Plasmodium falciparumantigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria

Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children

(2013) C. A. Moxon et al.   BLOOD

Severe malaria is associated with parasite binding to endothelial protein C receptor

(2013) Louise Turner et al.   NATURE

DC8 and DC13 var Genes Associated with Severe Malaria Bind Avidly to Diverse Endothelial Cells

(2013) Marion Avril et al.   PLoS Pathogens

Angiopoietin-2 levels are associated with retinopathy and predict mortality in Malawian children with cerebral malaria

(2012) Andrea L. Conroy et al.   CRITICAL CARE MEDICINE

A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies

(2012) A. Bengtsson et al.   JOURNAL OF IMMUNOLOGY

Plasma Concentrations of Parasite Histidine-Rich Protein 2 Distinguish Between Retinopathy-Positive and Retinopathy-Negative Cerebral Malaria in Malawian Children

(2012) K. B. Seydel et al.   JOURNAL OF INFECTIOUS DISEASES

Relative Contributions of Macrovascular and Microvascular Dysfunction to Disease Severity in Falciparum Malaria

(2012) J. Hanson et al.   JOURNAL OF INFECTIOUS DISEASES

Abnormal PfEMP1/knob display on Plasmodium falciparum-infected erythrocytes containing hemoglobin variants: fresh insights into malaria pathogenesis and protection

(2012) Rick M. Fairhurst et al.   MICROBES AND INFECTION

A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

(2012) A. Claessens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells

(2012) M. Avril et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children

(2012) T. Lavstsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prognostic Indicators of Life-Threatening Malaria Are Associated with Distinct Parasite Variant Antigen Profiles

(2012) G. M. Warimwe et al.   Science Translational Medicine

Evolution of the Multi-Domain Structures of Virulence Genes in the Human Malaria Parasite, Plasmodium falciparum

(2012) Caroline O. Buckee et al.   PLoS Computational Biology

Diagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement

(2012) Ilse C. E. Hendriksen et al.   PLOS MEDICINE

Redefining cerebral malaria by including malaria retinopathy

(2011) Nicholas AV Beare et al.   Future Microbiology

Sequestration and Microvascular Congestion Are Associated With Coma in Human Cerebral Malaria

(2011) M. J. Ponsford et al.   JOURNAL OF INFECTIOUS DISEASES

Specific Receptor Usage in Plasmodium falciparum Cytoadherence Is Associated with Disease Outcome

(2011) Lucy B. Ochola et al.   PLoS One

A Role for Fetal Hemoglobin and Maternal Immune IgG in Infant Resistance to Plasmodium falciparum Malaria

(2011) Chanaki Amaratunga et al.   PLoS One

Investigating the Host Binding Signature on the Plasmodium falciparum PfEMP1 Protein Family

(2011) Joel H. Janes et al.   PLoS Pathogens

Identification of Malaria Retinopathy Improves the Specificity of the Clinical Diagnosis of Cerebral Malaria: Findings from a Prospective Cohort Study

(2010) Gretchen L. Birbeck et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Metabolic Acidosis Induced by Plasmodium Falciparum Intraerythrocytic Stages Alters Blood—Brain Barrier Integrity

(2010) Sergine Zougbédé et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Plasmodium falciparum-infected erythrocytes induce NF- B regulated inflammatory pathways in human cerebral endothelium

(2009) A. K. Tripathi et al.   BLOOD

Serum Angiopoietin-1 and -2 Levels Discriminate Cerebral Malaria from Uncomplicated Malaria and Predict Clinical Outcome in African Children

(2009) Fiona E. Lovegrove et al.   PLoS One

Plasmodium falciparum var gene expression is modified by host immunity

(2009) G. M. Warimwe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perfusion Abnormalities in Children with Cerebral Malaria and Malarial Retinopathy

(2008) Nicholas A. V. Beare et al.   JOURNAL OF INFECTIOUS DISEASES

Plasmodium falciparumantigenic variation. Mapping mosaicvargene sequences onto a network of shared, highly polymorphic sequence blocks

(2008) Peter C. Bull et al.   MOLECULAR MICROBIOLOGY

Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria

(2008) T. W. Yeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formation and function of Weibel-Palade bodies

(2007) D. J. Metcalf et al.   JOURNAL OF CELL SCIENCE

Direct In Vivo Assessment of Microcirculatory Dysfunction in Severe Falciparum Malaria

(2007) A. M. Dondorp et al.   JOURNAL OF INFECTIOUS DISEASES