A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract

Sequential infection experiments for quantifying innate and adaptive immunity during influenza infection

(2019) Ada W. C. Yan et al.   PLoS Computational Biology

Social evolution of innate immunity evasion in a virus

(2019) Pilar Domingo-Calap et al.   Nature Microbiology

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses

(2019) Ting Wu et al.   Nature Communications

Principles of Effective and Robust Innate Immune Response to Viral Infections: A Multiplex Network Analysis

(2019) Yufan Huang et al.   Frontiers in Immunology

Causes and Consequences of Spatial Within-Host Viral Spread

(2018) Molly Gallagher et al.   Viruses-Basel

Modelling the emergence of influenza drug resistance: The roles of surface proteins, the immune response and antiviral mechanisms

(2017) Hana M. Dobrovolny et al.   PLoS One

The Mechanisms for Within-Host Influenza Virus Control Affect Model-Based Assessment and Prediction of Antiviral Treatment

(2017) Pengxing Cao et al.   Viruses-Basel

The in vivo efficacy of neuraminidase inhibitors cannot be determined from the decay rates of influenza viral titers observed in treated patients

(2017) John Palmer et al.   Scientific Reports

Exploring virus release as a bottleneck for the spread of influenza A virus infection in vitro and the implications for antiviral therapy with neuraminidase inhibitors

(2017) Laura E. Liao et al.   PLoS One

Randomized controlled trials for influenza drugs and vaccines: a review of controlled human infection studies

(2016) Shobana Balasingam et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Cilia and Mucociliary Clearance

(2016) Ximena M. Bustamante-Marin et al.   Cold Spring Harbor Perspectives in Biology

Avian influenza viruses that cause highly virulent infections in humans exhibit distinct replicative properties in contrast to human H1N1 viruses

(2016) Philippe F. Simon et al.   Scientific Reports

Modeling Influenza Virus Infection: A Roadmap for Influenza Research

(2015) Alessandro Boianelli et al.   Viruses-Basel

Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8+ T cells

(2015) Zhongfang Wang et al.   Nature Communications

Innate Immunity and the Inter-exposure Interval Determine the Dynamics of Secondary Influenza Virus Infection and Explain Observed Viral Hierarchies

(2015) Pengxing Cao et al.   PLoS Computational Biology

Determining drug efficacy parameters for mathematical models of influenza

(2015) Noah F. Beggs et al.   Journal of Biological Dynamics

Impact of the H275Y and I223V Mutations in the Neuraminidase of the 2009 Pandemic Influenza Virus In Vitro and Evaluating Experimental Reproducibility

(2015) Eric G. Paradis et al.   PLoS One

Mechanisms of Cilia-Driven Transport in the Airways in the Absence of Mucus

(2014) Saskia Bermbach et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Routes of influenza transmission

(2013) Ben Killingley et al.   Influenza and Other Respiratory Viruses

Highly Sensitive Real-Time In Vivo Imaging of an Influenza Reporter Virus Reveals Dynamics of Replication and Spread

(2013) V. Tran et al.   JOURNAL OF VIROLOGY

Assessing Mathematical Models of Influenza Infections Using Features of the Immune Response

(2013) Hana M. Dobrovolny et al.   PLoS One

Reducing Uncertainty in Within-Host Parameter Estimates of Influenza Infection by Measuring Both Infectious and Total Viral Load

(2013) Stephen M. Petrie et al.   PLoS One

Cilia-driven particle and fluid transport over mucus-free mice tracheae

(2012) J. Hussong et al.   JOURNAL OF BIOMECHANICS

Combination Antiviral Therapy for Influenza: Predictions From Modeling of Human Infections

(2012) Alan S. Perelson et al.   JOURNAL OF INFECTIOUS DISEASES

The H275Y Neuraminidase Mutation of the Pandemic A/H1N1 Influenza Virus Lengthens the Eclipse Phase and Reduces Viral Output of Infected Cells, Potentially Compromising Fitness in Ferrets

(2012) L. T. Pinilla et al.   JOURNAL OF VIROLOGY

Linking Influenza Virus Tissue Tropism to Population-Level Reproductive Fitness

(2012) Leslie A. Reperant et al.   PLoS One

Design considerations in buildingin silicoequivalents of common experimental influenza virus assays

(2011) Benjamin P. Holder et al.   AUTOIMMUNITY

Exploring the effect of biological delays in kinetic models of influenza within a host or cell culture

(2011) Benjamin P Holder et al.   BMC PUBLIC HEALTH

Influence of particle size on regional lung deposition – What evidence is there?

(2011) Thiago C. Carvalho et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Epithelial repair mechanisms in the lung

(2010) Lynn M. Crosby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Neuraminidase inhibitors for treatment of human and avian strain influenza: A comparative modeling study

(2010) Hana M. Dobrovolny et al.   JOURNAL OF THEORETICAL BIOLOGY

Higher Level of Replication Efficiency of 2009 (H1N1) Pandemic Influenza Virus than Those of Seasonal and Avian Strains: Kinetics from Epithelial Cell Culture and Computational Modeling

(2010) H. Mitchell et al.   JOURNAL OF VIROLOGY

Quantifying the Early Immune Response and Adaptive Immune Response Kinetics in Mice Infected with Influenza A Virus

(2010) H. Miao et al.   JOURNAL OF VIROLOGY

Dynamics of Influenza Virus Infection and Pathology

(2010) R. A. Saenz et al.   JOURNAL OF VIROLOGY

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exploring Cell Tropism as a Possible Contributor to Influenza Infection Severity

(2010) Hana M. Dobrovolny et al.   PLoS One

Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus

(2010) B. Manicassamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards a quantitative understanding of the within-host dynamics of influenza A infections

(2009) A. Handel et al.   Journal of the Royal Society Interface

Simulation and Prediction of the Adaptive Immune Response to Influenza A Virus Infection

(2009) H. Y. Lee et al.   JOURNAL OF VIROLOGY

Basal cells as stem cells of the mouse trachea and human airway epithelium

(2009) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Time Lines of Infection and Disease in Human Influenza: A Review of Volunteer Challenge Studies

(2008) Fabrice Carrat et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Agent-based modeling of host–pathogen systems: The successes and challenges

(2008) Amy L. Bauer et al.   INFORMATION SCIENCES