Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 21, Issue 1, Pages 114-121Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2010.02.001
Keywords
-
Funding
- UNICAT Centre of Excellence
- NEMO Network BioProScale
Ask authors/readers for more resources
Analytical approaches for a comprehensive understanding of the metabolic networks in microbial cultures are mostly based on small-scale cultures which are in a steady state or undergo dynamic changes For drawing conclusions to industrial-scale bioprocesses, however, it is important to understand that cells in large-scale bioreactors are exposed steadily to fast changes, because of an inhomogeneous environment Analytical approaches that aim for large-scale bioprocess understanding need to apply specific laboratory simulators. Recent developments in cell cultivation techniques and computational tools provide improved possibilities to evaluate how a process will behave in the final scale These simulators will pave the way for screening robust strains and process conditions
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available