From Discovery to Production: Biotechnology of Marine Fungi for the Production of New Antibiotics

Reprogramming the Biosynthesis of Cyclodepsipeptide Synthetases to Obtain New Enniatins and Beauvericins

(2016) Sophia Zobel et al.   CHEMBIOCHEM

Tet-on, or Tet-off, that is the question: Advanced conditional gene expression in Aspergillus

(2016) Franziska Wanka et al.   FUNGAL GENETICS AND BIOLOGY

Antioxidative phenolic compounds from a marine-derived fungus Aspergillus versicolor

(2016) Zehong Wu et al.   TETRAHEDRON

Antibacterial products of marine organisms

(2015) Tzi Bun Ng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Continuous downstream processing for high value biological products: A Review

(2015) Andrew L. Zydney   BIOTECHNOLOGY AND BIOENGINEERING

Identification of the Scopularide Biosynthetic Gene Cluster in Scopulariopsis brevicaulis

(2015) Mie Lukassen et al.   Marine Drugs

Production of Calcaride A by Calcarisporium sp. in Shaken Flasks and Stirred Bioreactors

(2015) Anu Tamminen et al.   Marine Drugs

Lindgomycin, an Unusual Antibiotic Polyketide from a Marine Fungus of the Lindgomycetaceae

(2015) Bin Wu et al.   Marine Drugs

Marine natural products

(2015) John W. Blunt et al.   NATURAL PRODUCT REPORTS

Heterologous production of fungal secondary metabolites in Aspergilli

(2015) Diana Chinyere Anyaogu et al.   Frontiers in Microbiology

Proteomic Analysis of Anti-Cancerous Scopularide Production by a Marine Microascus brevicaulis Strain and Its UV Mutant

(2015) Annemarie Kramer et al.   PLoS One

The Evolving Role of Chemical Synthesis in Antibacterial Drug Discovery

(2014) Peter M. Wright et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fermentation in 24-well plates is an efficient screening platform for filamentous fungi

(2014) T. Linde et al.   LETTERS IN APPLIED MICROBIOLOGY

Eliciting antibiotics active against the ESKAPE pathogens in a collection of actinomycetes isolated from mountain soils

(2014) H. Zhu et al.   MICROBIOLOGY-SGM

Design of Experiments (DoE) and Process Optimization. A Review of Recent Publications

(2014) Steven A. Weissman et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Development and Validation of a Fast and Optimized Screening Method for Enhanced Production of Secondary Metabolites Using the Marine Scopulariopsis brevicaulis Strain LF580 Producing Anti-Cancer Active Scopularide A and B

(2014) Annemarie Kramer et al.   PLoS One

Putting Fungi to Work: Harvesting a Cornucopia of Drugs, Toxins, and Antibiotics

(2014) Ulrich Kück et al.   PLoS Pathogens

Fungal diversity from various marine habitats deduced through culture-independent studies

(2013) Cathrine Sumathi Manohar et al.   FEMS MICROBIOLOGY LETTERS

Importance of microbial natural products and the need to revitalize their discovery

(2013) Arnold L. Demain   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Calcarides A–E, Antibacterial Macrocyclic and Linear Polyesters from a Calcarisporium Strain

(2013) Johanna Silber et al.   Marine Drugs

(±)-Pestalachloride D, an Antibacterial Racemate of Chlorinated Benzophenone Derivative from a Soft Coral-Derived Fungus Pestalotiopsis sp.

(2013) Mei-Yan Wei et al.   Marine Drugs

Recent Advances in the Discovery and Development of Marine Microbial Natural Products

(2013) Zhi-Qiang Xiong et al.   Marine Drugs

Continuous downstream processing of biopharmaceuticals

(2013) Alois Jungbauer   TRENDS IN BIOTECHNOLOGY

Upgrading Fungal Gene Expression on Demand: Improved Systems for Doxycycline-Dependent Silencing in Aspergillus fumigatus

(2012) Christoph Helmschrott et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Operating conditions optimization for (+)-terrein production in a stirred bioreactor by Aspergillus terreus strain PF-26 from marine sponge Phakellia fusca

(2012) Bailiang Xu et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Recent advances in the biosynthesis of penicillins, cephalosporins and clavams and its regulation

(2012) Gulay Ozcengiz et al.   BIOTECHNOLOGY ADVANCES

Aspergilli: Systems biology and industrial applications

(2012) Christoph Knuf et al.   Biotechnology Journal

Chemical Ecology of Endophytic Fungi: Origins of Secondary Metabolites

(2012) Souvik Kusari et al.   CHEMISTRY & BIOLOGY

Characterization and control of fungal morphology for improved production performance in biotechnology

(2012) Rainer Krull et al.   JOURNAL OF BIOTECHNOLOGY

Quinazolin-4-one Coupled with Pyrrolidin-2-iminium Alkaloids from Marine-Derived Fungus Penicillium aurantiogriseum

(2012) Fuhang Song et al.   Marine Drugs

Medium optimization for the high yield production of single (+)-terrein by Aspergillus terreus strain PF26 derived from marine sponge Phakellia fusca

(2012) Ying Yin et al.   PROCESS BIOCHEMISTRY

Science-based bioprocess design for filamentous fungi

(2012) Andreas E. Posch et al.   TRENDS IN BIOTECHNOLOGY

Secondary metabolites of fungi from marine habitats

(2011) Mostafa E. Rateb et al.   NATURAL PRODUCT REPORTS

Proteomics of eukaryotic microorganisms: The medically and biotechnologically important fungal genus Aspergillus

(2011) Olaf Kniemeyer   PROTEOMICS

Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteria

(2010) Patamaporn Pruksakorn et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Aspergillus as a multi-purpose cell factory: current status and perspectives

(2010) Vera Meyer et al.   BIOTECHNOLOGY LETTERS

Scale-down simulators for metabolic analysis of large-scale bioprocesses

(2010) Peter Neubauer et al.   CURRENT OPINION IN BIOTECHNOLOGY

Marine natural products as sources of novel scaffolds: achievement and concern

(2010) De-Xin Kong et al.   DRUG DISCOVERY TODAY

Fungal secondary metabolites – Strategies to activate silent gene clusters

(2010) Axel A. Brakhage et al.   FUNGAL GENETICS AND BIOLOGY

Marine Drugs from Sponge-Microbe Association—A Review

(2010) Tresa Remya A. Thomas et al.   Marine Drugs

Bioprocessing Data for the Production of Marine Enzymes

(2010) Sreyashi Sarkar et al.   Marine Drugs

Origins and Evolution of Antibiotic Resistance

(2010) J. Davies et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Methods for isolation of marine-derived endophytic fungi and their bioactive secondary products

(2010) Julia Kjer et al.   Nature Protocols

The antibiotics market

(2010) Bashar Hamad   NATURE REVIEWS DRUG DISCOVERY

Culturing marine bacteria - an essential prerequisite for biodiscovery

(2010) Ian Joint et al.   Microbial Biotechnology

Ascochytatin, a Novel Bioactive Spirodioxynaphthalene Metabolite Produced by the Marine-derived Fungus, Ascochyta sp. NGB4

(2009) Kaneo Kanoh et al.   JOURNAL OF ANTIBIOTICS

Validation of a high-throughput fermentation system based on online monitoring of biomass and fluorescence in continuously shaken microtiter plates

(2009) Frank Kensy et al.   Microbial Cell Factories

Triggering cryptic natural product biosynthesis in microorganisms

(2009) Kirstin Scherlach et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Antibiotic and antifouling compound production by the marine-derived fungus Cladosporium sp. F14

(2009) Hairong Xiong et al.   Journal of Hydro-environment Research

Synthesis of New N-Analogous Corollosporine Derivatives with Antibacterial Activity by Laccase-Catalyzed Amination

(2008) Annett Mikolasch et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Enhancement of antibiotic and secondary metabolite detection from filamentous fungi by growth on nutritional arrays

(2008) G.F. Bills et al.   JOURNAL OF APPLIED MICROBIOLOGY

In Vivo and In Vitro Production Options for Fungal Secondary Metabolites

(2008) Patrick Schneider et al.   MOLECULAR PHARMACEUTICS

Antifouling and antibacterial compounds from a marine fungus Cladosporium sp. F14

(2008) Shu-Hua Qi et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY