Systematic review of the role of angiopoietin-1 and angiopoietin-2 in Plasmodium species infections: biomarkers or therapeutic targets?

C-reactive protein point-of-care testing in acutely ill children: a mixed methods study in primary care: Table 1

(2016) Ann Van den Bruel et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Alterations of blood coagulation in controlled human malaria infection

(2016) Julia Riedl et al.   MALARIA JOURNAL

Endothelial activation, haemostasis and thrombosis biomarkers in Ugandan children with severe malaria participating in a clinical trial

(2016) Susan M. Graham et al.   MALARIA JOURNAL

Acute Systemic Infection with Dengue Virus Leads to Vascular Leakage and Death through Tumor Necrosis Factor-α and Tie2/Angiopoietin Signaling in Mice Lacking Type I and II Interferon Receptors

(2016) Supranee Phanthanawiboon et al.   PLoS One

Microvascular obstruction and endothelial activation are independently associated with the clinical manifestations of severe falciparum malaria in adults: an observational study

(2015) Josh Hanson et al.   BMC Medicine

Inhaled nitric oxide as adjunctive therapy for severe malaria: a randomized controlled trial

(2015) Michael T. Hawkes et al.   MALARIA JOURNAL

The epidemiology of subclinical malaria infections in South-East Asia: findings from cross-sectional surveys in Thailand–Myanmar border areas, Cambodia, and Vietnam

(2015) Mallika Imwong et al.   MALARIA JOURNAL

Evaluation of point-of-care testing in critically unwell patients: comparison with clinical laboratory analysers and applicability to patients with Ebolavirus infection

(2015) Jen Kok et al.   PATHOLOGY

Impaired Systemic Tetrahydrobiopterin Bioavailability and Increased Oxidized Biopterins in Pediatric Falciparum Malaria: Association with Disease Severity

(2015) Matthew P. Rubach et al.   PLoS Pathogens

The Importance of Pathogen Load

(2015) Aubrey J. Cunnington   PLoS Pathogens

Parasite Biomass-Related Inflammation, Endothelial Activation, Microvascular Dysfunction and Disease Severity in Vivax Malaria

(2015) Bridget E. Barber et al.   PLoS Pathogens

Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial

(2015) Juliet Mwanga-Amumpaire et al.   Open Forum Infectious Diseases

Correction: Angiopoietin-2 and Angiopoietin-2/Angiopoietin-1 Ratio as Indicators of Potential Severity of Plasmodium vivax Malaria in Patients with Thrombocytopenia

(2015)   PLoS One

Plasmodium falciparumantigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria

(2014) Abdirahman I Abdi et al.   BMC INFECTIOUS DISEASES

Dimethylarginines: Endogenous Inhibitors of Nitric Oxide Synthesis in Children With Falciparum Malaria

(2014) Joe Brice Weinberg et al.   JOURNAL OF INFECTIOUS DISEASES

PPARγ Agonists Improve Survival and Neurocognitive Outcomes in Experimental Cerebral Malaria and Induce Neuroprotective Pathways in Human Malaria

(2014) Lena Serghides et al.   PLoS Pathogens

The mechanistic, diagnostic and prognostic utility of biomarkers in severe malaria

(2013) Laurens Manning et al.   Biomarkers in Medicine

Functional Roles for C5a and C5aR but Not C5L2 in the Pathogenesis of Human and Experimental Cerebral Malaria

(2013) Hani Kim et al.   INFECTION AND IMMUNITY

Persistent Endothelial Activation and Inflammation After Plasmodium falciparum Infection in Malawian Children

(2013) Christopher A. Moxon et al.   JOURNAL OF INFECTIOUS DISEASES

Rosiglitazone-induced CD36 up-regulation resolves inflammation by PPAR  and 5-LO-dependent pathways

(2013) I. Ballesteros et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Clinical relevance of different biomarkers in imported plasmodium falciparum malaria in adults: a case control study

(2013) Sabine Stauga et al.   MALARIA JOURNAL

A clinicopathological correlation of the expression of the angiopoietin-Tie-2 receptor pathway in the brain of adults with Plasmodium falciparum malaria

(2013) Panote Prapansilp et al.   MALARIA JOURNAL

Platelet Activation Determines Angiopoietin-1 and VEGF Levels in Malaria: Implications for Their Use as Biomarkers

(2013) Judith Brouwers et al.   PLoS One

Emerging therapeutic strategies to prevent infection-related microvascular endothelial activation and dysfunction

(2013) Ilyse Darwish et al.   Virulence

Biomarkers of endothelial activation/dysfunction in infectious diseases

(2013) Andrea V Page et al.   Virulence

Angiopoietin-2 levels are associated with retinopathy and predict mortality in Malawian children with cerebral malaria

(2012) Andrea L. Conroy et al.   CRITICAL CARE MEDICINE

Host immune response in returning travellers infected with malaria

(2012) Gregory MacMullin et al.   MALARIA JOURNAL

Endothelial activation and dysregulation in malaria: a potential target for novel therapeutics

(2011) Hani Kim et al.   CURRENT OPINION IN HEMATOLOGY

Plasma levels of angiopoietin-1 and -2 predict cerebral malaria outcome in Central India

(2011) Vidhan Jain et al.   MALARIA JOURNAL

Combinations of Host Biomarkers Predict Mortality among Ugandan Children with Severe Malaria: A Retrospective Case-Control Study

(2011) Laura K. Erdman et al.   PLoS One

Inhaled Nitric Oxide Reduces Endothelial Activation and Parasite Accumulation in the Brain, and Enhances Survival in Experimental Cerebral Malaria

(2011) Lena Serghides et al.   PLoS One

Adjunctive therapy for cerebral malaria and other severe forms ofPlasmodium falciparummalaria

(2010) Chandy C John et al.   Expert Review of Anti-Infective Therapy

Greater Endothelial Activation, Weibel‐Palade Body Release and Host Inflammatory Response toPlasmodium vivax,Compared withPlasmodium falciparum: A Prospective Study in Papua, Indonesia

(2010) Tsin W. Yeo et al.   JOURNAL OF INFECTIOUS DISEASES

On the Cytoadhesion ofPlasmodium vivax–Infected Erythrocytes

(2010) Bruna O. Carvalho et al.   JOURNAL OF INFECTIOUS DISEASES

Endothelium-Based Biomarkers Are Associated with Cerebral Malaria in Malawian Children: A Retrospective Case-Control Study

(2010) Andrea L. Conroy et al.   PLoS One

Increased Asymmetric Dimethylarginine in Severe Falciparum Malaria: Association with Impaired Nitric Oxide Bioavailability and Fatal Outcome

(2010) Tsin W. Yeo et al.   PLoS Pathogens

Rosiglitazone Modulates the Innate Immune Response toPlasmodium falciparumInfection and Improves Outcome in Experimental Cerebral Malaria

(2009) Lena Serghides et al.   JOURNAL OF INFECTIOUS DISEASES

Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria

(2009) Andrea L Conroy et al.   MALARIA JOURNAL

Angiopoietin 2 Is a Partial Agonist/Antagonist of Tie2 Signaling in the Endothelium

(2009) H. T. Yuan et al.   MOLECULAR AND CELLULAR BIOLOGY

Serum Angiopoietin-1 and -2 Levels Discriminate Cerebral Malaria from Uncomplicated Malaria and Predict Clinical Outcome in African Children

(2009) Fiona E. Lovegrove et al.   PLoS One

The murine cerebral malaria phenomenon

(2009) Nicholas J. White et al.   TRENDS IN PARASITOLOGY

The angiopoietin-Tie2 system as a therapeutic target in sepsis and acute lung injury

(2008) Melanie van der Heijden et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria

(2008) T. W. Yeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA