Balancing Inflammation: The Link between Th17 and Regulatory T Cells

Hyperlipidemia Promotes Anti-Donor Th17 Responses That Accelerate Allograft Rejection

(2015) J. Yuan et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The role of nuclear receptors in regulation of Th17/Treg biology and its implications for diseases

(2015) Benjamin V. Park et al.   Cellular & Molecular Immunology

Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation

(2015) Nicola Gagliani et al.   NATURE

Development of a unique epigenetic signature during in vivo Th17 differentiation

(2015) Bi-Huei Yang et al.   NUCLEIC ACIDS RESEARCH

Functional and Phenotypic Plasticity of CD4+T Cell Subsets

(2015) Tiffany Caza et al.   Biomed Research International

The effect of mammalian target of rapamycin inhibition on T helper type 17 and regulatory T cell differentiationin vitroandin vivoin kidney transplant recipients

(2014) Kyoung Woon Kim et al.   IMMUNOLOGY

Cutting Edge: Foxp3+CD4+CD25+ Regulatory T Cells Induced by IL-2 and TGF-  Are Resistant to Th17 Conversion by IL-6

(2014) S. G. Zheng et al.   JOURNAL OF IMMUNOLOGY

Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210

(2014) Haopeng Wang et al.   NATURE IMMUNOLOGY

Th17 Cells in Cancer: The Ultimate Identity Crisis

(2014) Stefanie R. Bailey et al.   Frontiers in Immunology

Metabolic control of the Treg/Th17 axis

(2013) Joseph Barbi et al.   IMMUNOLOGICAL REVIEWS

Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways

(2013) Jiyeon S Kim et al.   NATURE IMMUNOLOGY

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

(2013) Noriko Komatsu et al.   NATURE MEDICINE

mTOR and metabolic pathways in T cell quiescence and functional activation

(2013) Kai Yang et al.   SEMINARS IN IMMUNOLOGY

Regulation of Immune Responses by mTOR

(2012) Jonathan D. Powell et al.   Annual Review of Immunology

CD4+T Cells: Differentiation and Functions

(2012) Rishi Vishal Luckheeram et al.   Clinical & Developmental Immunology

Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

(2012) Takahisa Miyao et al.   IMMUNITY

Metabolic reprogramming and metabolic dependency in T cells

(2012) Ruoning Wang et al.   IMMUNOLOGICAL REVIEWS

mTOR, metabolism, and the regulation of T-cell differentiation and function

(2012) Adam T. Waickman et al.   IMMUNOLOGICAL REVIEWS

IL-17 Mediated Inflammation Promotes Tumor Growth and Progression in the Skin

(2012) Donggou He et al.   PLoS One

Controversies on the role of Th17 in cancer: a TGF-β-dependent immunosuppressive activity?

(2012) François Martin et al.   TRENDS IN MOLECULAR MEDICINE

PI3K-Akt-mTORC1-S6K1/2 Axis Controls Th17 Differentiation by Regulating Gfi1 Expression and Nuclear Translocation of RORγ

(2012) Yutaka Kurebayashi et al.   Cell Reports

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

(2011) Eric V. Dang et al.   CELL

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Th1 and Th17 Cells Exhibit Epigenetic Stability at Signature Cytokine and Transcription Factor Loci

(2011) C. J. Cohen et al.   JOURNAL OF IMMUNOLOGY

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

(2011) Greg M Delgoffe et al.   NATURE IMMUNOLOGY

The Th17/Treg imbalance and cytokine environment in peripheral blood of patients with rheumatoid arthritis

(2011) Wenhong Wang et al.   RHEUMATOLOGY INTERNATIONAL

Th17: Contributors to Allograft Rejection and a Barrier to the Induction of Transplantation Tolerance?

(2011) Radhika Chadha et al.   TRANSPLANTATION

The impact of Th17 cells on transplant rejection and the induction of tolerance

(2010) Sebastiaan Heidt et al.   Current Opinion in Organ Transplantation

Stability of the Regulatory T Cell Lineage in Vivo

(2010) Y. P. Rubtsov et al.   SCIENCE

Th17 Cells and Transplant Acceptance

(2010) Bryna E. Burrell et al.   TRANSPLANTATION

IL-1β and IL-2 convert human Treg into TH17 cells

(2009) Florence Deknuydt et al.   CLINICAL IMMUNOLOGY

Developmental plasticity of Th17 and Treg cells

(2009) Yun Kyung Lee et al.   CURRENT OPINION IN IMMUNOLOGY

Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

(2009) Gang Wei et al.   IMMUNITY

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

Identification of IL-17-producing FOXP3+ regulatory T cells in humans

(2009) K. S. Voo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-specific Th17-polarized cells eradicate large established melanoma

(2008) P. Muranski et al.   BLOOD

De novo induction of antigen-specific CD4+CD25+Foxp3+ regulatory T cells in vivo following systemic antigen administration accompanied by blockade of mTOR

(2008) Johnthomas Kang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

(2008) Liang Zhou et al.   NATURE

IL-21 and TGF-β are required for differentiation of human TH17 cells

(2008) Li Yang et al.   NATURE

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells

(2008) A. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin 17–producing T helper cells in alloimmunity

(2008) Fleur Samantha Benghiat et al.   Transplantation Reviews