Endotypes in bronchiectasis: moving towards precision medicine. A narrative review

Characterisation of Eosinophilic Bronchiectasis: A European Multicohort Study

(2022) Amelia Shoemark et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Microbiomics Focused Data Integration: A Fresh Solve for the Rubik’s Cube of Endophenotyping?

(2022) Jayanth Kumar Narayana et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Endotyping COPD, Bronchiectasis and the ‘COPD-bronchiectasis Association’

(2022) Jeffrey T.-J. Huang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Stenotrophomonas maltophilia in patients with bronchiectasis: An analysis of the US bronchiectasis and NTM Research Registry

(2022) Mark L. Metersky et al.   RESPIRATORY MEDICINE

Bronchiectasis enters the inflammation era

(2022) Holly R. Keir et al.   RESPIROLOGY

Genome sequencing reveals underdiagnosis of primary ciliary dyskinesia in bronchiectasis

(2022) Amelia Shoemark et al.   EUROPEAN RESPIRATORY JOURNAL

Shortened Telomere Length in Sputum Cells of Bronchiectasis Patients is Associated with Dysfunctional Inflammatory Pathways

(2022) Hui Fang Lim et al.   LUNG

Bronchiectasis — A Clinical Review

(2022) Anne E. O’Donnell   NEW ENGLAND JOURNAL OF MEDICINE

Bronchiectasis: A pulmonary disease with systemic consequences

(2022) Miguel Angel Martinez‐Garcia et al.   RESPIROLOGY

Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study

(2021) Holly R Keir et al.   Lancet Respiratory Medicine

Association of low fat mass with nontuberculous mycobacterial infection in patients with bronchiectasis

(2021) Sung Yoon Lim et al.   MEDICINE

Integrative microbiomics in bronchiectasis exacerbations

(2021) Micheál Mac Aogáin et al.   NATURE MEDICINE

Protease–Antiprotease Imbalance in Bronchiectasis

(2021) Martina Oriano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prevalence and Clinical Characteristics of Nontuberculous Mycobacteria in Patients with Bronchiectasis: A Systematic Review and Meta-Analysis

(2021) Ya-nan Zhu et al.   RESPIRATION

Bronchiectasis and Nontuberculous Mycobacteria: It Is Not Over till It Is Over

(2021) Hyung-Jun Kim et al.   RESPIRATION

Pathophysiology of Bronchiectasis

(2021) Holly R. Keir et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Clinical and Radiological Phenotypes and Endotypes

(2021) Ricardo J. José et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Prevalence and clinical implications of bronchiectasis in patients with overlapping asthma and chronic rhinosinusitis: a single-center prospective study

(2021) Haiyan Sheng et al.   BMC Pulmonary Medicine

Phenotypic Clustering in Non-Cystic Fibrosis Bronchiectasis Patients: The Role of Eosinophils in Disease Severity

(2021) Xuejie Wang et al.   International Journal of Environmental Research and Public Health

Rheumatoid arthritis-interstitial lung disease: manifestations and current concepts in pathogenesis and management

(2021) Suha Kadura et al.   European Respiratory Review

T2-High Endotype and Response to Biological Treatments in Patients with Bronchiectasis

(2021) Martina Oriano et al.   Biomedicines

Differences in Nutritional Status and Inflammatory Biomarkers between Female and Male Patients with Bronchiectasis: A Large-Cohort Study

(2021) Xuejie Wang et al.   Biomedicines

A Closer Look at the Role of Anti-CCP Antibodies in the Pathogenesis of Rheumatoid Arthritis-Associated Interstitial Lung Disease and Bronchiectasis

(2021) Tanjila Khan et al.   Rheumatology and Therapy

Prevalence and risk factors of bronchiectasis in rheumatoid arthritis: A systematic review and meta-analysis

(2021) Lily W. Martin et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Pulmonary Disease Burden in Primary Immune Deficiency Disorders: Data from USIDNET Registry

(2020) Meera Patrawala et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Serum Desmosine is Associated with Long-term All-cause and Cardiovascular Mortality in Bronchiectasis

(2020) Jeffrey T.-J. Huang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

C-Reactive Protein Concentration in Steady-State Bronchiectasis: Prognostic Value of Future Severe Exacerbations. Data From the Spanish Registry of Bronchiectasis (RIBRON)

(2020) Tomás Posadas et al.   ARCHIVOS DE BRONCONEUMOLOGIA

Increased Chitotriosidase Is Associated With Aspergillus and Frequent Exacerbations in South-East Asian Patients With Bronchiectasis

(2020) Tuang Yeow Poh et al.   CHEST

The Link between Asthma and Bronchiectasis: State of the Art

(2020) Claudia Crimi et al.   RESPIRATION

Utility of routine screening for alpha-1 antitrypsin deficiency in patients with bronchiectasis

(2020) Luis Carreto et al.   THORAX

Alpha-1-Antitrypsin Deficiency and Bronchiectasis: A Concomitance or a Real Association?

(2020) Alessandro Sanduzzi et al.   International Journal of Environmental Research and Public Health

Sputum neutrophil elastase in bronchiectasis: a Southern European cohort study

(2020) Andrea Gramegna et al.   EUROPEAN RESPIRATORY JOURNAL

Sputum Neutrophil Elastase associates with microbiota and P. aeruginosa in bronchiectasis

(2020) Martina Oriano et al.   EUROPEAN RESPIRATORY JOURNAL

The fungal airway microbiome in cystic fibrosis and non-cystic fibrosis bronchiectasis

(2020) Leah Cuthbertson et al.   Journal of Cystic Fibrosis

Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis

(2020) James D. Chalmers et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of inhaled corticosteroids in reducing exacerbations in bronchiectasis patients with blood eosinophilia pooled post-hoc analysis of 2 randomized clinical trials

(2020) Miguel Angel Martinez-Garcia et al.   RESPIRATORY MEDICINE

Impact of Bronchiectasis on incident NTM pulmonary disease: A 10-Year national cohort study

(2020) Bumhee Yang et al.   CHEST

The detrimental qualitative and quantitative alterations of circulating endothelial progenitor cells in patients with bronchiectasis

(2020) Yangli Liu et al.   RESPIRATORY MEDICINE

A Cluster Analysis of Bronchiectasis Patients Based on the Airway Immune Profile

(2020) Lídia Perea et al.   CHEST

Inhaled liposomal ciprofloxacin in patients with non-cystic fibrosis bronchiectasis and chronic lung infection with Pseudomonas aeruginosa (ORBIT-3 and ORBIT-4): two phase 3, randomised controlled trials

(2019) Charles S Haworth et al.   Lancet Respiratory Medicine

Severe asthma and bronchiectasis

(2019) Marta García-Clemente et al.   JOURNAL OF ASTHMA

Airway Bacterial Load and Inhaled Antibiotic Response in Bronchiectasis

(2019) Oriol Sibila et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Factors Beyond Lack of Antibody Govern Pulmonary Complications in Primary Antibody Deficiency

(2019) Tamar Weinberger et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Pulmonary and Bronchiolar Involvement in Sjogren's Syndrome

(2019) Augustine Chung et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Pregnancy Zone Protein is Associated with Airway Infection, Neutrophil Extracellular Trap Formation and Disease Severity in Bronchiectasis

(2019) Simon Finch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A point-of-care neutrophil elastase activity assay identifies bronchiectasis severity, airway infection and risk of exacerbation

(2019) Amelia Shoemark et al.   EUROPEAN RESPIRATORY JOURNAL

Antimicrobial peptides, disease severity and exacerbations in bronchiectasis

(2019) Oriol Sibila et al.   THORAX

A longitudinal characterization of the Non-Cystic Fibrosis Bronchiectasis airway microbiome

(2019) T. E. Woo et al.   Scientific Reports

Pulmonary Manifestations of Inflammatory Bowel Disease

(2019) Annie Massart et al.   AMERICAN JOURNAL OF MEDICINE

The microbiome in bronchiectasis

(2019) Hollian Richardson et al.   European Respiratory Review

Airway Mucus Hyperconcentration in Non-Cystic Fibrosis Bronchiectasis

(2019) Kathryn A Ramsey et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Anti-IL5 and anti-IL5Rα therapy for clinically significant bronchiectasis with eosinophilic endotype: a case series

(2019) Jessica Rademacher et al.   EUROPEAN RESPIRATORY JOURNAL

Long-term macrolide antibiotics for the treatment of bronchiectasis in adults: an individual participant data meta-analysis

(2019) James D Chalmers et al.   Lancet Respiratory Medicine

Primary ciliary dyskinesia in the genomics age

(2019) Jane S Lucas et al.   Lancet Respiratory Medicine

IMMUNOLOGICAL COROLLARY OF THE PULMONARY MYCOBIOME IN BRONCHIECTASIS: THE CAMEB STUDY

(2018) Micheál Mac Aogáin et al.   EUROPEAN RESPIRATORY JOURNAL

The independent contribution of Pseudomonas aeruginosa infection to long-term clinical outcomes in bronchiectasis

(2018) David Araújo et al.   EUROPEAN RESPIRATORY JOURNAL

Secreted phosphatase and deoxyribonuclease are required by Pseudomonas aeruginosa to defend against neutrophil extracellular traps.

(2018) Mike Wilton et al.   INFECTION AND IMMUNITY

Fungi in Bronchiectasis: A Concise Review

(2018) Luis Máiz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk

(2018) M.J. McDonnell et al.   RESPIRATORY MEDICINE

Viruses in bronchiectasis: a pilot study to explore the presence of community acquired respiratory viruses in stable patients and during acute exacerbations

(2018) Alicia B. Mitchell et al.   BMC Pulmonary Medicine

Geographic variation in the aetiology, epidemiology and microbiology of bronchiectasis

(2018) Ravishankar Chandrasekaran et al.   BMC Pulmonary Medicine

Bronchiectasis: new therapies and new perspectives

(2018) James D Chalmers et al.   Lancet Respiratory Medicine

Distinct 'Immuno-Allertypes' of Disease and High Frequencies of Sensitisation in Non-Cystic-Fibrosis Bronchiectasis

(2018) Micheál Mac Aogáin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Treatable traits in bronchiectasis

(2018) Rita Boaventura et al.   EUROPEAN RESPIRATORY JOURNAL

Proteobacteria community compositions correlate with bronchiectasis severity

(2018) W-J. Guan et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity

(2018) Patrick A Flume et al.   LANCET

A New Bronchiectasis Endophenotype: Immuno-allertypes.

(2018) Pamela J McShane   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pseudomonas aeruginosaadaptation and diversification in the non-cystic fibrosis bronchiectasis lung

(2017) Yasmin Hilliam et al.   EUROPEAN RESPIRATORY JOURNAL

Precision medicine in airway diseases: moving to clinical practice

(2017) Alvar Agustí et al.   EUROPEAN RESPIRATORY JOURNAL

European Respiratory Society statement: diagnosis and treatment of pulmonary disease in α1-antitrypsin deficiency

(2017) Marc Miravitlles et al.   EUROPEAN RESPIRATORY JOURNAL

The microbiome in respiratory medicine: current challenges and future perspectives

(2017) Rosa Faner et al.   EUROPEAN RESPIRATORY JOURNAL

European Respiratory Society guidelines for the management of adult bronchiectasis

(2017) Eva Polverino et al.   EUROPEAN RESPIRATORY JOURNAL

The heterogeneity of systemic inflammation in bronchiectasis

(2017) Aarash D. Saleh et al.   RESPIRATORY MEDICINE

Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients

(2017) Michael J. Cox et al.   PLoS One

Lung-gut cross-talk: evidence, mechanisms and implications for the mucosal inflammatory diseases

(2016) M. K. Tulic et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Hyper-IgE Syndromes and the Lung

(2016) Alexandra F. Freeman et al.   CLINICS IN CHEST MEDICINE

European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia

(2016) Jane S. Lucas et al.   EUROPEAN RESPIRATORY JOURNAL

Treatable traits: toward precision medicine of chronic airway diseases

(2016) Alvar Agusti et al.   EUROPEAN RESPIRATORY JOURNAL

Respiratory Health and Related Quality of Life in Patients with Congenital Agammaglobulinemia in the Northern Region of the UK

(2016) Branwen A. Bryan et al.   JOURNAL OF CLINICAL IMMUNOLOGY

FUT2 genotype influences lung function, exacerbation frequency and airway microbiota in non-CF bronchiectasis

(2016) Steven L Taylor et al.   THORAX

Bronchiectasis and the risk of cardiovascular disease: a population-based study

(2016) Vidya Navaratnam et al.   THORAX

Inflammatory bowel disease and airway diseases

(2016) Maria Vutcovici et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Pulmonary manifestations of inflammatory bowel disease

(2015) Sebastian Majewski et al.   Archives of Medical Science

The Role of Viral Infection in Pulmonary Exacerbations of Bronchiectasis in Adults

(2015) Yong-hua Gao et al.   CHEST

COPD–bronchiectasis overlap syndrome

(2015) John R. Hurst et al.   EUROPEAN RESPIRATORY JOURNAL

Prevalence and Factors Associated with Isolation of Aspergillus and Candida from Sputum in Patients with Non-Cystic Fibrosis Bronchiectasis

(2015) Luis M�iz et al.   RESPIRATION

Sputum matrix metalloproteinase-8 and -9 and tissue inhibitor of metalloproteinase-1 in bronchiectasis: Clinical correlates and prognostic implications

(2015) Wei-jie Guan et al.   RESPIROLOGY

Secreted mucins and airway bacterial colonization in non-CF bronchiectasis

(2015) Oriol Sibila et al.   RESPIROLOGY

Pulmonary radiologic findings in common variable immunodeficiency: clinical and immunological correlations

(2014) Paul J. Maglione et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia

(2014) Julia Wallmeier et al.   NATURE GENETICS

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhaled mannitol for non-cystic fibrosis bronchiectasis: a randomised, controlled trial

(2014) Diana Bilton et al.   THORAX

MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia

(2014) Mieke Boon et al.   Nature Communications

Deletion of airway cilia results in noninflammatory bronchiectasis and hyperreactive airways

(2013) Sandra K. Gilley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Lung Microbiota and Bacterial Abundance in Patients with Bronchiectasis when Clinically Stable and during Exacerbation

(2013) Michael M. Tunney et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mannose-binding lectin deficiency and disease severity in non-cystic fibrosis bronchiectasis: a prospective study

(2013) James D Chalmers et al.   Lancet Respiratory Medicine

Mechanisms of immune dysfunction and bacterial persistence in non-cystic fibrosis bronchiectasis

(2012) James D. Chalmers et al.   MOLECULAR IMMUNOLOGY

Bronquiectasias, inflamación sistémica y factor de necrosis tumoral alfa: factores asociados

(2008) Miguel Ángel Martínez-García et al.   ARCHIVOS DE BRONCONEUMOLOGIA