Modes of Action of 1,8-Cineol in Infections and Inflammation

Fabrication of a Polysaccharide-Protein/Protein Complex Stabilized Oral Nanoemulsion to Facilitate the Therapeutic Effects of 1,8-Cineole on Atherosclerosis

(2023) Yi Chen et al.   ACS Nano

Antibacterial activity and synergic effects of the essential oils of Amomum verum Blackw and Zanthoxylum limonella (Dennst.) Alston

(2023) Sarunpron Khruengsai et al.   ARCHIVES OF MICROBIOLOGY

Study on the opening effect of eucalyptol on the blood–brain barrier and its brain pharmacokinetics

(2023) Ligema Dao et al.   BIOMEDICAL CHROMATOGRAPHY

Molecular Docking Identifies 1,8-Cineole (Eucalyptol) as A Novel PPARγ Agonist That Alleviates Colon Inflammation

(2023) Balaji Venkataraman et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Determination of orally administered 1,8-Cineol in nasal polyp tissues from chronic rhinosinusitis patients using gas chromatography: mass spectrometry

(2023) Claire MacKenzie et al.   Scientific Reports

Bacterial colonization differences between central compartment atopic disease and eosinophilic chronic rhinosinusitis

(2023) Darren Rom et al.   International Forum of Allergy & Rhinology

Anti-inflammatory mechanisms of eucalyptol rich Eucalyptus globulus essential oil alone and in combination with flurbiprofen

(2023) Bushra Arooj et al.   INFLAMMOPHARMACOLOGY

Antibacterial Properties of Eucalyptus globulus Essential Oil against MRSA: A Systematic Review

(2023) Shakthi Elangovan et al.   Antibiotics-Basel

Inhibitory Activity of Essential Oils of Mentha spicata and Eucalyptus globulus on Biofilms of Streptococcus mutans in an In Vitro Model

(2023) Guillermo Ernesto Landeo-Villanueva et al.   Antibiotics-Basel

Chemical Composition and Antimicrobial Potential of a Plant-Based Substance for the Treatment of Seborrheic Dermatitis

(2023) Viktor A. Filatov et al.   Pharmaceuticals

Early growth response-1: Key mediators of cell death and novel targets for cardiovascular disease therapy

(2023) Yixin Xie et al.   Frontiers in Cardiovascular Medicine

Essential Oil Composition Analysis, Antimicrobial Activities, and Biosystematic Studies on Six Species of Salvia

(2023) Azize Demirpolat   Life-Basel

Microbiome and Th cytokines association in chronic rhinosinusitis with or without nasal polyp

(2023) ZhongShou Zhu et al.   Laryngoscope Investigative Otolaryngology

1,8 Cineole and Ellagic acid inhibit hepatocarcinogenesis via upregulation of MiR-122 and suppression of TGF-β1, FSCN1, Vimentin, VEGF, and MMP-9

(2022) Heba M. I. Abdallah et al.   PLoS One

Lavandula viridis L´Hér. Essential Oil Inhibits the Inflammatory Response in Macrophages Through Blockade of NF-KB Signaling Cascade

(2022) Monica Zuzarte et al.   Frontiers in Pharmacology

Eucalyptol prevents bleomycin-induced pulmonary fibrosis and M2 macrophage polarization

(2022) Yan Rui et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

1,8-Cineole Ameliorates Advanced Glycation End Products-Induced Alzheimer’s Disease-like Pathology In Vitro and In Vivo

(2022) Fengmao An et al.   MOLECULES

The leaves of the seasoning plant Litsea cubeba inhibit the NLRP3 inflammasome and ameliorate dextran sulfate sodium-induced colitis in mice

(2022) Wei-Ting Wong et al.   Frontiers in Nutrition

RIFM fragrance ingredient safety assessment, γ-hexalactone, CAS Registry Number 695-06-7

(2022) A.M. Api et al.   FOOD AND CHEMICAL TOXICOLOGY

Cineole regulates Wnt/β-catenin pathway through Nrf2/keap1/ROS to inhibit bisphenol A-induced apoptosis, autophagy inhibition and immunosuppression of grass carp hepatocytes

(2022) Lu Chen et al.   FISH & SHELLFISH IMMUNOLOGY

Osmotic stress relief antibiotic tolerance of 1,8-cineole in biofilm persister cells of Escherichia coli O157:H7 and expression of toxin-antitoxin system genes

(2022) Keren Agyekumwaa Addo et al.   MICROBIAL PATHOGENESIS

Treatment with Glyphosate Induces Tolerance of Citrus Pathogens to Glyphosate and Fungicides but Not to 1,8-Cineole

(2022) Nor EL Houda Tahiri et al.   MOLECULES

In Vitro Assessment of Antimicrobial Activity of Phytobiotics Composition towards of Avian Pathogenic Escherichia coli (APEC) and Other E. coli Strains Isolated from Broiler Chickens

(2022) Karolina A. Chodkowska et al.   Antibiotics-Basel

Quantification of eucalyptol (1,8‐cineole) in rat serum by gas chromatography–mass/mass spectrometry and its application to a rat pharmacokinetic study

(2021) Chula Sa et al.   BIOMEDICAL CHROMATOGRAPHY

Cineole-containing nanoemulsion: Development, stability, and antibacterial activity

(2021) Tayonara S. Lima et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Clinicopathologic and molecular characterization of melanomas mutated for CTNNB1 and MAPK

(2021) Bénédicte Oulès et al.   VIRCHOWS ARCHIV

Effect of thermal liquefaction on quality, chemical composition and antibiofilm activity against multiresistant human pathogens of crystallized eucalyptus honey

(2021) Irina Villacrés-Granda et al.   FOOD CHEMISTRY

Antimicrobial activity and mode of action of 1,8-cineol against carbapenemase-producing Klebsiella pneumoniae

(2021) Chew-Li Moo et al.   Scientific Reports

Early Growth Response‐1, an Integrative Sensor in Cardiovascular and Inflammatory Disease

(2021) Levon M. Khachigian   Journal of the American Heart Association

1,8-Cineole Affects Agonists-Induced Platelet Activation, Thrombus Formation and Haemostasis

(2021) Kahdr A. Alatawi et al.   Cells

New Perspectives for Mucolytic, Anti-inflammatory and Adjunctive Therapy with 1,8-Cineole in COPD and Asthma: Review on the New Therapeutic Approach

(2020) Lisa Joy Juergens et al.   ADVANCES IN THERAPY

Bacterial Quorum Sensing During Infection

(2020) Sheyda Azimi et al.   Annual Review of Microbiology

Preparation of Terpenoid-Invasomes with Selective Activity against S. aureus and Characterization by Cryo Transmission Electron Microscopy

(2020) Bernhard P. Kaltschmidt et al.   Biomedicines

Eucalyptus oil reduces allergic reactions and suppresses mast cell degranulation by downregulating IgE-FcεRI signalling

(2020) Tomoya Nakamura et al.   Scientific Reports

Bacterial quorum sensing in complex and dynamically changing environments

(2019) Sampriti Mukherjee et al.   NATURE REVIEWS MICROBIOLOGY

Suppression of Propionibacterium acnes-Induced Skin Inflammation by Laurus nobilis Extract and Its Major Constituent Eucalyptol

(2019) Eun Hye Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Therapeutic Effect of 1,8-Cineol on Pathogenic Bacteria Species Present in Chronic Rhinosinusitis

(2019) Matthias Schürmann et al.   Frontiers in Microbiology

A Comprehensive Review on MAPK: A Promising Therapeutic Target in Cancer

(2019) Braicu et al.   Cancers

Eucalyptol alleviates inflammation and pain responses in a mouse model of gout arthritis

(2019) Chengyu Yin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Development of galangal essential oil-based microemulsion gel for transdermal delivery of flurbiprofen: simultaneous permeability evaluation of flurbiprofen and 1,8-cineole

(2019) Jie Dong et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Increased phosphorylation of eNOS in nasal polyps of chronic rhinosinusitis patients can be diminished by 1,8-cineol

(2018) Michael Koennecke et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

1,8-cineol inhibits the Wnt/β-catenin signaling pathway through GSK-3 dephosphorylation in nasal polyps of chronic rhinosinusitis patients

(2018) Karl-Ludwig Bruchhage et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Chronic rhinosinusitis: pathogenesis, therapy options, and more

(2018) Umut Can Kucuksezer et al.   EXPERT OPINION ON PHARMACOTHERAPY

Prevalence of chronic rhinosinusitis in the general population based on sinus radiology and symptomatology

(2018) Dirk Dietz de Loos et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Laurus nobilis leaf extract controls inflammation by suppressing NLRP3 inflammasome activation

(2018) Eun Hye Lee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Intranasal co-administration of 1,8-cineole with influenza vaccine provide cross-protection against influenza virus infection

(2017) Yun Li et al.   PHYTOMEDICINE

Suppression of inflammatory and infection responses in lung macrophages by eucalyptus oil and its constituent 1,8-cineole: Role of pattern recognition receptors TREM-1 and NLRP3, the MAP kinase regulator MKP-1, and NFκB

(2017) Niket Yadav et al.   PLoS One

1,8-cineole prevents UVB-induced skin carcinogenesis by targeting the aryl hydrocarbon receptor

(2017) Jangho Lee et al.   Oncotarget

Inhibitory Effect of 1,8-Cineol on β-Catenin Regulation, WNT11 Expression, and Cellular Progression in HNSCC

(2017) Anna Roettger et al.   Frontiers in Oncology

Effect of 1.8-Cineole in Dermatophagoides pteronyssinus-Stimulated Bronchial Epithelial Cells and Mouse Model of Asthma

(2016) Hyun-Seung Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

1,8-Cineole potentiates IRF3-mediated antiviral response in human stem cells and in an ex vivo model of rhinosinusitis

(2016) J. Muller et al.   CLINICAL SCIENCE

Medicinal Plants of the Australian Aboriginal Dharawal People Exhibiting Anti-Inflammatory Activity

(2016) Most A. Akhtar et al.   Evidence-based Complementary and Alternative Medicine

1, 8-Cineol Protect Against Influenza-Virus-Induced Pneumonia in Mice

(2016) Yun Li et al.   INFLAMMATION

Glycogen synthase kinase 3 in Wnt signaling pathway and cancer

(2015) Nydia Tejeda-Muñoz et al.   IUBMB LIFE

Eucalyptol suppresses matrix metalloproteinase-9 expression through an extracellular signal-regulated kinase-dependent nuclear factor-kappa B pathway to exert anti-inflammatory effects in an acute lung inflammation model

(2015) Ka Young Kim et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

1,8-Cineol Reduces Mucus-Production in a Novel Human Ex Vivo Model of Late Rhinosinusitis

(2015) Holger Sudhoff et al.   PLoS One

The eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage

(2014) Bastian Dörsam et al.   ARCHIVES OF TOXICOLOGY

1,8-Cineol inhibits nuclear translocation of NF-κB p65 and NF-κB-dependent transcriptional activity

(2013) Johannes F.-W. Greiner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The P110 subunit of PI3-K is a therapeutic target of acacetin in skin cancer

(2013) Sung Keun Jung et al.   CARCINOGENESIS

1,8-Cineole (Eucalyptol) Mitigates Inflammation in Amyloid Beta Toxicated PC12 Cells: Relevance to Alzheimer’s Disease

(2013) Andleeb Khan et al.   NEUROCHEMICAL RESEARCH

Inhibition of biofilm development of uropathogens by curcumin – An anti-quorum sensing agent from Curcuma longa

(2012) Issac Abraham Sybiya Vasantha Packiavathy et al.   FOOD CHEMISTRY

Inhaled 1,8-Cineole Reduces Inflammatory Parameters in Airways of Ovalbumin-Challenged Guinea Pigs

(2010) Vasco P.D. Bastos et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Quantification of 1,8-cineole and of its metabolites in humans using stable isotope dilution assays

(2010) Kathie Horst et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Real-time breath gas analysis for pharmacokinetics: monitoring exhaled breath by on-line proton-transfer-reaction mass spectrometry after ingestion of eucalyptol-containing capsules

(2010) J Beauchamp et al.   Journal of Breath Research

Variations in Essential Oil, Phenolic Compounds, and Antioxidant Activity of Tunisian Cultivated Salvia officinalis L.

(2009) Mouna Ben Farhat et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Myricetin Suppresses UVB-Induced Skin Cancer by Targeting Fyn

(2008) S. K. Jung et al.   CANCER RESEARCH

Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1–Cul3 interaction

(2008) Xiao-Jun Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY