MicroRNA 146a (miR-146a) Is Over-Expressed during Prion Disease and Modulates the Innate Immune Response and the Microglial Activation State

The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

(2016) Anja Henn   ALTEX-Alternatives to Animal Experimentation

Rapid Changes in MicroRNA-146a Expression Negatively Regulate the IL-1 -Induced Inflammatory Response in Human Lung Alveolar Epithelial Cells

(2014) M. M. Perry et al.   JOURNAL OF IMMUNOLOGY

MyD88-adaptor protein acts as a preventive mechanism for memory deficits in a mouse model of Alzheimer's disease

(2011) Jean-Philippe Michaud et al.   Molecular Neurodegeneration

miR-221 suppresses ICAM-1 translation and regulates interferon-γ-induced ICAM-1 expression in human cholangiocytes

(2010) Guoku Hu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrPSc, even upon LPS stimulation

(2010) Martina M. Hughes et al.   GLIA

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Increased expression of miRNA-146a in Alzheimer's disease transgenic mouse models

(2010) Y.Y. Li et al.   NEUROSCIENCE LETTERS

MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47

(2009) Andreas Junker et al.   BRAIN

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

miR-146a Is Critical for Endotoxin-induced Tolerance

(2009) Md A. Nahid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2

(2009) J. Hou et al.   JOURNAL OF IMMUNOLOGY

Characterization of an NF-κB-regulated, miRNA-146a-mediated down-regulation of complement factor H (CFH) in metal-sulfate-stressed human brain cells

(2009) Aileen I. Pogue et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling

(2009) James M. Hill et al.   NEUROREPORT

miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses

(2009) G. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression

(2009) J. T. Zipprich et al.   RNA

Systemic Inflammation Induces Acute Behavioral and Cognitive Changes and Accelerates Neurodegenerative Disease

(2008) Colm Cunningham et al.   BIOLOGICAL PSYCHIATRY

An NF-κB-sensitive Micro RNA-146a-mediated Inflammatory Circuit in Alzheimer Disease and in Stressed Human Brain Cells

(2008) Walter J. Lukiw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll-Like Receptor 2 Acts as a Natural Innate Immune Receptor to Clear Amyloid  1-42 and Delay the Cognitive Decline in a Mouse Model of Alzheimer's Disease

(2008) K. L. Richard et al.   JOURNAL OF NEUROSCIENCE

Accelerated Prion Disease Pathogenesis in Toll-Like Receptor 4 Signaling-Mutant Mice

(2008) D. S. Spinner et al.   JOURNAL OF VIROLOGY

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

A miRNA Signature of Prion Induced Neurodegeneration

(2008) Reuben Saba et al.   PLoS One

MicroRNA miR-146a and further oncogenesis-related cellular microRNAs are dysregulated in HTLV-1-transformed T lymphocytes

(2008) Klemens Pichler et al.   Retrovirology

Screening of innate immune receptors in neurodegenerative diseases: A similar pattern

(2007) Maryse Letiembre et al.   NEUROBIOLOGY OF AGING