Selective inhibition of the NLRP3 inflammasome protects against acute ethanol-induced cardiotoxicity in an FBXL2-dependent manner

Mitophagy in cardiovascular diseases: molecular mechanisms, pathogenesis, and treatment

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Epigenetic modification in alcohol use disorder and alcoholic cardiomyopathy: From pathophysiology to therapeutic opportunities

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FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth

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Inflammasomes

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FUNDC1 interacts with FBXL2 to govern mitochondrial integrity and cardiac function through an IP3R3-dependent manner in obesity

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Curcumin suppresses doxorubicin-induced cardiomyocyte pyroptosis via a PI3K/Akt/mTOR-dependent manner

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Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

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CD74 knockout attenuates alcohol intake-induced cardiac dysfunction through AMPK-Skp2-mediated regulation of autophagy

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Mitochondrial calcium signaling as a therapeutic target for Alzheimer’s disease

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MicroRNA-21: Bridging Binge Drinking and Cardiovascular Health

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Effect of Alcohol Consumption on Cardiovascular Health

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The role of mitochondria in NLRP3 inflammasome activation

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Inflammasome-Independent Role of NLRP3 Mediates Mitochondrial Regulation in Renal Injury

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Spectroscopic, Polarographic, and Microcalorimetric Studies on Mitochondrial Dysfunction Induced by Ethanol

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NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

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Mitochondrial aldehyde dehydrogenase 2 deficiency aggravates energy metabolism disturbance and diastolic dysfunction in diabetic mice

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Mending a broken heart: the role of mitophagy in cardioprotection

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Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?

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Acetaldehyde dehydrogenase 2 (ALDH2) deficiency exacerbates pressure overload-induced cardiac dysfunction by inhibiting Beclin-1 dependent autophagy pathway

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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

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The protective effect of vitamin E against prenatal and early postnatal ethanol treatment-induced heart abnormality in rats: A 3-month follow-up study

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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

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Cardiovascular risks and benefits of moderate and heavy alcohol consumption

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Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain

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Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function

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Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy

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ULK1 Plays a Critical Role in AMPK-Mediated Myocardial Autophagy and Contractile Dysfunction following Acute Alcohol Challenge

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Molecular signaling toward mitophagy and its physiological significance

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Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis

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Deficiency in AMPK attenuates ethanol-induced cardiac contractile dysfunction through inhibition of autophagosome formation

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Angiotensin II Plays a Critical Role in Alcohol-Induced Cardiac Nitrative Damage, Cell Death, Remodeling, and Cardiomyopathy in a Protein Kinase C/Nicotinamide Adenine Dinucleotide Phosphate Oxidase–Dependent Manner

(2012) Yi Tan et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Regulation of inflammasome signaling

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FBXL2 is a ubiquitin E3 ligase subunit that triggers mitotic arrest

(2011) Bill B. Chen et al.   CELL CYCLE

Inflammation, Immunity, and Hypertension

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Sex difference in alcoholism: Who is at a greater risk for development of alcoholic complication?

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Alcohol and Acetaldehyde in Public Health: From Marvel to Menace

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Aldehyde Dehydrogenase 2 Ameliorates Acute Cardiac Toxicity of Ethanol

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Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice

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