Racgap1 knockdown results in cells with multiple cilia due to cytokinesis failure

Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD)

(2018) Anna S. Nikonova et al.   FASEB JOURNAL

Overexpression of Rac GTPase Activating Protein 1 Contributes to Proliferation of Cancer Cells by Reducing Hippo Signaling to Promote Cytokinesis

(2018) Xiao-Mei Yang et al.   GASTROENTEROLOGY

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

The PIDDosome activates p53 in response to supernumerary centrosomes

(2017) Luca L. Fava et al.   GENES & DEVELOPMENT

The Cilium: Cellular Antenna and Central Processing Unit

(2017) Jarema J. Malicki et al.   TRENDS IN CELL BIOLOGY

Regulation of primary cilia formation by the ubiquitin–proteasome system

(2016) Robert F. Shearer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Progressive loss of RacGAP1/ ogre activity has sequential effects on cytokinesis and zebrafish development

(2016) Rachel M. Warga et al.   DEVELOPMENTAL BIOLOGY

RacGAP1 expression, increasing tumor malignant potential, as a predictive biomarker for lymph node metastasis and poor prognosis in colorectal cancer

(2015) Hiroki Imaoka et al.   CARCINOGENESIS

Ionizing radiation increases primary cilia incidence and induces multiciliation in C2C12 myoblasts

(2015) Alžběta Filipová et al.   CELL BIOLOGY INTERNATIONAL

An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes

(2015) Gabrielle Wheway et al.   NATURE CELL BIOLOGY

Cilia in the choroid plexus: their roles in hydrocephalus and beyond

(2015) Keishi Narita et al.   Frontiers in Cellular Neuroscience

Photoreceptor Sensory Cilium: Traversing the Ciliary Gate

(2015) Hemant Khanna   Cells

Centralspindlin assembly and 2 phosphorylations on MgcRacGAP by Polo-like kinase 1 initiate Ect2 binding in early cytokinesis

(2014) Hyunjung Kim et al.   CELL CYCLE

Clinical significance of RacGAP1 expression at the invasive front of gastric cancer

(2014) Susumu Saigusa et al.   Gastric Cancer

Causes and consequences of centrosome abnormalities in cancer

(2014) S. A. Godinho et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Presence of primary cilia in cancer cells correlates with prognosis of pancreatic ductal adenocarcinoma

(2013) Katsura Emoto et al.   HUMAN PATHOLOGY

Centralspindlin — the missing link

(2013) Kim Baumann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Centrosome amplification in tumorigenesis

(2012) Simon J. Anderhub et al.   CANCER LETTERS

C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis

(2012) Pauline C. Conroy et al.   CELL CYCLE

Supernumerary Centrosomes Nucleate Extra Cilia and Compromise Primary Cilium Signaling

(2012) Moe R. Mahjoub et al.   CURRENT BIOLOGY

A Clinical Overview of Centrosome Amplification in Human Cancers

(2012) Jason Yongsheng Chan   International Journal of Biological Sciences

Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis

(2012) Sergey Lekomtsev et al.   NATURE

Proteomic analysis of multiple primary cilia reveals a novel mode of ciliary development in mammals

(2012) K. Narita et al.   Biology Open

Aurora B and 14-3-3 Coordinately Regulate Clustering of Centralspindlin during Cytokinesis

(2010) Max E. Douglas et al.   CURRENT BIOLOGY

The primary cilium at a glance

(2010) P. Satir et al.   JOURNAL OF CELL SCIENCE

Functional genomic screen for modulators of ciliogenesis and cilium length

(2010) Joon Kim et al.   NATURE

Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3

(2009) Rachaneekorn Tammachote et al.   HUMAN MOLECULAR GENETICS

Dual and opposing roles of primary cilia in medulloblastoma development

(2009) Young-Goo Han et al.   NATURE MEDICINE

Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis

(2009) Sunny Y Wong et al.   NATURE MEDICINE

Loss of polycystin-1 causes centrosome amplification and genomic instability

(2008) Lorenzo Battini et al.   HUMAN MOLECULAR GENETICS

Regulation of cytokinesis by Rho GTPase flux

(2008) Ann L. Miller et al.   NATURE CELL BIOLOGY

STRING 8--a global view on proteins and their functional interactions in 630 organisms

(2008) L. J. Jensen et al.   NUCLEIC ACIDS RESEARCH