Molecular Docking Identifies 1,8-Cineole (Eucalyptol) as A Novel PPARγ Agonist That Alleviates Colon Inflammation

Lavandula viridis L´Hér. Essential Oil Inhibits the Inflammatory Response in Macrophages Through Blockade of NF-KB Signaling Cascade

(2022) Monica Zuzarte et al.   Frontiers in Pharmacology

α-Bisabolol Mitigates Colon Inflammation by Stimulating Colon PPAR-γ Transcription Factor: In Vivo and In Vitro Study

(2022) Balaji Venkataraman et al.   PPAR Research

Heme Oxygenase-1: An Anti-Inflammatory Effector in Cardiovascular, Lung, and Related Metabolic Disorders

(2022) Stefan W. Ryter   Antioxidants

Cineole regulates Wnt/β-catenin pathway through Nrf2/keap1/ROS to inhibit bisphenol A-induced apoptosis, autophagy inhibition and immunosuppression of grass carp hepatocytes

(2022) Lu Chen et al.   FISH & SHELLFISH IMMUNOLOGY

Anti-Inflammatory Activities of Constituents from Cinnamomum insularimontanum Hayata Leaves and Their Mechanisms

(2022) Chieh-Yin Chen et al.   Plants-Basel

PPARgamma in Metabolism, Immunity, and Cancer: Unified and Diverse Mechanisms of Action

(2021) Miguel Hernandez-Quiles et al.   Frontiers in Endocrinology

Thymoquinone, a Dietary Bioactive Compound, Exerts Anti-Inflammatory Effects in Colitis by Stimulating Expression of the Colonic Epithelial PPAR-γ Transcription Factor

(2021) Balaji Venkataraman et al.   Nutrients

Role of Oxidative Stress and Nrf2/KEAP1 Signaling in Colorectal Cancer: Mechanisms and Therapeutic Perspectives with Phytochemicals

(2021) Da-Young Lee et al.   Antioxidants

Peroxisome Proliferator-Activated Receptors: Experimental Targeting for the Treatment of Inflammatory Bowel Diseases

(2020) Juan Decara et al.   Frontiers in Pharmacology

NRF2, a Transcription Factor for Stress Response and Beyond

(2020) Feng He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nerolidol Mitigates Colonic Inflammation: An Experimental Study Using both In Vivo and In Vitro Models

(2020) Vishnu Raj et al.   Nutrients

Biochemical Research of the Effects of Essential Oil Obtained from the Fruit of Myrtus communis L. on Cell Damage Associated with Lipopolysaccharide-Induced Endotoxemia in a Human Umbilical Cord Vein Endothelial Cells

(2020) Zerrin Kutlu et al.   BIOCHEMICAL GENETICS

1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-γ Dependent Regulation of NF-κB

(2019) Ke-Gang Linghu et al.   Frontiers in Pharmacology

The Essential Oils and Eucalyptol From Artemisia vulgaris L. Prevent Acetaminophen-Induced Liver Injury by Activating Nrf2–Keap1 and Enhancing APAP Clearance Through Non-Toxic Metabolic Pathway

(2019) Zhihui Jiang et al.   Frontiers in Pharmacology

Frondanol, a Nutraceutical Extract from Cucumaria frondosa, Attenuates Colonic Inflammation in a DSS-Induced Colitis Model in Mice

(2018) Sandeep Subramanya et al.   Marine Drugs

Intestinal in vitro cell culture models and their potential to study the effect of food components on intestinal inflammation

(2018) Maria del Carmen Ponce de León-Rodríguez et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Preparation and protective effects of 1,8-cineole-loaded self-microemulsifying drug delivery system on lipopolysaccharide-induced endothelial injury in mice

(2018) Feng Jiang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Suppression of inflammatory and infection responses in lung macrophages by eucalyptus oil and its constituent 1,8-cineole: Role of pattern recognition receptors TREM-1 and NLRP3, the MAP kinase regulator MKP-1, and NFκB

(2017) Niket Yadav et al.   PLoS One

Effect of 1.8-Cineole in Dermatophagoides pteronyssinus-Stimulated Bronchial Epithelial Cells and Mouse Model of Asthma

(2016) Hyun-Seung Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Mentha longifolia protects against acetic-acid induced colitis in rats

(2016) Hussam A.S. Murad et al.   JOURNAL OF ETHNOPHARMACOLOGY

Association of HMOX1 and NQO1 Polymorphisms with Metabolic Syndrome Components

(2015) Angélica Martínez-Hernández et al.   PLoS One

1,8-Cineol Attenuates LPS-Induced Acute Pulmonary Inflammation in Mice

(2013) Chunzhen Zhao et al.   INFLAMMATION

Peroxisome proliferator-activated receptor gamma overexpression suppresses proliferation of human colon cancer cells

(2012) Tamotsu Tsukahara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PPARγin Inflammatory Bowel Disease

(2012) Vito Annese et al.   PPAR Research

Persistent Cyclooxygenase-2 Inhibition Downregulates NF-κB, Resulting in Chronic Intestinal Inflammation in the Min/+ Mouse Model of Colon Tumorigenesis

(2010) Adelaide M. Carothers et al.   CANCER RESEARCH

The essential role of Oct-2 in LPS-induced expression of iNOS in RAW 264.7 macrophages and its regulation by trichostatin A

(2009) Shao-Chun Lu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Regulation of Th17 Differentiation by Epidermal Fatty Acid-Binding Protein

(2009) B. Li et al.   JOURNAL OF IMMUNOLOGY

Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice

(2008) Reiko Ito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NF-κB in inflammatory bowel disease

(2008) I. Atreya et al.   JOURNAL OF INTERNAL MEDICINE