Neutrophil extracellular traps, disease severity, and antibiotic response in bronchiectasis: an international, observational, multicohort study

Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis

(2020) James D. Chalmers et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhaled liposomal ciprofloxacin in patients with non-cystic fibrosis bronchiectasis and chronic lung infection with Pseudomonas aeruginosa (ORBIT-3 and ORBIT-4): two phase 3, randomised controlled trials

(2019) Charles S Haworth et al.   Lancet Respiratory Medicine

Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0)

(2019) Huaiyu Mi et al.   Nature Protocols

A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma

(2019) Michael Fricker et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pregnancy Zone Protein is Associated with Airway Infection, Neutrophil Extracellular Trap Formation and Disease Severity in Bronchiectasis

(2019) Simon Finch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A point-of-care neutrophil elastase activity assay identifies bronchiectasis severity, airway infection and risk of exacerbation

(2019) Amelia Shoemark et al.   EUROPEAN RESPIRATORY JOURNAL

Extracellular Chromatin Triggers Release of Soluble CEACAM8 Upon Activation of Neutrophils

(2019) Matthieu Ribon et al.   Frontiers in Immunology

Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry

(2019) Raja Dhar et al.   Lancet Global Health

Long-term macrolide antibiotics for the treatment of bronchiectasis in adults: an individual participant data meta-analysis

(2019) James D Chalmers et al.   Lancet Respiratory Medicine

The independent contribution of Pseudomonas aeruginosa infection to long-term clinical outcomes in bronchiectasis

(2018) David Araújo et al.   EUROPEAN RESPIRATORY JOURNAL

Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease

(2018) Alison J. Dicker et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Evaluation of the airway microbiome in non-tuberculous mycobacteria

(2018) Imran Sulaiman et al.   EUROPEAN RESPIRATORY JOURNAL

Pulmonary exacerbation in adults with bronchiectasis: a consensus definition for clinical research

(2017) Adam T. Hill et al.   EUROPEAN RESPIRATORY JOURNAL

European Respiratory Society guidelines for the management of adult bronchiectasis

(2017) Eva Polverino et al.   EUROPEAN RESPIRATORY JOURNAL

Azithromycin and Chloramphenicol Diminish Neutrophil Extracellular Traps (NETs) Release

(2017) Weronika Bystrzycka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial

(2017) Peter G Gibson et al.   LANCET

Multidimensional severity assessment in bronchiectasis: an analysis of seven European cohorts

(2016) M J McDonnell et al.   THORAX

A randomised, placebo-controlled study of the CXCR2 antagonist AZD5069 in bronchiectasis

(2015) Anthony De Soyza et al.   EUROPEAN RESPIRATORY JOURNAL

Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study

(2015) Jennifer K. Quint et al.   EUROPEAN RESPIRATORY JOURNAL

The Bronchiectasis Severity Index. An International Derivation and Validation Study

(2014) James D. Chalmers et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Papillon-Lefèvre syndrome patient reveals species-dependent requirements for neutrophil defenses

(2014) Ole E. Sørensen et al.   JOURNAL OF CLINICAL INVESTIGATION

A randomized double blind, placebo controlled phase 2 trial of BIIL 284 BS (an LTB4 receptor antagonist) for the treatment of lung disease in children and adults with cystic fibrosis

(2014) M.W. Konstan et al.   Journal of Cystic Fibrosis

Cystic Fibrosis Sputum DNA Has NETosis Characteristics and Neutrophil Extracellular Trap Release Is Regulated by Macrophage Migration-Inhibitory Factor

(2014) Markryan Dwyer et al.   Journal of Innate Immunity

Quality of Life Questionnaire-Bronchiectasis: final psychometric analyses and determination of minimal important difference scores

(2014) Alexandra L Quittner et al.   THORAX

A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis

(2014) Kathleen D. Metzler et al.   Cell Reports

The effect of long-term macrolide treatment on respiratory microbiota composition in non-cystic fibrosis bronchiectasis: an analysis from the randomised, double-blind, placebo-controlled BLESS trial

(2014) Geraint B Rogers et al.   Lancet Respiratory Medicine

Azithromycin for prevention of exacerbations in non-cystic fibrosis bronchiectasis (EMBRACE): a randomised, double-blind, placebo-controlled trial

(2012) Conroy Wong et al.   LANCET

Neutrophil Extracellular Trap (NET)-Mediated Killing of Pseudomonas aeruginosa: Evidence of Acquired Resistance within the CF Airway, Independent of CFTR

(2011) Robert L. Young et al.   PLoS One

Neutrophil Elastase Enhances Sputum Solubilization in Cystic Fibrosis Patients Receiving DNase Therapy

(2011) Venizelos Papayannopoulos et al.   PLoS One