIRATORY JOURNAL

H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea

(2016) Guoxiang Yuan et al.   Science Signaling

Second Messengers

(2016) Alexandra C. Newton et al.   Cold Spring Harbor Perspectives in Biology

Endogenous sulfur dioxide alleviates collagen remodeling via inhibiting TGF-β/Smad pathway in vascular smooth muscle cells

(2016) Yaqian Huang et al.   Scientific Reports

H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea

(2016) Guoxiang Yuan et al.   Science Signaling

Nitric Oxide Regulation of Bacterial Biofilms

(2015) Dhruv P. Arora et al.   BIOCHEMISTRY

Thiol activated prodrugs of sulfur dioxide (SO2) as MRSA inhibitors

(2015) Kundansingh A. Pardeshi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

IRG1 induced by heme oxygenase-1/carbon monoxide inhibits LPS-mediated sepsis and pro-inflammatory cytokine production

(2015) Md Jamal Uddin et al.   Cellular & Molecular Immunology

Carbon monoxide down-modulates Toll-like receptor 4/MD2 expression on innate immune cells and reduces endotoxic shock susceptibility

(2015) Sebastián A. Riquelme et al.   IMMUNOLOGY

Role of Hydrogen Sulfide in Paramyxovirus Infections

(2015) Hui Li et al.   JOURNAL OF VIROLOGY

An in vivo safety and efficacy demonstration of a topical liposomal nitric oxide donor treatment for Staphylococcus aureus biofilm–associated rhinosinusitis

(2015) Camille Jardeleza et al.   Translational Research

Systemic hydrogen sulfide administration partially restores normal alveolarization in an experimental animal model of bronchopulmonary dysplasia

(2014) Alicia Madurga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Enhanced Lung Epithelial Specification of Human Induced Pluripotent Stem Cells on Decellularized Lung Matrix

(2014) Sarah E. Gilpin et al.   ANNALS OF THORACIC SURGERY

Gasotransmitters: growing pains and joys

(2014) Rui Wang   TRENDS IN BIOCHEMICAL SCIENCES

Sulfur dioxide inhibits vascular smooth muscle cell proliferation via suppressing the Erk/MAP kinase pathway mediated by cAMP/PKA signaling

(2014) D Liu et al.   Cell Death & Disease

The Inhibitory Role of Hydrogen Sulfide in Airway Hyperresponsiveness and Inflammation in a Mouse Model of Asthma

(2013) Gensheng Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Carbon monoxide in exhaled breath testing and therapeutics

(2013) Stefan W Ryter et al.   Journal of Breath Research

The message in the air: Hydrogen sulfide metabolism in chronic respiratory diseases

(2012) Yahong Chen et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Hydrogen Sulfide Ameliorates Tobacco Smoke-Induced Oxidative Stress and Emphysema in Mice

(2011) Weihong Han et al.   ANTIOXIDANTS & REDOX SIGNALING

Design, Synthesis, and Evaluation of Thiol-Activated Sources of Sulfur Dioxide (SO2) as Antimycobacterial Agents

(2011) Satish R. Malwal et al.   JOURNAL OF MEDICINAL CHEMISTRY

Should we stay or should we go: mechanisms and ecological consequences for biofilm dispersal

(2011) Diane McDougald et al.   NATURE REVIEWS MICROBIOLOGY

Effect of the influenza A (H1N1) live attenuated intranasal vaccine on nitric oxide (FENO) and other volatiles in exhaled breath

(2011) A Mashir et al.   Journal of Breath Research

Exhaled Nitric Oxide in Pulmonary Diseases

(2010) Peter J. Barnes et al.   CHEST

Avaliação da concentração de monóxido de carbono no ar exalado em tabagistas com DPOC

(2010) Gustavo Chatkin et al.   Jornal Brasileiro de Pneumologia

Protective effect of hydrogen sulfide on hypoxic respiratory suppression in medullary slice of neonatal rats

(2010) Ji-Gang Pan et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Activation of PPAR-γ by Carbon Monoxide from CORM-2 Leads to the Inhibition of iNOS but not COX-2 Expression in LPS-Stimulated Macrophages

(2009) Konstantin Tsoyi et al.   INFLAMMATION

Effects of sulfur dioxide on hypoxic pulmonary vascular structural remodeling

(2009) Yan Sun et al.   LABORATORY INVESTIGATION

Serum hydrogen sulfide as a novel marker predicting bacterial involvement in patients with community-acquired lower respiratory tract infections

(2009) Ya-Hong CHEN et al.   RESPIROLOGY

Endogenously generated sulfur dioxide and its vasorelaxant effect in rats1

(2008) Shu-xu DU et al.   ACTA PHARMACOLOGICA SINICA

H2S-donating sildenafil (ACS6) inhibits superoxide formation and gp91phox expression in arterial endothelial cells: role of protein kinases A and G

(2008) S Muzaffar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Circulating Carbon Monoxide Level Is Elevated After Sleep in Patients With Obstructive Sleep Apnea

(2008) Masayoshi Kobayashi et al.   CHEST

Characterization of a Novel, Water-Soluble Hydrogen Sulfide–Releasing Molecule (GYY4137)

(2008) Ling Li et al.   CIRCULATION

Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma

(2008) Ya-Hong Chen et al.   CYTOKINE

Carbon monoxide–saturated preservation solution protects lung grafts from ischemia–reperfusion injury

(2008) Junichi Kohmoto et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Endogenous hydrogen sulfide is involved in regulation of respiration in medullary slice of neonatal rats

(2008) H. Hu et al.   NEUROSCIENCE

Recent developments in nitric oxide donor drugs

(2007) M R Miller et al.   BRITISH JOURNAL OF PHARMACOLOGY