Exploring New Inflammatory Biomarkers and Pathways during LPS-Induced M1 Polarization

Dipeptidyl Vinyl Sulfone as a Novel Chemical Tool to Inhibit HMGB1/NLRP3-Inflammasome and Inflamma-miRs in Aβ-Mediated Microglial Inflammation

(2016) Ana S. Falcão et al.   ACS Chemical Neuroscience

Brain Endothelial miR-146a Negatively Modulates T-Cell Adhesion through Repressing Multiple Targets to Inhibit NF-κB Activation

(2015) Dongsheng Wu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inflammasome-Induced IL-1  Secretion in Microglia Is Characterized by Delayed Kinetics and Is Only Partially Dependent on Inflammatory Caspases

(2015) S. M. Burm et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

(2015) Dora Brites et al.   Frontiers in Cellular Neuroscience

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

(2015) Margaret Alexander et al.   Nature Communications

NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes

(2015) Audrey Gustin et al.   PLoS One

Nitric oxide/cyclic GMP signaling regulates motility of a microglial cell line and primary microglia in vitro

(2014) Hannah Scheiblich et al.   BRAIN RESEARCH

Microglia and inflammation: conspiracy, controversy or control?

(2014) Adelaide Fernandes et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells

(2014) Ruozhou Tom Liu et al.   EXPERIMENTAL EYE RESEARCH

TGFβ1 increases microglia-mediated engulfment of apoptotic cells via upregulation of the milk fat globule-EGF factor 8

(2014) Björn Spittau et al.   GLIA

Decreased Expression of the Fractalkine Receptor CX3CR1 on Circulating Monocytes as New Feature of Sepsis-Induced Immunosuppression

(2014) Alexandre Pachot et al.   JOURNAL OF IMMUNOLOGY

Milk Fat Globule Epidermal Growth Factor-Factor VIII Is Down-Regulated in Sepsis via the Lipopolysaccharide-CD14 Pathway

(2014) H. Komura et al.   JOURNAL OF IMMUNOLOGY

Microglia display modest phagocytic capacity for extracellular tau oligomers

(2014) Petra Majerova et al.   Journal of Neuroinflammation

Mesenchymal stem cells exert anti-proliferative effect on lipopolysaccharide-stimulated BV2 microglia by reducing tumour necrosis factor-α levels

(2014) Shinsmon Jose et al.   Journal of Neuroinflammation

Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury

(2014) Hai-tao Zhu et al.   Journal of Neuroinflammation

Exosomes as a Nanodelivery System: a Key to the Future of Neuromedicine?

(2014) Arian Aryani et al.   MOLECULAR NEUROBIOLOGY

Inflammasomes in the CNS

(2014) John G. Walsh et al.   NATURE REVIEWS NEUROSCIENCE

TLR2 signaling directs NO-dependent MMP-9 induction in mouse microglia

(2014) Yanyan Bai et al.   NEUROSCIENCE LETTERS

Microglia centered pathogenesis in ALS: insights in cell interconnectivity

(2014) Dora Brites et al.   Frontiers in Cellular Neuroscience

Microglia change from a reactive to an age-like phenotype with the time in culture

(2014) Cláudia Caldeira et al.   Frontiers in Cellular Neuroscience

MicroRNAs: New Regulators of Toll-Like Receptor Signalling Pathways

(2014) Xiaobing He et al.   Biomed Research International

Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke

(2013) Ting Li et al.   BRAIN

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

(2013) Vibol Chhor et al.   BRAIN BEHAVIOR AND IMMUNITY

Involvement of MicroRNA in Microglia-Mediated Immune Response

(2013) J. Guedes et al.   Clinical & Developmental Immunology

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

(2013) Ravid Shechter et al.   IMMUNITY

The microglial activation state regulates migration and roles of matrix-dissolving enzymes for invasion

(2013) Starlee Lively et al.   Journal of Neuroinflammation

MicroRNAs as Novel Regulators of Neuroinflammation

(2013) Dominika Justyna Ksiazek-Winiarek et al.   MEDIATORS OF INFLAMMATION

Essential Role of MFG-E8 for Phagocytic Properties of Microglial Cells

(2013) Yong Liu et al.   PLoS One

IL-4/IL-13-Dependent and Independent Expression of miR-124 and Its Contribution to M2 Phenotype of Monocytic Cells in Normal Conditions and during Allergic Inflammation

(2013) Tatyana Veremeyko et al.   PLoS One

Integrated Expression Profiles of mRNA and miRNA in Polarized Primary Murine Microglia

(2013) Robert W. Freilich et al.   PLoS One

Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage

(2013) G. K. Sheridan et al.   Open Biology

Regulation of HMGB1 release by inflammasomes

(2013) Ben Lu et al.   Protein & Cell

N9 microglial cells polarized by LPS and IL4 show differential responses to secondary environmental stimuli

(2012) Hong-Cui Liu et al.   CELLULAR IMMUNOLOGY

Microglial activation of the NLRP3 inflammasome by the priming signals derived from macrophages infected with mycobacteria

(2012) Hye-Mi Lee et al.   GLIA

Comparison of polarization properties of human adult microglia and blood-derived macrophages

(2012) Bryce A. Durafourt et al.   GLIA

MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS

(2012) Eugene D. Ponomarev et al.   GLIA

LPS-induced iNOS expression in N9 microglial cells is suppressed by geniposide via ERK, p38 and nuclear factor-κB signaling pathways

(2012) GU ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

MicroRNA-124 as a novel treatment for persistent hyperalgesia

(2012) Hanneke LDM Willemen et al.   Journal of Neuroinflammation

MFG-E8 Mediates Primary Phagocytosis of Viable Neurons during Neuroinflammation

(2012) M. Fricker et al.   JOURNAL OF NEUROSCIENCE

Lipopolysaccharide-Induced Microglial Activation and Neuroprotection against Experimental Brain Injury Is Independent of Hematogenous TLR4

(2012) Z. Chen et al.   JOURNAL OF NEUROSCIENCE

Unconjugated Bilirubin Restricts Oligodendrocyte Differentiation and Axonal Myelination

(2012) Andreia Barateiro et al.   MOLECULAR NEUROBIOLOGY

ER Stress, Mitochondrial Dysfunction and Calpain/JNK Activation are Involved in Oligodendrocyte Precursor Cell Death by Unconjugated Bilirubin

(2012) Andreia Barateiro et al.   NEUROMOLECULAR MEDICINE

MicroRNA 146a (miR-146a) Is Over-Expressed during Prion Disease and Modulates the Innate Immune Response and the Microglial Activation State

(2012) Reuben Saba et al.   PLoS One

Dysregulated expression of miR-146a contributes to age-related dysfunction of macrophages

(2011) Minghong Jiang et al.   AGING CELL

Dynamic motility of microglia: Purinergic modulation of microglial movement in the normal and pathological brain

(2011) Keiko Ohsawa et al.   GLIA

miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production

(2011) Ana L. Cardoso et al.   IMMUNOLOGY

A trio of microRNAs that control Toll-like receptor signalling

(2011) S. R. Quinn et al.   INTERNATIONAL IMMUNOLOGY

Sildenafil attenuates LPS-induced pro-inflammatory responses through down-regulation of intracellular ROS-related MAPK/NF-κB signaling pathways in N9 microglia

(2011) Siqi Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dynamics of neuron-glia interplay upon exposure to unconjugated bilirubin

(2011) Sandra L. Silva et al.   JOURNAL OF NEUROCHEMISTRY

Inflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microglia

(2011) Richa Hanamsagar et al.   JOURNAL OF NEUROCHEMISTRY

HMGB1 Acts on Microglia Mac1 to Mediate Chronic Neuroinflammation That Drives Progressive Neurodegeneration

(2011) H.-M. Gao et al.   JOURNAL OF NEUROSCIENCE

LPS Induces HMGB1 Relocation and Release by Activating the NF-κB-CBP Signal Transduction Pathway in the Murine Macrophage-Like Cell Line RAW264.7

(2011) Chuan-Xin Wu et al.   JOURNAL OF SURGICAL RESEARCH

Outbred ICR/CD1 mice display more severe neuroinflammation mediated by microglial TLR4/CD14 activation than inbred C57Bl/6 mice

(2011) M. Nikodemova et al.   NEUROSCIENCE

Inhibitory mechanism of MMP-9 gene expression by ethyl pyruvate in lipopolysaccharide-stimulated BV2 microglial cells

(2011) Eun-Jung Lee et al.   NEUROSCIENCE LETTERS

Resveratrol differentially modulates inflammatory responses of microglia and astrocytes

(2010) Xiaofeng Lu et al.   Journal of Neuroinflammation

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

(2010) Eugene D Ponomarev et al.   NATURE MEDICINE

Features of bilirubin-induced reactive microglia: From phagocytosis to inflammation

(2010) Sandra L. Silva et al.   NEUROBIOLOGY OF DISEASE

Export of microRNAs and microRNA-protective protein by mammalian cells

(2010) Kai Wang et al.   NUCLEIC ACIDS RESEARCH

Microglia: biology and pathology

(2009) Manuel B. Graeber et al.   ACTA NEUROPATHOLOGICA

Matrix metalloproteinases: Evolution, gene regulation and functional analysis in mouse models

(2009) Miriam Fanjul-Fernández et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

miR-146a Is Critical for Endotoxin-induced Tolerance

(2009) Md A. Nahid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Adenosine A2A receptor mediates microglial process retraction

(2009) Anna G Orr et al.   NATURE NEUROSCIENCE

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

Microglial clearance function in health and disease

(2008) I. Napoli et al.   NEUROSCIENCE

Induction and subcellular localization of high-mobility group box–1 (HMGB1) in the postischemic rat brain

(2007) Jung-Bin Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH