The role of mucosal barriers in disease progression and transmission

Modeling insights into SARS-CoV-2 respiratory tract infections prior to immune protection

(2022) Alexander Chen et al.   BIOPHYSICAL JOURNAL

Stability of respiratory-like droplets under evaporation

(2022) Carola Seyfert et al.   Physical Review Fluids

Aerosol Transport Modeling: The Key Link Between Lung Infections of Individuals and Populations

(2022) Chantal Darquenne et al.   Frontiers in Physiology

Cytokine Storm and Mucus Hypersecretion in COVID-19: Review of Mechanisms

(2021) Mohsin Ali Khan et al.   Journal of Inflammation Research

Structural Alterations of Mucins Are Associated with Losses in Functionality

(2021) Matthias Marczynski et al.   BIOMACROMOLECULES

N-Glycolylneuraminic Acid in Animal Models for Human Influenza A Virus

(2021) Cindy M. Spruit et al.   Viruses-Basel

Mechanistic theory predicts the effects of temperature and humidity on inactivation of SARS-CoV-2 and other enveloped viruses

(2021) Dylan H Morris et al.   eLife

Mucus

(2021) Abigail McShane et al.   CURRENT BIOLOGY

Water evaporation from solute-containing aerosol droplets: Effects of internal concentration and diffusivity profiles and onset of crust formation

(2021) Majid Rezaei et al.   PHYSICS OF FLUIDS

Precipitation dynamics of surrogate respiratory sessile droplets leading to possible fomites

(2021) Abdur Rasheed et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Fibrinogen Gamma Chain Promotes Aggregation of Vesicular Stomatitis Virus in Saliva

(2020) Valesca Anschau et al.   Viruses-Basel

Microarray Strategies for Exploring Bacterial Surface Glycans and Their Interactions With Glycan-Binding Proteins

(2020) María Asunción Campanero-Rhodes et al.   Frontiers in Microbiology

A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract

(2020) Christian Quirouette et al.   PLoS Computational Biology

Surface Chemistry Can Unlock Drivers of Surface Stability of SARS-CoV-2 in Variety of Environmental Conditions

(2020) Edris Joonaki et al.   Chem

Physics of virus transmission by speaking droplets

(2020) Roland R. Netz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Speech can produce jet-like transport relevant to asymptomatic spreading of virus

(2020) Manouk Abkarian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Survival of MS2 and Φ6 viruses in droplets as a function of relative humidity, pH, and salt, protein, and surfactant concentrations

(2020) Kaisen Lin et al.   PLoS One

The evolution of collective infectious units in viruses

(2019) Asher Leeks et al.   VIRUS RESEARCH

Human saliva and model saliva at bulk to adsorbed phases – similarities and differences

(2019) Anwesha Sarkar et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Mucin glycans attenuate the virulence of Pseudomonas aeruginosa in infection

(2019) Kelsey M. Wheeler et al.   Nature Microbiology

The biology of mucus: Composition, synthesis and organization

(2018) Rama Bansil et al.   ADVANCED DRUG DELIVERY REVIEWS

Technological strategies to estimate and control diffusive passage times through the mucus barrier in mucosal drug delivery

(2018) Jay M. Newby et al.   ADVANCED DRUG DELIVERY REVIEWS

Engineering the Mucus Barrier

(2018) T.L. Carlson et al.   Annual Review of Biomedical Engineering

Selective permeability of mucus barriers

(2018) Jacob Witten et al.   CURRENT OPINION IN BIOTECHNOLOGY

Physico-chemical characteristics of evaporating respiratory fluid droplets

(2018) Eric P. Vejerano et al.   Journal of the Royal Society Interface

New insights into the mechanisms controlling the bronchial mucus balance

(2018) Cyril Karamaoun et al.   PLoS One

Aerosol microdroplets exhibit a stable pH gradient

(2018) Haoran Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electrostatic Variation of Haemagglutinin as a Hallmark of the Evolution of Avian Influenza Viruses

(2018) Alireza Heidari et al.   Scientific Reports

Acute Exposure to Commonly Ingested Emulsifiers Alters Intestinal Mucus Structure and Transport Properties

(2018) Jaclyn Y. Lock et al.   Scientific Reports

Survival of the Enveloped Virus Phi6 in Droplets as a Function of Relative Humidity, Absolute Humidity, and Temperature

(2018) Aaron J. Prussin et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Mucins and Their Role in Shaping the Functions of Mucus Barriers

(2018) C.E. Wagner et al.   Annual Review of Cell and Developmental Biology

Respiratory Viral Infection-Induced Microbiome Alterations and Secondary Bacterial Pneumonia

(2018) Shigeo Hanada et al.   Frontiers in Immunology

Mucins trigger dispersal of Pseudomonas aeruginosa biofilms

(2018) Julia Y. Co et al.   npj Biofilms and Microbiomes

Physicochemical properties of mucus and their impact on transmucosal drug delivery

(2017) Jasmim Leal et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Age-dependent capillary thinning dynamics of physically-associated salivary mucin networks

(2017) Caroline E. Wagner et al.   JOURNAL OF RHEOLOGY

The particle in the spider's web: transport through biological hydrogels

(2017) Jacob Witten et al.   Nanoscale

Mucus and Mucins: do they have a role in the inhibition of the human immunodeficiency virus?

(2017) Anwar Suleman Mall et al.   Virology Journal

A blueprint for robust crosslinking of mobile species in biogels with weakly adhesive molecular anchors

(2017) Jay Newby et al.   Nature Communications

Mucin Coatings Prevent Tissue Damage at the Cornea-Contact Lens Interface

(2017) Benjamin Winkeljann et al.   Advanced Materials Interfaces

Size-Limited Penetration of Nanoparticles into Porcine Respiratory Mucus after Aerosol Deposition

(2016) Xabier Murgia et al.   BIOMACROMOLECULES

The Interaction between Respiratory Pathogens and Mucus

(2016) Mark Zanin et al.   Cell Host & Microbe

Variation in pH of Model Secondary Organic Aerosol during Liquid–Liquid Phase Separation

(2016) Magda A. Dallemagne et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Direct Measurement of pH in Individual Particles via Raman Microspectroscopy and Variation in Acidity with Relative Humidity

(2016) Joel D. Rindelaub et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Interaction of porcine gastric mucin with various polycations and its influence on the boundary lubrication properties

(2016) Nikolaos Nikogeorgos et al.   POLYMER

Nanoparticles decorated with proteolytic enzymes, a promising strategy to overcome the mucus barrier

(2015) Irene Pereira de Sousa et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Dynamic responses in small intestinal mucus: Relevance for the maintenance of an intact barrier

(2015) Catherine Taylor Nordgård et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Size selectivity of intestinal mucus to diffusing particulates is dependent on surface chemistry and exposure to lipids

(2015) Hasan M. Yildiz et al.   JOURNAL OF DRUG TARGETING

Survival of Enveloped and Non-Enveloped Viruses on Inanimate Surfaces

(2015) Swan Firquet et al.   MICROBES AND ENVIRONMENTS

Using Computational Modeling To Optimize the Design of Antibodies That Trap Viruses in Mucus

(2015) Timothy Wessler et al.   ACS Infectious Diseases

Salivary Mucins Protect Surfaces from Colonization by Cariogenic Bacteria

(2014) Erica Shapiro Frenkel et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Transient Antibody-Mucin Interactions Produce a Dynamic Molecular Shield against Viral Invasion

(2014) Alex Chen et al.   BIOPHYSICAL JOURNAL

Violent expiratory events: on coughing and sneezing

(2014) Lydia Bourouiba et al.   JOURNAL OF FLUID MECHANICS

Variations in pH Sensitivity, Acid Stability, and Fusogenicity of Three Influenza Virus H3 Subtypes

(2014) Deirdre A. Costello et al.   JOURNAL OF VIROLOGY

Modeling Neutralization Kinetics of HIV by Broadly Neutralizing Monoclonal Antibodies in Genital Secretions Coating the Cervicovaginal Mucosa

(2014) Scott A. McKinley et al.   PLoS One

Respiratory Syncytial Virus Can Infect Basal Cells and Alter Human Airway Epithelial Differentiation

(2014) B. David Persson et al.   PLoS One

A Beneficiary Role for Neuraminidase in Influenza Virus Penetration through the Respiratory Mucus

(2014) Xiaoyun Yang et al.   PLoS One

Mucins Suppress Virulence Traits of Candida albicans

(2014) Nicole L. Kavanaugh et al.   mBio

Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution

(2013) Jessica M. Holmén Larsson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Spatial Configuration and Composition of Charge Modulates Transport into a Mucin Hydrogel Barrier

(2013) Leon D. Li et al.   BIOPHYSICAL JOURNAL

Particle tracking microrheology of purified gastrointestinal mucins

(2013) Pantelis Georgiades et al.   BIOPOLYMERS

High Humidity Leads to Loss of Infectious Influenza Virus from Simulated Coughs

(2013) John D. Noti et al.   PLoS One

Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase

(2013) Miriam Cohen et al.   Virology Journal

Structure and Function of the Mucus Clearance System of the Lung

(2013) B. M. Button et al.   Cold Spring Harbor Perspectives in Medicine

The Influence of Mucus Microstructure and Rheology in Helicobacter pylori Infection

(2013) Rama Bansil et al.   Frontiers in Immunology

Mechanisms by Which Ambient Humidity May Affect Viruses in Aerosols

(2012) Wan Yang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Mucin Biopolymers As Broad-Spectrum Antiviral Agents

(2012) Oliver Lieleg et al.   BIOMACROMOLECULES

α2-3- and α2-6- N-linked sialic acids allow efficient interaction of Newcastle Disease Virus with target cells

(2012) Lorena Sánchez-Felipe et al.   GLYCOCONJUGATE JOURNAL

A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

(2012) B. Button et al.   SCIENCE

Cell Receptors for Influenza a Viruses and the Innate Immune Response

(2012) Irene Ramos et al.   Frontiers in Microbiology

Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated withN-acetyl cysteine

(2011) Jung Soo Suk et al.   Nanomedicine

Dynamics of Airborne Influenza A Viruses Indoors and Dependence on Humidity

(2011) Wan Yang et al.   PLoS One

Biological hydrogels as selective diffusion barriers

(2011) Oliver Lieleg et al.   TRENDS IN CELL BIOLOGY

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Helicobacter pylori moves through mucus by reducing mucin viscoelasticity

(2009) J. P. Celli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MUC1 Limits Helicobacter pylori Infection both by Steric Hindrance and by Acting as a Releasable Decoy

(2009) Sara K. Lindén et al.   PLoS Pathogens

Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

(2008) Samuel K. Lai et al.   ADVANCED DRUG DELIVERY REVIEWS

Barrier properties of mucus

(2008) Richard A. Cone   ADVANCED DRUG DELIVERY REVIEWS

Mucins in the mucosal barrier to infection

(2008) S K Linden et al.   Mucosal Immunology

Multiple components contribute to ability of saliva to inhibit influenza viruses

(2008) M. R. White et al.   Oral microbiology and immunology

Structure and Function of the Polymeric Mucins in Airways Mucus

(2007) David J. Thornton et al.   Annual Review of Physiology

Effect of pH on the association behavior in aqueous solutions of pig gastric mucin

(2007) Atoosa Maleki et al.   CARBOHYDRATE RESEARCH